Projects per year
Project Details
Description
MCT8 is a specific TH transporter in the brain. In this project, spatiotemporal expression of MCT8 from early weeks of gestation to adult healthy and diseased human brains will be examined. In a complementary approach, we will develop MCT8 reporter stem cell models to monitor MCT8 expression during cerebral organoid differentiation and development and to enable enrichment of MCT8-expressing neuronal cell types for transcriptome analyses.
| Status | Active |
|---|---|
| Effective start/end date | 01.01.20 → … |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
DFG Research Classification Scheme
- 2.22-17 Endocrinology, Diabetology, Metabolism
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Projects
- 1 Active
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CRC/Transregio TRR 296 LocoTact: Local control of TH action
Führer-Sakel, D. (Speaker, Coordinator), Mittag, J. (Second Speaker/Coordinator), Kühnen, P. (Second Speaker/Coordinator), Heuer, H. (Principal Investigator (PI)), Schwaninger, M. (Principal Investigator (PI)), Müller-Fielitz, H. (Principal Investigator (PI)), Bechmann, I. (Principal Investigator (PI)), Biebermann, H. (Principal Investigator (PI)), Müller, T. (Principal Investigator (PI)), Pfluger, P. (Principal Investigator (PI)), Krude, H. (Principal Investigator (PI)), Schülke-Gerstenfeld, M. (Principal Investigator (PI)), Cirkel, A. (Principal Investigator (PI)), Münte, T. (Principal Investigator (PI)), Kleinschnitz, C. (Principal Investigator (PI)), Langhauser, F. (Principal Investigator (PI)), Engel, D. R. (Principal Investigator (PI)), Möller, L. (Principal Investigator (PI)), Kaiser, F. (Principal Investigator (PI)), Oster, H. (Principal Investigator (PI)), Kirchner, H. (Principal Investigator (PI)), Spranger, J. (Principal Investigator (PI)), Tacke, F. (Principal Investigator (PI)), Wirth, E. K. (Principal Investigator (PI)), Köhrle, J. (Principal Investigator (PI)), Schomburg, L. (Principal Investigator (PI)), Lange, C. M. (Principal Investigator (PI)), Zwanziger, D. (Principal Investigator (PI)), Mayerl, S. (Principal Investigator (PI)) & Stachelscheid, H. (Principal Investigator (PI))
01.01.20 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios