Research Output per year
Research Output per year
Personal profile
Scientific Focus
Shirin Emtenani received her M.Sc. degree in biochemistry from the Ferdowsi University of Mashhad (FUM), Iran, in 2013. In November 2014, she began her Ph.D. education at the Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Germany, and became associated to the DFG-funded Research Training Group 1727. In her Ph.D. thesis she investigated pathophysiologic mechanisms by cloning and comprehensive functional characterization of human autoantibodies in IgA-mediated pemphigus.
Following to her graduation in April 2019, she joined Prof. Dr. Enno Schmidt’s group (LIED, Division of Translational Research) as a postdoctoral researcher, where she continues to study various aspects of autoimmune skin disorders. Her research focuses on establishing in vivo models of pemphigus and pemphigoid diseases, for translational use for example in experimental therapeutic studies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
- Centers: Center for Research on Inflammation of the Skin (CRIS)
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Collaborations and top research areas from the last five years
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Bullous pemphigoid induced by IgG targeting type XVII collagen non-NC16A/NC15A extracellular domains is driven by Fc gamma receptor- and complement-mediated effector mechanisms and is ameliorated by neonatal Fc receptor blockade
Pigors, M., Patzelt, S., Reichhelm, N., Dworschak, J., Khil'chenko, S., Emtenani, S., Bieber, K., Hofrichter, M., Kamaguchi, M., Goletz, S., Köhl, G., Köhl, J., Komorowski, L., Probst, C., Vanderheyden, K., Balbino, B., Ludwig, R. J., Verheesen, P. & Schmidt, E., 02.2024, In: Journal of Pathology. 262, 2, p. 161-174 14 p.Research output: Journal Articles › Journal articles › Research › peer-review
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Laminin β4 is a constituent of the cutaneous basement membrane zone and additional autoantigen of anti-p200 pemphigoid
Goletz, S., Pigors, M., Lari, T. R., Hammers, C. M., Wang, Y., Emtenani, S., Aumailley, M., Holtsche, M. M., Stang, F. H., Weyers, I., König, I. R., Has, C., Radzimski, C., Komorowski, L., Zillikens, D. & Schmidt, E., 2023, In: Journal of the American Academy of Dermatology.Research output: Journal Articles › Journal articles › Research › peer-review
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Mouse models of pemphigus: valuable tools to investigate pathomechanisms and novel therapeutic interventions
Emtenani, S., Hertl, M., Schmidt, E. & Hudemann, C., 2023, In: Frontiers in Immunology. 14, p. 1169947 1169947.Research output: Journal Articles › Short survey › peer-review
3 Citations (Scopus) -
Corrigendum to: Cutaneous kinase activity correlates with treatment outcomes following PI3K delta inhibition in mice with experimental pemphigoid diseases, (Front. Immunol, (2022), 13, (865241), 10.3389/fimmu.2022.865241)
Ghorbanalipoor, S., Emtenani, S., Parker, M., Kamaguchi, M., Osterloh, C., Pigors, M., Gross, N., Khil’chenko, S., Kasprick, A., Patzelt, S., Wortmann, D., Ibrahim, I. O., Izumi, K., Goletz, S., Boch, K., Kalies, K., Bieber, K., Smith, P., Schmidt, E. & Ludwig, R. J., 30.11.2022, In: Frontiers in Immunology. 13, 1099535.Research output: Journal Articles › Comments/Debates
2 Citations (Scopus) -
Cutaneous kinase activity correlates with treatment outcomes following PI3K delta inhibition in mice with experimental pemphigoid diseases
Ghorbanalipoor, S., Emtenani, S., Parker, M., Kamaguchi, M., Osterloh, C., Pigors, M., Gross, N., Khil’chenko, S., Kasprick, A., Patzelt, S., Wortmann, D., Ibrahim, I. O., Izumi, K., Goletz, S., Boch, K., Kalies, K., Bieber, K., Smith, P., Schmidt, E. & Ludwig, R. J., 28.09.2022, In: Frontiers in Immunology. 13, 865241.Research output: Journal Articles › Journal articles › Research › peer-review
5 Citations (Scopus)