TY - JOUR
T1 - 2D Images Recorded With a Single-Sided Magnetic Particle Imaging Scanner
AU - Gräfe, Ksenija
AU - von Gladiß, Anselm
AU - Bringout, Gael
AU - Ahlborg, Mandy
AU - Buzug, Thorsten M.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Magnetic Particle Imaging is a new medical imaging modality, which detects superparamagnetic iron oxide nanoparticles. The particles are excited by magnetic fields. Most scanners have a tube-like measurement field and therefore, both the field of view and the object size are limited. A single-sided scanner has the advantage that the object is not limited in size, only the penetration depth is limited. A single-sided scanner prototype for 1D imaging has been presented in 2009. Simulations have been published for a 2D single-sided scanner and first 1D measurements have been carried out. In this paper, the first 2D single-sided scanner prototype is presented and the first calibration-based reconstruction results of measured 2D phantoms are shown. The field free point is moved on a Lissajous trajectory inside a 30 × 30 mm2 area. Images of phantoms with a maximal distance of 10 mm perpendicular to the scanner surface have been reconstructed. Different cylindrically shaped holes of phantoms have been filled with 6.28 μl undiluted Resovist. After the measurement and image reconstruction of the phantoms, particle volumes could be distinguished with a distance of 2 mm and 6 mm in vertical and horizontal direction, respectively.
AB - Magnetic Particle Imaging is a new medical imaging modality, which detects superparamagnetic iron oxide nanoparticles. The particles are excited by magnetic fields. Most scanners have a tube-like measurement field and therefore, both the field of view and the object size are limited. A single-sided scanner has the advantage that the object is not limited in size, only the penetration depth is limited. A single-sided scanner prototype for 1D imaging has been presented in 2009. Simulations have been published for a 2D single-sided scanner and first 1D measurements have been carried out. In this paper, the first 2D single-sided scanner prototype is presented and the first calibration-based reconstruction results of measured 2D phantoms are shown. The field free point is moved on a Lissajous trajectory inside a 30 × 30 mm2 area. Images of phantoms with a maximal distance of 10 mm perpendicular to the scanner surface have been reconstructed. Different cylindrically shaped holes of phantoms have been filled with 6.28 μl undiluted Resovist. After the measurement and image reconstruction of the phantoms, particle volumes could be distinguished with a distance of 2 mm and 6 mm in vertical and horizontal direction, respectively.
UR - http://www.scopus.com/inward/record.url?scp=84963864468&partnerID=8YFLogxK
U2 - 10.1109/TMI.2015.2507187
DO - 10.1109/TMI.2015.2507187
M3 - Journal articles
C2 - 26701178
AN - SCOPUS:84963864468
SN - 0278-0062
VL - 35
SP - 1056
EP - 1065
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 4
M1 - 7360191
ER -