Hauke Stephan Busch

Prof. Dr. rer. nat.

Accepting PhD Students

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20002024

Research activity per year

Personal profile

Scientific Focus

Prof. Busch studied Theoretical Physics at the Technical University of Darmstadt, Germany, and Trinity College Dublin, Ireland. After finishing his PhD in 2004, dealing with numerical simulations on the interplay of noise and neuronal excitation, he started in the field of Systems Biology as a PostDoc at the Center for Modelling and Simulation in the Biosciences, University of Heidelberg, and German Cancer Research Center. His primary focus was on the development and simulation of protein signaling pathway models and gene regulatory networks. In 2009 he became a Junior research fellow at the Freiburg Institute of Advanced Studies (FRIAS) at the University of Freiburg.

Together with Dr. Dr. Melanie Börries he established a joint dry- and wet-lab at the Center for Biosystems Analysis (ZBSA), wherein they combined experimental research on cell-cell communication with the development of appropriate multi-scale dynamic models to investigate the necessary and sufficient control points that lead to cell proliferation, differentiation, migration or death.

In 2013, they moved their lab to the German Cancer Consortium partner site Freiburg at the Institute of Molecular Medicine and Cell Research, developing analysis pipelines for the stratification, diagnosis and therapy prediction of cancer patients based on sequencing technology.

Since October 2016, Prof. Busch is a newly appointed member of the Lübeck Institute of Experimental Dermatology and Member of the Excellence Cluster “Inflammation at Interfaces”, carrying over his Systems Biology approaches to study autoimmune diseases.

Further Academic Positions and Responsibilities:

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)
  • NUM: National Association of University Hospitals investigating SARS-CoV-2 / COVID-19 / Coronavirus
  • Research Area: Luebeck Integrated Oncology Network (LION)
  • Research Area: Medical Genetics

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Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • SFB 1665: Sexdiversity - Determinants, meanings and implications of sex diversity in sociocultural, medical and biological landscapes

    Hiort, O. (Speaker, Coordinator), Spielmann, M. (Principal Investigator (PI)), Holterhus, P. M. (Principal Investigator (PI)), Hornig, N. C. (Principal Investigator (PI)), Müller, F. J. (Principal Investigator (PI)), Frielitz-Wagner, I. (Principal Investigator (PI)), Mittag, J. (Principal Investigator (PI)), Kircher, M. (Principal Investigator (PI)), Seeger, K. (Principal Investigator (PI)), Kulle, A. E. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Aherrahrou, R. (Principal Investigator (PI)), Krämer, U. (Principal Investigator (PI)), Reisch, N. (Principal Investigator (PI)), Göpel, W. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Laudes, M. (Principal Investigator (PI)), Jürgensen, M. (Principal Investigator (PI)), Mangold, A. K. (Principal Investigator (PI)), Rehmann-Sutter, C. (Second Speaker/Coordinator), Stammberger, B. (Principal Investigator (PI)), Stoff, H. (Principal Investigator (PI)), Palm, K. (Principal Investigator (PI)), Malich, L. (Principal Investigator (PI)), Nemec, B. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)) & Kohlrausch, J. (Principal Investigator (PI))

    01.02.24 → …

    Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

  • Outlive-CRC - Liquid Biopsy and Nutrition in CRC Prevention

    Derer-Petersen, S. (Speaker, Coordinator), Burziwoda, D. (Principal Investigator (PI)), Katalinic, A. (Principal Investigator (PI)), Oberländer, M. (Principal Investigator (PI)), Deck, R. (Principal Investigator (PI)), Sültmann, H. (Principal Investigator (PI)), von Bubnoff, N. (Principal Investigator (PI)), Gemoll, T. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Jülg, P. (Principal Investigator (PI)), Hutzenlaub, T. (Principal Investigator (PI)), Sina, C. (Principal Investigator (PI)), Schröder, T. (Principal Investigator (PI)) & Lill, C. (Project Staff)

    01.03.2231.12.25

    Project: Projects with Federal FundingFederal Funding: BMBF (Education and Research)

  • CRC 1526, INF: Information Infrastructure Project

    Busch, H. S. (Principal Investigator (PI)) & Höppner, M. (Principal Investigator (PI))

    01.01.22 → …

    Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

  • CRC 1526, PANTAU: Pathomechanisms of Antibody-mediated Autoimmunity

    Sadik, C. (Speaker, Coordinator), Zillikens, D. (Speaker, Coordinator), Scheffold, A. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)), Heine, G. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)), Peipp, M. (Principal Investigator (PI)), Hammers, M. C. (Principal Investigator (PI)), Verschoor, A. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), Nimmerjahn, F. (Principal Investigator (PI)), Hutloff, A. (Principal Investigator (PI)), Ibrahim, S. (Principal Investigator (PI)), Wettschureck, N. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)), Schilf, P. (Principal Investigator (PI)), Vaeth, M. (Principal Investigator (PI)), Hirose, M. (Principal Investigator (PI)), Vaeth, M. (Principal Investigator (PI)), Baines, J. F. (Principal Investigator (PI)), Bacher, P. (Principal Investigator (PI)), Hoffmann, M. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Höppner, M. (Principal Investigator (PI)), Becker, M. (Principal Investigator (PI)), Holtsche, M. M. (Principal Investigator (PI)), Fähnrich, A. (Principal Investigator (PI)), Szymczak, S. (Principal Investigator (PI)), Murthy, S. (Principal Investigator (PI)) & Lux, A. (Principal Investigator (PI))

    01.01.22 → …

    Project: DFG ProjectsDFG Joint Research: Collaborative Research Center/ Transregios

  • Identification of pathogenic structural variants and repeat expansions in Parkinson's disease

    Busch, H. S. (Principal Investigator (PI)), Lohmann, K. (Principal Investigator (PI)) & Trinh, J. (Principal Investigator (PI))

    01.01.2131.12.25

    Project: DFG ProjectsDFG Individual Projects