Inke Regina König

Research output

Research output per year 1997 2003 2005 2007 2008 2009 2011 2014 2018 2019 2020 2021 2022 2023 2024

• 329 Journal articles
• 25 Scientific review articles
• 12 Letters
• 9 Comments/Debates
• 13 More
  • 4 Editorial
  • 2 Chapter
  • 2 Short survey
  • 1 Books
  • 1 Conference contribution
  • 1 Conference Papers
  • 1 Newspaper articles
  • 1 Working papers

Research output per year

Research output per year

Search results

• 2005

  Querschnittsbereich quotedblbaseEpidemiologie, medizinische Biometrie und medizinische Informatiktextquotedblleft im Studiengang quotedblbaseHumanmedizintextquotedblleft der Universität zu Lübeck

  Ingenerf, J., König, I. R., Linder, R., Lühmann, D., Pöppl, S. J., Raspe, H. & Ziegler, A., 08.09.2005.

  Research output: Contribution to conference › Conference Papers › peer-review

• Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA

  Eggers, J., Seidel, G., Koch, B. & König, I. R., 22.03.2005, In: Neurology. 64, 6, p. 1052-1054 3 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Contraindications 100%
  • Stroke 69%
  • Middle Cerebral Artery Infarction 55%
  • Tissue Plasminogen Activator 54%
  • Acceleration 49%
  96 Citations (Scopus)
• 2004

  Age and National Institutes of Health Stroke Scale Score Within 6 Hours after Onset Are Accurate Predictors of Outcome after Cerebral Ischemia: Development and External Validation of Prognostic Models

  Weimar, C., König, I. R., Kraywinkel, K., Ziegler, A. & Diener, H. C., 01.2004, In: Stroke. 35, 1, p. 158-162 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • National Institutes of Health (U.S.) 100%
  • Brain Ischemia 95%
  • Stroke 65%
  • Clinical Trials 17%
  • Survival 15%
  310 Citations (Scopus)

• Analysis of SNPs in Pooled DNA: A Decision Theoretic Model

  König, I. R. & Ziegler, A., 01.2004, In: Genetic Epidemiology. 26, 1, p. 31-43 13 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Single Nucleotide Polymorphism 100%
  • Theoretical Models 96%
  • DNA 66%
  • Genotype 34%
  • Costs and Cost Analysis 29%
  5 Citations (Scopus)

• Anwendungsorientiertere Ausbildung im teil "medizinische biometrie" des Querschnittsfachs Q1 durch Einbettung von Konzepten der Evidenzbasierten Medizin - Ein Erfahrungsbericht nach Umstellung auf die neue ÄAppO

  Translated title of the contribution: More orientation on application in the course "medizinische biometrie" of the cross-sectional subject Q1 by including concepts of evidence-based medicineKönig, I. R., Repsilber, D., Dahmen, G., Kleensang, A. & Ziegler, A., 2004, In: Informatik Biometrie und Epidemiologie in Medizin und Biologie. 35, 4, p. 220-228 9 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • medicine 100%
  • evidence 57%
  • Schleswig-Holstein 32%
  • semester 31%
  • inferential statistics 24%
  2 Citations (Scopus)

• Auswirkungen der Qualität klinischer Studien in der Orthopädie und Unfallchirurgie auf den Erkenntnisstand.

  Translated title of the contribution: Impact of the quality of clinical trials in orthopedics and traumatology on the status of evidenceHaake, M., König, I. R. & Ziegler, A., 01.03.2004, In: Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V. 56, 1, p. 4-10 7 p.

  Research output: Journal Articles › Scientific review articles › Research

  • Traumatology 100%
  • Controlled Clinical Trials 81%
  • Orthopedics 67%
  • Clinical Trials 48%
  • Meta-Analysis 13%
  1 Citation (Scopus)

• Don't leave randomisation to chance

  König, I. R., Pahlke, F. & Ziegler, A., 10.2004, In: Good Clinical Practice Journal. 11, 10, p. 27-30 4 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  1 Citation (Scopus)

• Extended single nucleotide polymorphism and haplotype analysis of the elastin gene in Caucasians with intracranial aneurysms provides evidence for racially/ethnically based differences

  Krex, D., König, I. R., Ziegler, A., Schackert, H. K. & Schackert, G., 2004, In: Cerebrovascular Diseases. 18, 2, p. 104-110 7 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Elastin 100%
  • Intracranial Aneurysm 92%
  • Haplotypes 79%
  • Single Nucleotide Polymorphism 71%
  • Genes 34%
  30 Citations (Scopus)

• Extracorporeal Shock Wave Therapy for Lateral Epicondylitis

  Haake, M., Konig, I. R., Decker, T. & Trinh, K., 03.2004, In: Clinical Journal of Sport Medicine. 14, 2, p. 105-106 2 p.

