The role of adiponectin in the regulation of hypothalamic circadian rhythms

Project: DFG ProjectsDFG Individual Projects

Project Details


Endogenous circadian clocks regulate physiology and behaviour along the 24-h day cycle. The circadian system and energy metabolism are tightly coupled. Central and peripheral circadian clocks coordinate key metabolic processes and the 24-h rhythms of food intake and energy expenditure. On the other hand, metabolic state can reset circadian rhythms in the periphery and the central nervous system - and in this way adapt physiological functions. The mechanisms of this metabolism-clock feedback will be studied in this project. We will use different transgenic mouse models to analyse the effect of adipose tissue-derived signals on circadian physiological and behavioural rhythms and clocks in energy metabolism-regulatory centres of the hypothalamus.
Effective start/end date01.01.1731.12.21

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 205-17 Endocrinology, Diabetology, Metabolism


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