• 1135
    Citations
20092021

Research activity per year

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Search results

  • 2021

    A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

    Wierer, M., Werner, J., Wobst, J., Kastrati, A., Cepele, G., Aherrahrou, R., Sager, H. B., Erdmann, J., Dichgans, M., Flockerzi, V., Civelek, M., Dietrich, A., Mann, M., Schunkert, H. & Kessler, T., 07.05.2021, In: European Heart Journal. 42, 18, p. 1773-1785 13 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    2 Citations (Scopus)
  • Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family

    Dang, T. A., Kessler, T., Wobst, J., Wierer, M., Braenne, I., Strom, T. M., Tennstedt, S., Sager, H. B., Meitinger, T., Erdmann, J. & Schunkert, H., 23.08.2021, In: Circulation. p. 662-665 4 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    1 Citation (Scopus)
  • 2020

    Hospital admissions with acute coronary syndromes during the COVID-19 pandemic in German cardiac care units

    Kessler, T., Graf, T., Hilgendorf, I., Rizas, K., Martens, E., von zur Mühlen, C., Kraemer, P., Meyer-Saraei, R., Neumann, F. J., Bode, C., Laugwitz, K. L., Massberg, S., Schunkert, H., Weil, J., Kastrati, A. & Sager, H. B., 01.09.2020, In: Cardiovascular Research. 116, 11, p. 1800-1801 2 p.

    Research output: Journal ArticlesLetterspeer-review

  • SARS-CoV-2 Infection in Asymptomatic Patients Hospitalized for Cardiac Emergencies: Implications for Patient Management

    Kessler, T., Wiebe, J., Graf, T., Schunkert, H., Kastrati, A. & Sager, H. B., 2020, In: Frontiers in Cardiovascular Medicine. 7, p. 599299

    Research output: Journal ArticlesJournal articlesResearchpeer-review

  • 2019

    Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention

    Kessler, T., Wolf, B., Eriksson, N., Kofink, D., Mahmoodi, B. K., Rai, H., Tragante, V., Åkerblom, A., Becker, R. C., Bernlochner, I., Bopp, R., James, S., Katus, H. A., Mayer, K., Munz, M., Nordio, F., O'Donoghue, M. L., Sager, H. B., Sibbing, D., Solakov, L., & 11 othersStorey, R. F., Wobst, J., Asselbergs, F. W., Byrne, R. A., Erdmann, J., Koenig, W., Laugwitz, K. L., Ten Berg, J. M., Wallentin, L., Kastrati, A. & Schunkert, H., 2019, In: Cardiovascular Research. 115, 10, p. 1512-1518 7 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    7 Citations (Scopus)
  • 2017

    Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus

    Kessler, T., Wobst, J., Wolf, B., Eckhold, J., Vilne, B., Hollstein, R., Von Ameln, S., Dang, T. A., Sager, H. B., Rumpf, P. M., Aherrahrou, R., Kastrati, A., Björkegren, J. L. M., Erdmann, J., Lusis, A. J., Civelek, M., Kaiser, F. J. & Schunkert, H., 01.08.2017, In: Circulation. 136, 5, p. 476-489 14 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    3 Citations (Scopus)
  • 2016

    Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism

    Kessler, T., Erdmann, J., Vilne, B., Bruse, P., Kurowski, V., Diemert, P., Schunkert, H. & Sager, H. B., 05.05.2016, In: Journal of Translational Medicine. 14, 1, 120.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    6 Citations (Scopus)
  • Stimulators of the soluble guanylyl cyclase: promising functional insights from rare coding atherosclerosis-related GUCY1A3 variants

    Wobst, J., von Ameln, S., Wolf, B., Wierer, M., Dang, T. A., Sager, H. B., Tennstedt, S., Hengstenberg, C., Koesling, D., Friebe, A., Braun, S. L., Erdmann, J., Schunkert, H. & Kessler, T., 01.07.2016, In: Basic Research in Cardiology. 111, 4, 51.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    3 Citations (Scopus)
  • 2014

