CRC/Transregio TRR 240, Project B 04: Role of platelets in tissue remodelling and functional recovery after experimental cerebral ischaemia

  • Kleinschnitz, Christoph (Principal Investigator (PI))
  • Langer, Harald (Principal Investigator (PI))

Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

Project Details


In B04, we will assess whether platelets play a pathophysiological role during post-stroke recovery and late-stage tissue remodelling. The main focus will be on platelet-mediated thrombo-inflammation as well as potential extravascular effects of platelets, e.g. induction of apoptosis. Translationally meaningful mouse models, novel pharmacological inhibitors, and advanced imaging techniques will be used to investigate our research questions.
Effective start/end date01.01.1831.12.22

Collaborative partners

  • University of Würzburg (Joint applicant, Co-PI) (lead)


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