TH is of great importance for cardiac rhythmicity, as tachycardia is often observed in hyperthyroidism, while bradycardia is a leading symptom in hypothyroid patients. It is commonly assumed that the regulation of heart rate by TH is predominantly an effect of TH within the heart; however, recent studies showed that also central TH actions contribute to this phenotype. In the proposed project we now aim to dissect the local from the central actions of TH in the control of heart rate with a focus on the predominant receptor in heart and brain, TRα1.
|Effective start/end date||01.01.20 → …|
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
DFG Research Classification Scheme
- 205-17 Endocrinology, Diabetology
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