  Research output: Journal Articles › Comments/Debates

• Matrix metalloproteinase-9 coding sequence single-nucleotide polymorphisms in Caucasians with intracranial aneurysms

  Krex, D., Kotteck, K., König, I. R., Ziegler, A., Schackert, H. K. & Schackert, G., 07.2004, In: Neurosurgery. 55, 1, p. 207-212 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Intracranial Aneurysm 100%
  • Matrix Metalloproteinase 9 98%
  • Single Nucleotide Polymorphism 77%
  • 3' Untranslated Regions 57%
  • Genotype 52%
  19 Citations (Scopus)

• Randomization In Treatment Arms (RITA): Ein Randomisierungs-Programm für klinische Studien

  Translated title of the contribution: Randomization In Treatment Arms (RITA): A randomization program for clinical trialsPahlke, F., König, I. R. & Ziegler, A., 2004, In: Informatik Biometrie und Epidemiologie in Medizin und Biologie. 35, 1, p. 1-22 22 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  22 Citations (Scopus)

• Sample size calculations for controlled clinical trials using generalized estimating equations (GEE)

  Dahmen, G., Rochon, J., König, I. R. & Ziegler, A., 2004, In: Methods of Information in Medicine. 43, 5, p. 451-456 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Controlled Clinical Trials 100%
  • Sample Size 81%
  • Clinical Trials 59%
  • Analysis of Variance 23%
  • Hypertension 19%
  30 Citations (Scopus)

• Spinocerebellar ataxia type 5: Clinical and molecular genetic features of a German kindred

  Bürk, K., Zühlke, C., König, I. R., Ziegler, A., Schwinger, E., Globas, C., Dichgans, J. & Hellenbroich, Y., 27.01.2004, In: Neurology. 62, 2, p. 327-329 3 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Lod Score 100%
  • Spinocerebellar Ataxias 95%
  • Cerebellar Diseases 93%
  • Cerebellar Ataxia 88%
  • Age of Onset 66%
  49 Citations (Scopus)

• Variations in the genes encoding the peroxisome proliferator-activated receptors α and γ in psoriasis

  Mössner, R., Kaiser, R., Matern, P., Krüger, U., Westphal, G. A., Brockmöller, J., Ziegler, A., Neumann, C., König, I. R. & Reich, K., 06.2004, In: Archives of Dermatological Research. 296, 1, p. 1-5 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Peroxisome Proliferator-Activated Receptors 100%
  • Psoriasis 81%
  • Genes 33%
  • Keratinocytes 17%
  • Ligands 12%
  17 Citations (Scopus)
• 2003

  Accelerating trials by flexible design

  Ziegler, A., Dahmen, G., König, I. R., Wassmer, G., Hildebrand, P. & Birth, M., 12.2003, In: Good Clinical Practice Journal. 10, 12, p. 16-19 4 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Controlled Clinical Trials 100%
  • Clinical Trials 59%

• Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene

  Reich, K., Westphal, G., König, I. R., Mössner, R., Krüger, U., Ziegler, A., Neumann, C. & Schnuch, A., 12.2003, In: Journal of Allergy and Clinical Immunology. 112, 6, p. 1191-1194 4 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Interleukin-16 100%
  • Allergic Contact Dermatitis 81%
  • Atopic Dermatitis 38%
  • Genes 25%
  • Genotype 19%
  84 Citations (Scopus)

• Candidate gene studies in focal dystonia

  Sibbing, D., Asmus, F., König, I. R., Tezenas Du Montcel, S., Vidailhet, M., Sangla, S., Oertel, W. H., Brice, A., Ziegler, A., Gasser, T. & Bandmann, O., 28.10.2003, In: Neurology. 61, 8, p. 1097-1101 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Dystonia Musculorum Deformans 100%
  • Dystonic Disorders 81%
  • Dichlororibofuranosylbenzimidazole 25%
  • Genes 23%
  • Homocysteine 18%
  37 Citations (Scopus)

• Cytokine gene polymorphisms in allergic contact dermatitis

  Westphal, G. A., Schnuch, A., Moessner, R., König, I. R., Kränke, B., Hallier, E., Ziegler, A. & Reich, K., 01.02.2003, In: Contact Dermatitis. 48, 2, p. 93-98 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Allergic Contact Dermatitis 100%
  • Eczema 60%
  • Genotype 56%
  • Cytokines 48%
  • Hypersensitivity 42%
  101 Citations (Scopus)

• Cytokine gene polymorphisms in atopic dermatitis

  Reich, K., Westphal, G., König, I. R., Mössner, R., Schupp, P., Gutgesell, C., Hallier, E., Ziegler, A. & Neumann, C., 01.06.2003, In: British Journal of Dermatology. 148, 6, p. 1237-1241 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Atopic Dermatitis 100%
  • Cytokines 59%
  • Psoriasis 47%
  • Genes 38%
  • Skin 19%
  45 Citations (Scopus)

• Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

  Eggers, J., Koch, B., Meyer, K., König, I. & Scidel, G., 01.06.2003, In: Annals of Neurology. 53, 6, p. 797-800 4 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Middle Cerebral Artery Infarction 100%
  • Tissue Plasminogen Activator 24%
  • Doppler Ultrasonography 23%
  • Stroke 15%
  • Hemorrhage 14%
  136 Citations (Scopus)

• Extracorporeal shock wave therapy in the treatment of lateral epicondylitis [6] (multiple letters)

  Johnson, D., Haake, M., König, I. R., Decker, T., Riedel, C., Buch, M. & Müller, H. H., 01.07.2003, In: Journal of Bone and Joint Surgery - Series A. 85, 7, p. 1392-1394 3 p.

  Research output: Journal Articles › Letters › peer-review

• Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR)

  Fitze, G., Appelt, H., König, I. R., Stein, U., Walther, W., Gossen, M., Schreiber, M., Ziegler, A., Roesner, D. & Schackert, H. K., 15.12.2003, In: Human Molecular Genetics. 12, 24, p. 3207-3214 8 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Hirschsprung Disease 100%
  • Proto-Oncogenes 90%
  • Haplotypes 72%
  • Germ-Line Mutation 19%
  • Luciferases 16%
  66 Citations (Scopus)

• Group sequential study designs in genetic-epidemiological case-control studies

  König, I. R. & Ziegler, A., 2003, In: Human Heredity. 56, 1-3, p. 63-72 10 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Sample Size 100%
  • Case-Control Studies 90%
  • Viverridae 39%
  • Multifactorial Inheritance 34%
  • Epidemiologic Studies 23%
  12 Citations (Scopus)

• HLA-DRB genotyping in Gilles de la Tourette patients and their parents

  Schoenian, S., Konig, I., Oertel, W., Remschmidt, H., Ziegler, A., Hebebrand, J. & Bandmann, O., 15.05.2003, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 119 B, 1, p. 60-64 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Dichlororibofuranosylbenzimidazole 100%
  • HLA Antigens 69%
  • Parents 50%
  • Alleles 49%
  • Genetic Predisposition to Disease 27%
  13 Citations (Scopus)

• Novel genetic variation of human interleukin-21 receptor is associated with elevated IgE levels in females

  Hecker, M., Bohnert, A., König, I. R., Bein, G. & Hackstein, H., 04.2003, In: Genes and Immunity. 4, 3, p. 228-233 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • human IL21R protein 100%
  • Interleukin-21 Receptors 74%
  • Genetic Variation 41%
  • Immunoglobulin E 39%
  • 5' Flanking Region 20%
  32 Citations (Scopus)

• Polymorphisms of the NADPH oxidase p22phox gene in a Caucasian population with intracranial aneurysms

  Krex, D., Ziegler, A., König, I. R., Schackert, H. K. & Schackert, G., 2003, In: Cerebrovascular Diseases. 16, 4, p. 363-368 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • NADPH Oxidases 100%
  • Intracranial Aneurysm 94%
  • Cerebrovascular Disorders 45%
  • Atherosclerosis 35%
  • Genes 35%
  27 Citations (Scopus)

• Reducing Sample Sizes in Genome Scans: Group Sequential Study Designs with Futility Stops

  König, I. R., Schäfer, H., Ziegler, A. & Müller, H. H., 12.2003, In: Genetic Epidemiology. 25, 4, p. 339-349 11 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Medical Futility 100%
  • Sample Size 63%
  • Genome 48%
  • Viverridae 20%
  • Genetic Linkage 18%
  8 Citations (Scopus)

• Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine

  Theisen, F. M., Linden, A., König, I. R., Martin, M., Remschmidt, H. & Hebebrand, J., 01.01.2003, In: Journal of Neural Transmission. 110, 1, p. 111-121 11 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Bulimia 100%
  • Olanzapine 98%
  • Clozapine 95%
  • Feeding and Eating Disorders 34%
  • Weight Gain 29%
  84 Citations (Scopus)

• Tissue Inhibitor of Metalloproteinases-1, -2, and -3 Polymorphisms in a White Population with Intracranial Aneurysms

  Krex, D., Röhl, H., König, I. R., Ziegler, A., Schackert, H. K. & Schackert, G., 12.2003, In: Stroke. 34, 12, p. 2817-2821 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-2 100%
  • Tissue Inhibitor of Metalloproteinase-1 92%
  • Intracranial Aneurysm 83%
  • Tissue Inhibitor of Metalloproteinase-3 45%
  • Extracellular Matrix 39%
  42 Citations (Scopus)

