Research output per year
Research output per year
Personal profile
Scientific Focus
Model Systems of Inflammatory Skin Diseases
Our overall aim is the identification, validation and translation of novel therapeutic targets for the treatment of chronic inflammatory skin diseases.
Most projects focus on autoimmune skin blistering diseases, such as epidermolysis bullosa acquisita, bullous pemphigoid or pemphigus. In addition, we have established model systems for psoriasis, SLE and contact dermatitis.
We believe that cooperations with other academic centers and industry are the key to contribute to the high medical need to develop effective and save treatment options for patients affected by chronic skin inflammatory diseases. Please fell free to contact us if you are interested in our reagents or if you would like to start a cooperation.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
- Centers: Center for Research on Inflammation of the Skin (CRIS)
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Bullous pemphigoid induced by IgG targeting type XVII collagen non-NC16A/NC15A extracellular domains is driven by Fc gamma receptor- and complement-mediated effector mechanisms and is ameliorated by neonatal Fc receptor blockade
Pigors, M., Patzelt, S., Reichhelm, N., Dworschak, J., Khil'chenko, S., Emtenani, S., Bieber, K., Hofrichter, M., Kamaguchi, M., Goletz, S., Köhl, G., Köhl, J., Komorowski, L., Probst, C., Vanderheyden, K., Balbino, B., Ludwig, R. J., Verheesen, P. & Schmidt, E., 02.2024, In: Journal of Pathology. 262, 2, p. 161-174 14 p.Research output: Journal Articles › Journal articles › Research › peer-review
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A life for autoimmune blistering diseases: in memoriam Detlef Zillikens
Hundt, J. E., Sadik, C. D., van Beek, N., Busch, H., Caux, F., Goebeler, M., Hammers, C. M., Hartmann, K., Hashimoto, T., Ibrahim, S., Kasperkiewicz, M., Murrell, D. F., Recke, A., Rose, C., Schumacher, N., Shimanovich, I., Sitaru, C., Terheyden, P., Thaçi, D., Ludwig, R. J., & 1 others, 2023, In: Frontiers in Immunology. 14, 1291590.Research output: Journal Articles › Journal articles › Research › peer-review
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Association of Rituximab with Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients with Pemphigus
Kridin, K., Mruwat, N. & Ludwig, R. J., 18.01.2023, In: JAMA Dermatology. 159, 1, p. 56-61 6 p.Research output: Journal Articles › Journal articles › Research › peer-review
1 Citation (Scopus) -
Autoimmune pre-disease
Bieber, K., Hundt, J. E., Yu, X., Ehlers, M., Petersen, F., Karsten, C. M., Köhl, J., Kridin, K., Kalies, K., Kasprick, A., Goletz, S., Humrich, J. Y., Manz, R. A., Künstner, A., Hammers, C. M., Akbarzadeh, R., Busch, H., Sadik, C. D., Lange, T., Grasshoff, H., & 10 others, 02.2023, In: Autoimmunity Reviews. 22, 2, p. 103236 103236.Research output: Journal Articles › Scientific review articles › Research
1 Citation (Scopus) -
Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models
Lotti, R., Hundt, J. E., Ludwig, R. J., Bennett, B., Amato, A., Marconi, A. & Pincelli, C., 2023, In: Frontiers in Immunology. 14, p. 1193032 1193032.Research output: Journal Articles › Journal articles › Research › peer-review
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CRC 1526, Service Projects
Becker, M., Heine, G., Holtsche, M. M., Fähnrich, A., Szymczak, S., Ludwig, R. & Murthy, S.
01.01.22 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
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CRC 1526, Project A04: Selective B cell depletion in pemphigoid diseases by bispecific antibodies
Ludwig, R. & Peipp, M.
01.01.22 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
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CRC 1526, PANTAU: Pathomechanisms of Antibody-mediated Autoimmunity
Sadik, C., Zillikens, D., Scheffold, A., Schmidt, E., Heine, G., Manz, R., Köhl, J., Ludwig, R., Peipp, M., Hammers, M. C., Verschoor, A., Karsten, C., Nimmerjahn, F., Hutloff, A., Ibrahim, S., Wettschureck, N., Bieber, K., Schilf, P., Vaeth, M., Hirose, M., Vaeth, M., Baines, J. F., Bacher, P., Hoffmann, M., Busch, H. S., Höppner, M., Becker, M., Holtsche, M. M., Fähnrich, A., Szymczak, S., Murthy, S. & Lux, A.
01.01.22 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
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CRC 1526, Project B01: Site-specific inhibition of C5/C5a in pemphigoid diseases
Ludwig, R. & Peipp, M.
01.01.22 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
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Identification of novel therapeutic targets for the treatment of autoantibody-induced tissue pathology in pemphigus
01.01.22 → 31.12.26
Project: DFG Projects › DFG Individual Projects
Activities
- 1 Professional Society
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Arbeitsgemeinschaft Dermatologische Forschung (ADF) (External organisation)
Ralf Ludwig (Member)
2002 → …Activity: Membership types › Professional Society