TY - JOUR
T1 - γδ T-cells: Basic features and potential role in vasculitis
AU - Kabelitz, Dieter
AU - Fazio, Juliane
AU - Adam-Klages, Sabine
AU - Marget, Matthias
AU - Oberg, Hans Heinrich
AU - Wesch, Daniela
AU - Lamprecht, Peter
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010
Y1 - 2010
N2 - γδ T-cells are a numerically small subset of T-cells with distinct features. They recognise antigens that are not seen by other immune cells. At the functional level, γδ T-cells share some features with αβ T-cells but also exert functions that are otherwise performed by specialised subsets of αβ T-cells (e.g. IL-17 production, regulatory activity). We discuss the potential role of γδ T-cells in various clinical forms of vasculitis.
AB - γδ T-cells are a numerically small subset of T-cells with distinct features. They recognise antigens that are not seen by other immune cells. At the functional level, γδ T-cells share some features with αβ T-cells but also exert functions that are otherwise performed by specialised subsets of αβ T-cells (e.g. IL-17 production, regulatory activity). We discuss the potential role of γδ T-cells in various clinical forms of vasculitis.
UR - http://www.scopus.com/inward/record.url?scp=77954588737&partnerID=8YFLogxK
M3 - Scientific review articles
C2 - 20412714
AN - SCOPUS:77954588737
SN - 0392-856X
VL - 28
SP - S104-S109
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
IS - 1 SUPPL. 57
ER -