Research Output per year
Research Output per year
Personal profile
Scientific Focus
Our group (LIGA for "Lübeck Interdisciplinary Platform for Genome Analytics") employs state-of-the-art high-throughput genome technologies to elucidate genetic and epigenetic determinants underlying aging-relevant traits and diseases, such as Alzheimer’s and Parkinson’s disease. To find out more about our research, please visit the LIGA website @ www.liga.uni-luebeck.de.
Research Areas and Centers
- Research Area: Medical Genetics
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Collaborations and top research areas from the last five years
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A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets
Lee, S., Hahn, G., Hecker, J., Lutz, S. M., Mullin, K., Hide, W., Bertram, L., Demeo, D. L., Tanzi, R. E., Lange, C. & Prokopenko, D., 19.01.2023, In: Briefings in bioinformatics. 24, 1, 1.Research output: Journal Articles › Journal articles › Research › peer-review
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Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology
Delvenne, A., Gobom, J., Tijms, B., Bos, I., Reus, L. M., Dobricic, V., Kate, M. T., Verhey, F., Ramakers, I., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Schaeverbeke, J., Gabel, S., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Tsolaki, M. & Freund-Levi, Y. & 8 others, , 03.2023, In: Alzheimer's and Dementia. 19, 3, p. 807-820 14 p.Research output: Journal Articles › Journal articles › Research › peer-review
1 Citation (Scopus) -
Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease
Sommerer, Y., Dobricic, V., Schilling, M., Ohlei, O., Sabet, S. S., Wesse, T., Fuß, J., Franzenburg, S., Franke, A., Parkkinen, L., Lill, C. M. & Bertram, L., 06.05.2023, In: Alzheimer's Research and Therapy. 15, 1, p. 92 92.Research output: Journal Articles › Journal articles › Research › peer-review
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Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates
Nyberg, L., Andersson, M., Lundquist, A., Baaré, W. F. C., Bartrés-Faz, D., Bertram, L., Boraxbekk, C. J., Brandmaier, A. M., Demnitz, N., Drevon, C. A., Duezel, S., Ebmeier, K. P., Ghisletta, P., Henson, R., Jensen, D. E. A., Kievit, R. A., Knights, E., Kühn, S., Lindenberger, U. & Plachti, A. & 9 others, , 01.05.2023, In: Cerebral Cortex. 33, 9, p. 5075-5081 7 p.Research output: Journal Articles › Journal articles › Research › peer-review
2 Citations (Scopus) -
Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men
Algharably, E. A., Villagomez Fuentes, L. E., Toepfer, S., König, M., Regitz-Zagrosek, V., Bertram, L., Bolbrinker, J., Demuth, I. & Kreutz, R., 08.2023, In: Journal of Human Hypertension. 37, 8, p. 709-717 9 p.Research output: Journal Articles › Journal articles › Research › peer-review
1 Citation (Scopus)
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Development and validation of DNA-methylation clocks using longitudinal data from the Berlin Aging Study II (BASE-II)
Bertram, L. (Principal Investigator (PI)) & Demuth, I. (Principal Investigator (PI))
01.01.21 → 31.12.25
Project: DFG Projects › DFG Individual Projects
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RU 2488, Project: Identification of Penetrance- and Risk-Modifying Variants in Dystonia Using Different Genome-Wide Technologies
Bertram, L. (Principal Investigator (PI)) & Erdmann, J. (Principal Investigator (PI))
01.01.16 → …
Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units
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RU 2488, Project: Genetic Modifiers of Disease Penetrance and Expression in X-linked Dystonia-Parkinsonism
Bertram, L. (Principal Investigator (PI)) & Westenberger, A. (Principal Investigator (PI))
01.01.16 → …
Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units
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The role of microRNA-RNA regulatory networks in neural circuits affected by Alzheimer's disease
Bertram, L. (Principal Investigator (PI)) & Zhu, L.-Q. (Associated Staff)
01.01.18 → 31.12.22
Project: DFG Projects › DFG Individual Projects
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Genetic modifiers of disease expression in X-linked dystonia-parkinsonism
Bertram, L. (Principal Investigator (PI)) & Westenberger, A. (Principal Investigator (PI))
01.01.16 → 31.12.19
Project: DFG Projects › DFG Individual Projects