    Single nucleotide polymorphisms with Cis-regulatory effects on long non-coding transcripts in human primary monocytes

    Almlöf, J. C., Lundmark, P., Lundmark, A., Ge, B., Pastinen, T., Goodal, A. H., Cambien, F., Deloukas, P., Ouwehand, W. H., Syvänen, A. C., Schunkert, H., Attwood, T., Belz, S., Braund, P., Brocheton, J., Cooper, J., Crisp-Hihn, A., Diemert, P., Erdmann, J., Foad, N., & 34 othersGodefroy, T., Gracey, J., Gray, E., Gwilliams, R., Heimerl, S., Hengstenberg, C., Jolley, J., Krishnan, U., Lloyd-Jones, H., Liljedahl, U., Lugauer, I., Maouche, S., Moore, J. S., Montalescot, G., Muir, D., Murray, E., Nelson, C. P., Neudert, J., Niblett, D., O'Leary, K., Pollard, H., Proust, C., Rankin, A., Rendon, A., Rice, C. M., Sager, H., Samani, N. J., Sambrook, J., Schmitz, G., Scholz, M., Schroeder, L., Stephens, J., Tennstedt, S. & Wallace, C., 15.07.2014, In: PLoS ONE. 9, 7, e102612.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    7 Citations (Scopus)
  • 2013

    Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

    DIAGRAM Consortium, Randall, J. C., Winkler, T. W., Kutalik, Z., Berndt, S. I., Jackson, A. U., Monda, K. L., Kilpeläinen, T. O., Esko, T., Mägi, R., Li, S., Workalemahu, T., Feitosa, M. F., Croteau-Chonka, D. C., Day, F. R., Fall, T., Ferreira, T., Gustafsson, S., Locke, A. E., Mathieson, I., & 31 othersScherag, A., Vedantam, S., Wood, A. R., Liang, L., Steinthorsdottir, V., Thorleifsson, G., Dermitzakis, E. T., Dimas, A. S., Karpe, F., Min, J. L., Nicholson, G., Clegg, D. J., Person, T., Krohn, J. P., Bauer, S., Buechler, C., Eisinger, K., Bonnefond, A., Froguel, P., Hottenga, J-J., Prokopenko, I., Waite, L. L., Harris, T. B., Smith, A. V., Shuldiner, A. R., McArdle, W. L., Caulfield, M. J., Erdmann, J., Loley, C., Schunkert, H. & Sager, H., 06.2013, In: PLoS Genetics. 9, 6, p. e1003500

    Research output: Journal ArticlesJournal articlesResearchpeer-review

  • 2012

    Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression

    Greliche, N., Zeller, T., Wild, P. S., Rotival, M., Schillert, A., Ziegler, A., Deloukas, P., Erdmann, J., Hengstenberg, C., Ouwehand, W. H., Samani, N. J., Schunkert, H., Munzel, T., Lackner, K. J., Cambien, F., Goodall, A. H., Tiret, L., Blankenberg, S., Trégouët, D. A., Attwood, T., & 41 othersStephanie, B., Braund, P., Brocheton, J., Cooper, J., Crisp-Hihn, A., Diemert, P., Foad, N., Godefroy, T., Gracey, J., Gray, E., Gwilliams, R., Heimerl, S., Jolley, J., Krishnan, U., Lloyd-Jones, H., Liljedahl, U., Lugauer, I., Lundmark, P., Maouche, S., Moore, J. S., Gilles, M., Muir, D., Murray, E., Nelson, C. P., Neudert, J., Niblett, D., O'Leary, K., Pollard, H., Proust, C., Rankin, A., Rendon, A., Rice, C. M., Sager, H., Sambrook, J., Gerd, S., Scholz, M., Schroeder, L., Stephens, J., Syvannen, A. C., Tennstedt, S. & Wallace, C., 21.09.2012, In: PLoS ONE. 7, 9, e45863.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    8 Citations (Scopus)
  • 2011

