CRU 111: Intersexuality - from gene to gender identity

  • Hiort, Olaf (Speaker, Coordinator)
  • Holterhus, Paul Martin (Co-Speaker)
  • Thyen, Ute (Principal Investigator (PI))
  • Richter-Appelt, Hertha (Principal Investigator (PI))

Project: DFG Joint Research › DFG Clinical Research Units (CRU)

Project Details

Description

Die Teilprojekte der Klinischen Forschergruppe 111 sind:

Bedeutung der Variabilität des polymorphen GGN-Wiederholungssegmentes und anderer Mutationen in der N-terminalen Domäne des humanen Androgenrezeptors für die differentielle Transaktivierung (Antragsteller Hiort, Olaf)

Bereitstellung von androgenen Steroidhormonen durch lokale enzymatische Regulation insbesondere durch 17beta-Hydroxysteroid Dehydrogenasen und deren Wertigkeit in der Geschlechtsdifferenzierung (Antragsteller Hiort, Olaf)

Charakterisierung von PBMC (peripheral blood mononuclear cells) als minimalinvasives Modell der individuellen Androgenrezeptorfunktion bei Androgenresistenz (Antragsteller Holterhus, Paul-Martin)

Genotyp-Phänotyp-Korrelation der Androgenresistenz durch Expressionsanalyse androgenregulierter Gene in Genitalhautfibroblasten per cDNA-Microarray (Antragsteller Holterhus, Paul-Martin)

Geschlechtsrollenverhalten, Geschlechtsidentität, sexuelle Orientierung und seelische Gesundheit bei Jugendlichen mit Androgenmangelsyndromen bei XY-Karyotyp (Antragstellerin Thyen, Ute)

Katamnestische Untersuchung bei erwachsenen Personen mit verschiedenen Formen der Intersexualität und bei Transsexuellen (Antragstellerin Richter-Appelt, Hertha)
Statusfinished
Effective start/end date01.01.01 → 31.12.06

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 5 - Gender Equality
  • SDG 10 - Reduced Inequalities

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 2.22-17 Endocrinology, Diabetology, Metabolism
  • 2.22-20 Pediatric and Adolescent Medicine

Funding Institution

  • DFG: German Research Association

ASJC Subject Areas

  • Endocrinology, Diabetes and Metabolism
  • Pediatrics, Perinatology, and Child Health

Project Details

  • SFB 1665: Sexdiversity - Determinants, meanings and implications of sex diversity in sociocultural, medical and biological landscapes

    Hiort, O. (Speaker, Coordinator), Rehmann-Sutter, C. (Co-Speaker), Aherrahrou, R. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Frielitz-Wagner, I. (Principal Investigator (PI)), Göpel, W. (Principal Investigator (PI)), Holterhus, P. M. (Principal Investigator (PI)), Hornig, N. C. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)), Jürgensen, M. (Principal Investigator (PI)), Kircher, M. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Krämer, U. (Principal Investigator (PI)), Kulle, A. E. (Principal Investigator (PI)), Laudes, M. (Principal Investigator (PI)), Mangold, A. K. (Principal Investigator (PI)), Malich, L. (Principal Investigator (PI)), Mittag, J. (Principal Investigator (PI)), Müller, F. J. (Principal Investigator (PI)), Nemec, B. (Principal Investigator (PI)), Palm, K. (Principal Investigator (PI)), Reisch, N. (Principal Investigator (PI)), Seeger, K. (Principal Investigator (PI)), Spielmann, M. (Principal Investigator (PI)), Stammberger, B. (Principal Investigator (PI)), Stoff, H. (Principal Investigator (PI)), Hines, M. (Scientific Advisor), Huebner, A. (Scientific Advisor), Wunn, C. (Scientific Advisor), Roggemann, E. (Scientific Advisor), Herrn, R. (Scientific Advisor), Sinclair, A. (Scientific Advisor), Villa Braslavsky, P.-I. (Scientific Advisor), Balachandran, S. (PostDoc), Mazukatow, A. (PostDoc), Scholz, J. (PostDoc), Steinbach, X. (PostDoc), Taege, N. (PostDoc), Wagemann, S. (PostDoc), Alnawasreh, B. (PhD Candidate), Ambrozini, L. (PhD Candidate), Blöbaum, L. (PhD Candidate), Chandra Prakash, S. A. (PhD Candidate), Dahl, A. (PhD Candidate), Denker, S. (PhD Candidate), Döhr, K. (PhD Candidate) & Egli, L. (PhD Candidate)

    01.02.24 → …

    Project: DFG Joint Research › DFG Collaborative Research Centers (CRC)

View all 2 projects