CRC/Transregio TRR 134, Project A06: Inflammatory signalling in the regulation of feeding

  • Schwaninger, Markus (Principal Investigator (PI))
  • Wunderlich, Frank Thomas (Principal Investigator (PI))

Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

Project Details


The inflammatory mediators IL-6 and IL-1β inhibit aspects of hedonic and homeostatic control of food intake. Our previous work has shown that the effects of IL-6 and IL-1β are mediated by IL-6 transsignaling and astrocytic/tanycytic NF-κB signalling, respectively. Using a set of genetic, viral and in-vivo physiological tools that we have established in the first funding period, we will further characterize the cell types that are involved and will analyse the molecular mechanisms by which inflammatory mediators control food intake.
Effective start/end date01.01.1401.01.18

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 205-09 Pharmacology


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