    A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

    Wild, P. S., Zeller, T., Schillert, A., Szymczak, S., Sinning, C. R., Deiseroth, A., Schnabel, R. B., Lubos, E., Keller, T., Eleftheriadis, M. S., Bickel, C., Rupprecht, H. J., Wilde, S., Rossmann, H., Diemert, P., Cupples, L. A., Perret, C., Erdmann, J., Stark, K., Kleber, M. E., & 69 othersEpstein, S. E., Voight, B. F., Kuulasmaa, K., Li, M., Schäfer, A. S., Klopp, N., Braund, P. S., Sager, H. B., Demissie, S., Proust, C., König, I. R., Wichmann, H. E., Reinhard, W., Hoffmann, M. M., Virtamo, J., Burnett, M. S., Siscovick, D., Wiklund, P. G., Qu, L., El Mokthari, N. E., Thompson, J. R., Peters, A., Smith, A. V., Yon, E., Baumert, J., Hengstenberg, C., März, W., Amouyel, P., Devaney, J., Schwartz, S. M., Saarela, O., Mehta, N. N., Rubin, D., Silander, K., Hall, A. S., Ferrieres, J., Harris, T. B., Melander, O., Kee, F., Hakonarson, H., Schrezenmeir, J., Gudnason, V., Elosua, R., Arveiler, D., Evans, A., Rader, D. J., Illig, T., Schreiber, S., Bis, J. C., Altshuler, D., Kavousi, M., Witteman, J. C. M., Uitterlinden, A. G., Hofman, A., Folsom, A. R., Barbalic, M., Boerwinkle, E., Kathiresan, S., Reilly, M. P., O'Donnell, C. J., Samani, N. J., Schunkert, H., Cambien, F., Lackner, K. J., Tiret, L., Salomaa, V., Munzel, T., Ziegler, A. & Blankenberg, S., 01.08.2011, In: Circulation: Cardiovascular Genetics. 4, 4, p. 403-412 10 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    77 Citations (Scopus)
  • Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23

    Erdmann, J., Willenborg, C., Nahrstaedt, J., Preuss, M., König, I. R., Baumert, J., Linsel-Nitschke, P., Gieger, C., Tennstedt, S., Belcredi, P., Aherrahrou, Z., Klopp, N., Loley, C., Stark, K., Hengstenberg, C., Bruse, P., Freyer, J., Wagner, A. K., Medack, A., Lieb, W., & 20 othersGroßhennig, A., Sager, H. B., Reinhardt, A., Schäfer, A., Schreiber, S., El Mokhtari, N. E., Raaz-Schrauder, D., Illig, T., Garlichs, C. D., Ekici, A. B., Reis, A., Schrezenmeir, J., Rubin, D., Ziegler, A., Wichmann, H. E., Doering, A., Meisinger, C., Meitinger, T., Peters, A. & Schunkert, H., 01.01.2011, In: European Heart Journal. 32, 2, p. 158-168 11 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    58 Citations (Scopus)
  • Large-scale gene-centric analysis identifies novel variants for coronary artery disease

