2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

Thorsten Simon; Barbara Hero; Johannes H. Schulte; Hedwig Deubzer; Patrick Hundsdoerfer; Dietrich Von Schweinitz; Jörg Fuchs; Matthias Schmidt; Vikas Prasad; Barbara Krug; Beate Timmermann; Ivo Leuschner; Matthias Fischer; Thorsten Langer; Kathy Astrahantseff; Frank Berthold; Holger Lode; Angelika Eggert

doi:10.1055/s-0043-103086

2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

Thorsten Simon^*, Barbara Hero, Johannes H. Schulte, Hedwig Deubzer, Patrick Hundsdoerfer, Dietrich Von Schweinitz, Jörg Fuchs, Matthias Schmidt, Vikas Prasad, Barbara Krug, Beate Timmermann, Ivo Leuschner, Matthias Fischer, Thorsten Langer, Kathy Astrahantseff, Frank Berthold, Holger Lode, Angelika Eggert

^*Corresponding author for this work

Clinic of Pediatric and Adolescent Medicine

18 Citations (Scopus)

Abstract

The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.

Original language	English
Journal	Klinische Padiatrie
Volume	229
Issue number	3
Pages (from-to)	147-167
Number of pages	21
ISSN	0300-8630
DOIs	https://doi.org/10.1055/s-0043-103086
Publication status	Published - 01.05.2017

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Simon, T., Hero, B., Schulte, J. H., Deubzer, H., Hundsdoerfer, P., Von Schweinitz, D., Fuchs, J., Schmidt, M., Prasad, V., Krug, B., Timmermann, B., Leuschner, I., Fischer, M., Langer, T., Astrahantseff, K., Berthold, F., Lode, H., & Eggert, A. (2017). 2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors. Klinische Padiatrie, 229(3), 147-167. https://doi.org/10.1055/s-0043-103086

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abstract = "The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.",

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Simon, T, Hero, B, Schulte, JH, Deubzer, H, Hundsdoerfer, P, Von Schweinitz, D, Fuchs, J, Schmidt, M, Prasad, V, Krug, B, Timmermann, B, Leuschner, I, Fischer, M, Langer, T, Astrahantseff, K, Berthold, F, Lode, H & Eggert, A 2017, '2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors', Klinische Padiatrie, vol. 229, no. 3, pp. 147-167. https://doi.org/10.1055/s-0043-103086

TY - JOUR

T1 - 2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

AU - Simon, Thorsten

AU - Hero, Barbara

AU - Schulte, Johannes H.

AU - Deubzer, Hedwig

AU - Hundsdoerfer, Patrick

AU - Von Schweinitz, Dietrich

AU - Fuchs, Jörg

AU - Schmidt, Matthias

AU - Prasad, Vikas

AU - Krug, Barbara

AU - Timmermann, Beate

AU - Leuschner, Ivo

AU - Fischer, Matthias

AU - Langer, Thorsten

AU - Astrahantseff, Kathy

AU - Berthold, Frank

AU - Lode, Holger

AU - Eggert, Angelika

PY - 2017/5/1

Y1 - 2017/5/1

N2 - The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.

AB - The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.

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SN - 0300-8630

VL - 229

SP - 147

EP - 167

JO - Klinische Padiatrie

JF - Klinische Padiatrie

IS - 3

ER -

2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

Abstract

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