CRC/Transregio TRR 134, Project B01: Circadian clocks and hedonic appetite regulation

Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

Project Details


This project analyses the mechanisms of circadian regulation of homeostatic and reward systems in the context of appetite regulation. We hypothesize that mesolimbic and hypothalamic circadian clocks coordinate hedonic and homeostatic control aspects of appetite regulation and food uptake, respectively. Using genetic and pharmacologic manipulations in mice and human studies, we will analyse the interplay between local clock control at the level of central appetite circuits and systemic circadian endocrine signals such as glucocorticoids and metabolic peptides.
Effective start/end date01.01.1431.12.18

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 205-17 Endocrinology, Diabetology, Metabolism


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