Control-PD: Propagation of cognition in the prodromal phase of Parkinson's disease

Parkinson's disease often has a long precursor phase in which brain changes already exist and can lead to symptoms such as REM sleep behavior disorder, olfactory disorder or anxiety and depression. This consortium project aims to shed more light on the neurobiological processes within the brain. The study aims to link differences in the spread of the disease with abnormalities in cognition, affect and other symptoms that already occur during the precursor phase. The University of Lübeck is using computer-aided, model-based analyses and placing these in the context of brain structure and function. The findings could help to improve the prediction of the course of the disease. It is also conceivable that new treatment approaches could be established at a very early stage.