• Vorhersage des Funktionsstatus 100 Tage nach einem ischämischen Schlaganfall: Design einer prospektiven Studie zur Externen Validierung eines Prognostischen Modells

  Translated title of the contribution: Predicted Functional Outcome 100 Days after Ischaemic Stroke: Design of a Prospective Study about the External Validation of a Prognostic ModelKönig, I. R., Weimar, C., Diener, H. C. & Ziegler, A., 12.2003, In: Zeitschrift fur Arztliche Fortbildung und Qualitatssicherung. 97, 10, p. 717-722 6 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Stroke 100%
  • Prospective Studies 93%
  • Multicenter Studies 42%
  • Datasets 38%
  • Clinical Trials 31%
  7 Citations (Scopus)
• 2002

  Extracorporeal shock wave therapy in the treatment of lateral epicondylitis: A randomized multicenter trial

  Haake, M., König, I. R., Decker, T., Riedel, C., Buch, M. & Müller, H. H., 01.11.2002, In: Journal of Bone and Joint Surgery - Series A. 84, 11, p. 1982-1991 10 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Tennis Elbow 100%
  • Extracorporeal Shockwave Therapy 96%
  • Multicenter Studies 59%
  • Local Anesthesia 27%
  • Placebos 17%
  142 Citations (Scopus)

• Extrakorporale stoßwellentherapie (ESWT) bei epicondylitis humeri radialis. Eine literaturübersicht

  Translated title of the contribution: Extracorporeal shock wave therapy (ESWT) for lateral epicondylitis. A reviewHaake, M., Hünerkopf, M., Gerdesmeyer, L. & König, I. R., 2002, In: Orthopade. 31, 7, p. 623-632 10 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Tennis Elbow 100%
  • Extracorporeal Shockwave Therapy 96%
  • Control Groups 10%
  • Local Anesthetics 10%
  • Placebos 6%
  7 Citations (Scopus)

• Large-scale determination of SNP allele frequencies in DNA pools using MALDI-TOF mass spectrometry

  Werner, M., Sych, M., Herbon, N., Illig, T., König, I. R. & Wjst, M., 2002, In: Human Mutation. 20, 1, p. 57-64 8 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Gene Frequency 100%
  • Mass Spectrometry 92%
  • Single Nucleotide Polymorphism 85%
  • Lasers 82%
  • DNA 57%
  78 Citations (Scopus)

• Predicting functional outcome and survival after acute ischemic stroke

  Weimar, C., Ziegler, A., König, I. R. & Diener, H. C., 2002, In: Journal of Neurology. 249, 7, p. 888-895 8 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Stroke 100%
  • Survival 81%
  • Fever 21%
  • Validation Studies 16%
  • Paresis 15%
  254 Citations (Scopus)

• Promoter polymorphisms of the genes encoding tumor necrosis factor-α and interleukin-1β are associated with different subtypes of psoriasis characterized by early and late disease onset

  Reich, K., Mössner, R., König, I. R., Westphal, G., Ziegler, A. & Neumann, C., 01.2002, In: Journal of Investigative Dermatology. 118, 1, p. 155-163 9 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Late Onset Disorders 100%
  • Interleukin-1 74%
  • Psoriasis 73%
  • Tumor Necrosis Factor-alpha 53%
  • Interleukin-1 Receptors 44%
  100 Citations (Scopus)
• 2001

  Optimized group sequential study designs for tests of genetic linkage and association in complex diseases

  König, I. R., Schäfer, H., Müller, H. H. & Ziegler, A., 2001, In: American Journal of Human Genetics. 69, 3, p. 590-600 11 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • Genetic Linkage 100%
  • Sample Size 68%
  • Multifactorial Inheritance 15%
  • Costs and Cost Analysis 7%
  18 Citations (Scopus)
• 1997

  Iron reduction through the tan-green color transition in deep-sea sediments

  König, I., Drodt, M., Suess, E. & Trautwein, A. X., 01.04.1997, In: Geochimica et Cosmochimica Acta. 61, 8, p. 1679-1683 5 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • deep-sea sediment 100%
  • iron 54%
  • transition 51%
  • transition zone 40%
  • deep sea 19%
  42 Citations (Scopus)

• Mössbauer spectroscopic studies on the iron forms of deep-sea sediments

  Drodt, M., Trautwein, A. X., König, I., Suess, E. & Bender Koch, C., 01.01.1997, In: Physics and Chemistry of Minerals. 24, 4, p. 281-293 13 p.

  Research output: Journal Articles › Journal articles › Research › peer-review

  • deep-sea sediment 100%
  • iron 54%
  • sediment 39%
  • goethite 37%
  • hematite 34%
  21 Citations (Scopus)