Personal profile
Scientific Focus
Our group (LIGA for "Lübeck Interdisciplinary Platform for Genome Analytics") employs state-of-the-art high-throughput genome technologies to elucidate genetic and epigenetic determinants underlying aging-relevant traits and diseases, such as Alzheimer’s and Parkinson’s disease. To find out more about our research, please visit the LIGA website @ www.liga.uni-luebeck.de.
Research Areas and Centers
- Research Area: Medical Genetics
DFG Research Classification Scheme
- 2.23-06 Molecular and Cellular Neurology and Neuropathology
- 2.22-03 Human Genetics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease
Gauron, M. C., Prokopenko, D., Lee, S., Wolfe, S. A., Hecker, J., Willett, J., Waqas, M., Lordén, G., Yang, Y., Mayfield, J. E., Castanho, I., Mullin, K., Morgan, S., Hahn, G., Demeo, D. L., Hide, W., Bertram, L., Lange, C., Newton, A. C. & Tanzi, R. E., 01.07.2025, In: Science Signaling. 18, 893, eadv0970.Research output: Journal Articles › Journal articles › Research › peer-review
1 Link opens in a new tab Citation (Scopus)
Projects
- 6 Finished
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Development and validation of DNA-methylation clocks using longitudinal data from the Berlin Aging Study II (BASE-II)
Bertram, L. (Principal Investigator (PI)) & Demuth, I. (Principal Investigator (PI))
01.01.21 → 31.12.25
Project: DFG Individual Projects
Datasets
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Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning
Neumann, A. (Scientific Creator), Ohlei, O. (Scientific Creator), Küçükali, F. (Scientific Creator), Bos, I. J. (Scientific Creator), Timsina, J. (Scientific Creator), Vos, S. (Scientific Creator), Prokopenko, D. (Scientific Creator), Tijms, B. M. (Scientific Creator), Andreasson, U. (Scientific Creator), Blennow, K. (Scientific Creator), Vandenberghe, R. (Scientific Creator), Scheltens, P. (Scientific Creator), Teunissen, C. E. (Scientific Creator), Engelborghs, S. (Scientific Creator), Frisoni, G. B. (Scientific Creator), Blin, O. (Scientific Creator), Richardson, J. C. (Scientific Creator), Bordet, R. (Scientific Creator), Lleó, A. (Scientific Creator), Alcolea, D. (Scientific Creator), Popp, J. (Scientific Creator), Marsh, T. W. (Scientific Creator), Gorijala, P. (Scientific Creator), Clark, C. (Scientific Creator), Peyratout, G. (Scientific Creator), Martinez-Lage, P. (Scientific Creator), Tainta, M. (Scientific Creator), Dobson, R. J. B. (Scientific Creator), Legido-Quigley, C. (Scientific Creator), Van Broeckhoven, C. (Scientific Creator), Tanzi, R. E. (Scientific Creator), ten Kate, M. (Scientific Creator), Lill, C. M. (Scientific Creator), Barkhof, F. (Scientific Creator), Cruchaga, C. (Scientific Creator), Lovestone, S. (Scientific Creator), Streffer, J. (Scientific Creator), Zetterberg, H. (Scientific Creator), Visser, P. J. (Scientific Creator), Sleegers, K. (Scientific Creator) & Bertram, L. (Scientific Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.6866395.v1, https://springernature.figshare.com/collections/Multivariate_GWAS_of_Alzheimer_s_disease_CSF_biomarker_profiles_implies_GRIN2D_in_synaptic_functioning/6866395/1
Dataset