CRC/Transregio TRR 296 LocoTact, Project P03: Transporter expression and TH action in the brain

  • Biebermann, Heike (Principal Investigator (PI))
  • Bechmann, Ingo (Principal Investigator (PI))

Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

Project Details

Description

MCT8 is a specific TH transporter in the brain. In this project, spatiotemporal expression of MCT8 from early weeks of gestation to adult healthy and diseased human brains will be examined. In a complementary approach, we will develop MCT8 reporter stem cell models to monitor MCT8 expression during cerebral organoid differentiation and development and to enable enrichment of MCT8-expressing neuronal cell types for transcriptome analyses.
StatusActive
Effective start/end date01.01.20 → …

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 205-17 Endocrinology, Diabetology, Metabolism