    Butterworth, A. S., Braund, P. S., Farrall, M., Hardwick, R. J., Saleheen, D., Peden, J. F., Soranzo, N., Chambers, J. C., Sivapalaratnam, S., Kleber, M. E., Keating, B., Qasim, A., Klopp, N., Erdmann, J., Assimes, T. L., Ball, S. G., Balmforth, A. J., Barnes, T. A., Basart, H., Baumert, J., & 333 othersBezzina, C. R., Boerwinkle, E., Boehm, B. O., Brocheton, J., Bugert, P., Cambien, F., Clarke, R., Codd, V., Collins, R., Couper, D., Adrienne Cupples, L., de Jong, J. S., Diemert, P., Ejebe, K., Elbers, C. C., Elliott, P., Fornage, M., Franzosi, M. G., Frossard, P., Garner, S., Goel, A., Goodall, A. H., Hengstenberg, C., Hunt, S. E., Kastelein, J. J. P., Klungel, O. H., Klüterr, H., Koch, K., König, I. R., Kooner, A. S., Laaksonen, R., Lathrop, M., Li, M., Liu, K., McPherson, R., Musameh, M. D., Musani, S., Nelson, C. P., O'Donnell, C. J., Ongen, H., Papanicolaou, G., Peters, A., Peters, B. J. M., Potter, S., Psaty, B. M., Qu, L., Rader, D. J., Rasheed, A., Rice, C., Scott, J., Seedorf, U., Sehmi, J. S., Sotoodehnia, N., Stark, K., Stephens, J., van der Schoot, C. E., van der Schouw, Y. T., Thorsteinsdottir, U., Tomaszewski, M., van der Harst, P., Vasan, R. S., Wilde, A. A. M., Willenborg, C., Winkelmann, B. R., Zaidi, M., Zhang, W., Ziegler, A., de Bakker, P. I. W., Koenig, W., März, W., Trip, M. D., Reilly, M. P., Kathiresan, S., Schunkert, H., Hamsten, A., Hall, A. S., Kooner, J. S., Thompson, S. G., Thompson, J. R., Deloukas, P., Ouwehand, W. H., Watkins, H., Danesh, J., Samani, N. J., Barnes, T., Rafelt, S., Bruinsma, N., Dekker, L. R., Henriques, J. P., Koch, K. T., de Winter, R. J., Alings, M., Allaart, C. F., Gorgels, A. P., Verheugt, F. W., Samani, N. J., Mueller, M., Meisinger, C., DerOhannessian, S., Mehta, N. N., Ferguson, J., Hakonarson, H., Matthai, W., Wilensky, R., Hopewell, J. C., Parish, S., Linksted, P., Notman, J., Gonzalez, H., Young, A., Ostley, T., Munday, A., Goodwin, N., Verdon, V., Shah, S., Cobb, L., Edwards, C., Mathews, C., Gunter, R., Benham, J., Davies, C., Cobb, M., Crowther, J., Richards, A., Silver, M., Tochlin, S., Mozley, S., Clark, S., Radley, M., Kourellias, K., Olsson, P., Barlera, S., Tognoni, G., Rust, S., Assmann, G., Heath, S., Zelenika, D., Gut, I., Green, F., Peden, J., Aly, A., Anner, K., Björklund, K., Blomgren, G., Cederschiöld, B., Danell-Toverud, K., Eriksson, P., Grundstedt, U., Heinonen, M., Hellénius, M. L., van't Hooft, F., Husman, K., Lagercrantz, J., Larsson, A., Larsson, M., Mossfeldt, M., Mälarstig, A., Olsson, G., Sabater-Lleal, M., Sennblad, B., Silveira, A., Strawbridge, R., Söderholm, B., Öhrvik, J., Shah Zaman, K., Hayat Mallick, N., Azhar, M., Samad, A., Ishaq, M., Shah, N., Samuel, M., Reilly, M., Holm, H., Preuss, M., Stewart, A. F. R., Barbalic, M., Gieger, C., Absher, D., Aherrahrou, Z., Allayee, H., Altshuler, D., Anand, S., Andersen, K., Anderson, J. L., Ardissino, D., Becker, L. C., Becker, D. M., Berger, K., Bis, J. C., Matthijs Boekholdt, S., Brown, M. J., Susan Burnett, M., Buysschaert, I., Carlquist, J. F., Chen, L., Davies, R. W., Dedoussis, G., Dehghan, A., Demissie, S., Devaney, J., Do, R., Doering, A., El Mokhtari, N. E., Ellis, S. G., Elosua, R., Engert, J. C., Epstein, S., de Faire, U., Fischer, M., Folsom, A. R., Freyer, J., Gigante, B., Girelli, D., Gretarsdottir, S., Gudnason, V., Gulcher, J. R., Tennstedt, S., Halperin, E., Hammond, N., Hazen, S. L., Hofman, A., Horne, B. D., Illig, T., Iribarren, C., Jones, G. T., Wouter Jukema, J., Kaiser, M. A., Kaplan, L. M., Khaw, K. T., Knowles, J. W., Kolovou, G., Kong, A., Lambrechts, D., Leander, K., Lieb, W., Lettre, G., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meitinger, T., Melander, O., Angelica Merlini, P., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Musunuru, K., Nahrstaedt, J., Nöthen, M. M., Olivieri, O., Peyvandi, F., Patel, R. S., Patterson, C. C., Quyyumi, A. A., Rallidis, L. S., Roosendaal, F. R., Rubin, D., Salomaa, V., Lourdes Sampietro, M., Sandhu, M. S., Schadt, E., Schäfer, A., Schillert, A., Schreiber, S., Schrezenmeir, J., Schwartz, S. M., Siscovick, D. S., Sivananthan, M., Smith, A. V., Smith, T. B., Snoep, J. D., Spertus, J. A., Stefansson, K., Stirrups, K., Stoll, M., Wilson Tang, W. H., Thorgeirsson, G., Thorleifsson, G., Uitterlinden, A. G., van Rij, A. M., Voight, B. F., Wareham, N. J., Wells, G. A., Wichmann, H. E., Witteman, J. C. M., Wright, B. J., Ye, S., Quertermous, T., Blankenberg, S., Roberts, R., Onland-Moret, N. C., van Setten, J., Monique Verschuren, W. M., Boer, J. M. A., Wijmenga, C., Hofker, M. H., Maitland-van der Zee, A. H., de Boer, A., Grobbee, D. E., Attwood, T., Belz, S., Braund, P., Cooper, J., Crisp-Hihn, A., Foad, N., Gracey, J., Gray, E., Gwilliams, R., Heimerl, S., Jolley, J., Krishnan, U., Lloyd-Jones, H., Lugauer, I., Lundmark, P., Moore, J. S., Muir, D., Murray, E., Neudert, J., Niblett, D., O'Leary, K., Pollard, H., Rankin, A., Rice, C. M., Sager, H., Sambrook, J., Schmitz, G., Scholz, M., Schroeder, L., Syvannen, A. C. & Wallace, C., 01.09.2011, In: PLoS Genetics. 7, 9, e1002260.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    27 Citations (Scopus)
  • 2010

