γδ T-cells: Basic features and potential role in vasculitis

Dieter Kabelitz*, Juliane Fazio, Sabine Adam-Klages, Matthias Marget, Hans Heinrich Oberg, Daniela Wesch, Peter Lamprecht

*Corresponding author for this work
3 Citations (Scopus)

Abstract

γδ T-cells are a numerically small subset of T-cells with distinct features. They recognise antigens that are not seen by other immune cells. At the functional level, γδ T-cells share some features with αβ T-cells but also exert functions that are otherwise performed by specialised subsets of αβ T-cells (e.g. IL-17 production, regulatory activity). We discuss the potential role of γδ T-cells in various clinical forms of vasculitis.

Original languageEnglish
JournalClinical and Experimental Rheumatology
Volume28
Issue number1 SUPPL. 57
Pages (from-to)S104-S109
ISSN0392-856X
Publication statusPublished - 2010

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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