    A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

    Heinig, M., Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S. R., Bauerfeind, A., Hummel, O., Lee, Y. A., Paskas, S., Rintisch, C., Saar, K., Cooper, J., Buchan, R., Gray, E. E., Cyster, J. G., Jeanette Erdmann, E., & 59 othersHengstenberg, C., Maouche, S., Ouwehand, W. H., Rice, C. M., Samani, N. J., Schunkert, H., Goodall, A. H., Schulz, H., Roider, H. G., Vingron, M., Blankenberg, S., Münzel, T., Zeller, T., Szymczak, S., Ziegler, A., Tiret, L., Smyth, D. J., Pravenec, M., Aitman, T. J., Cambien, F., Clayton, D., Todd, J. A., Hubner, N., Cook, S. A., Braund, P., Gracey, J., Krishnan, U., Moore, J. S., Nelson, C. P., Pollard, H., Attwood, T., Crisp-Hihn, A., Foad, N., Jolley, J., Lloyd-Jones, H., Muir, D., Murray, E., O'Leary, K., Rankin, A., Sambrook, J., Godfroy, T., Brocheton, J., Proust, C., Schmitz, G., Heimerl, S., Lugauer, I., Belz, S., Gulde, S., Linsel-Nitschke, P., Sager, H., Schroeder, L., Lundmark, P., Syvannen, A. C., Neudert, J., Scholz, M., Deloukas, P., Gray, E., Gwilliams, R. & Niblett, D., 23.09.2010, In: Nature. 467, 7314, p. 460-464 5 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    171 Citations (Scopus)
  • 2009

    Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in Acute Rejection of Human Renal Allografts

    Sager, H. B., Ergun, S., Hartmann, A., Hoffmann, U., Krämer, B. K., Mihatsch, M. J. & Weil, J., 06.2009, In: Transplantation Proceedings. 41, 5, p. 1536-1540 5 p.

    Research output: Journal ArticlesJournal articlesResearchpeer-review

    3 Citations (Scopus)