Harald Langer

2023

Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor-modulating factors

Nording, H., Baron, L., Sauter, M., Lübken, A., Rawish, E., Szepanowski, R., Esebeck, J. V., Sun, Y., Emami, H., Meusel, M., Saraei, R., Schanze, N., Gorantla, S. P., Bubnoff, N. V., Geisler, T., Hundelshausen, P. V., Stellos, K., Marquardt, J., Sadik, C. D., Köhl, J., & 3 othersDuerschmied, D., Kleinschnitz, C. & Langer, H. F., 14.11.2023, In: Blood Advances. 7, 21, p. 6411-6427 17 p.

Research output: Journal Articles › Journal articles › Research › peer-review

2021

Deep sedation versus general anaesthesia for transcatheter mitral valve repair: An individual patient data meta-analysis of observational studies

Jobs, A., Grund, S., De Waha-Thiele, S., Ledwoch, J., Sievert, H., Rassaf, T., Luedike, P., Kelm, M., Hellhammer, K., Horn, P., Westenfeld, R., Patzelt, J., Langer, H. F., Lurz, P., Desch, S., Eitel, I. & Thiele, H., 2021, In: EuroIntervention. 16, 16, p. 1359-1365 7 p.

Research output: Journal Articles › Journal articles › Research › peer-review

6 Citations (Scopus)

Impact of Ventricular Stroke Work Indices on Mortality in Heart Failure Patients After Percutaneous Mitral Valve Repair

Osteresch, R., Diehl, K., Dierks, P., Schmucker, J., Ammar, A. B., Fach, A., Langer, H., Eitel, I., Hambrecht, R. & Wienbergen, H., 15.05.2021, In: American Journal of Cardiology. 147, p. 101-108 8 p.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets

Nording, H., Baron, L., Haberthür, D., Emschermann, F., Mezger, M., Sauter, M., Sauter, R., Patzelt, J., Knoepp, K., Nording, A., Meusel, M., Meyer-Saraei, R., Hlushchuk, R., Sedding, D., Borst, O., Eitel, I., Karsten, C. M., Feil, R., Pichler, B., Erdmann, J., & 7 othersVerschoor, A., Chavakis, E., Chavakis, T., von Hundelshausen, P., Köhl, J., Gawaz, M. & Langer, H. F., 12.2021, In: Nature Communications. 12, 1, p. 3352 3352.

Research output: Journal Articles › Journal articles › Research › peer-review

2020

CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect

Reil, J. C., Reil, G. H., Kovács, Á., Sequeira, V., Waddingham, M. T., Lodi, M., Herwig, M., Ghaderi, S., Kreusser, M. M., Papp, Z., Voigt, N., Dobrev, D., Meyhöfer, S., Langer, H. F., Maier, L. S., Linz, D., Mügge, A., Hohl, M., Steendijk, P. & Hamdani, N., 01.08.2020, In: Journal of Physiology. 598, 15, p. 3129-3153 25 p.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

Impact of morphine treatment on infarct size and reperfusion injury in acute reperfused st-elevation myocardial infarction

Eitel, I., Wang, J., Stiermaier, T., Fuernau, G., Feistritzer, H. J., Joost, A., Jobs, A., Meusel, M., Blodau, C., Desch, S., de Waha-Thiele, S., Langer, H. & Thiele, H., 03.2020, In: Journal of Clinical Medicine. 9, 3, 735.

Research output: Journal Articles › Journal articles › Research › peer-review

11 Citations (Scopus)

Impact of Morphine Treatment with and without Metoclopramide Coadministration on Ticagrelor-Induced Platelet Inhibition in Acute Myocardial Infarction: The Randomized MonAMI Trial

Saad, M., Meyer-Saraei, R., De Waha-Thiele, S., Stiermaier, T., Graf, T., Fuernau, G., Langer, H. F., Kurz, T., Pöss, J., Barkausen, J., Desch, S., Eitel, I. & Thiele, H., 21.04.2020, In: Circulation. 141, 16, p. 1354-1356 3 p.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

New technologies for intensive prevention programs after myocardial infarction: rationale and design of the NET-IPP trial

Wienbergen, H., Fach, A., Erdmann, J., Katalinic, A., Eisemann, N., Krawitz, P., Maj, C., Borisov, O., Munz, M., Noethen, M., Meyer-Saraei, R., Osteresch, R., Schmucker, J., Linke, A., Eitel, I., Hambrecht, R. & Langer, H., 2020, In: Clinical Research in Cardiology.

Research output: Journal Articles › Journal articles › Research › peer-review

Platelets as Mediators of Neuroinflammation and Thrombosis

Rawish, E., Nording, H., Münte, T. & Langer, H. F., 06.10.2020, In: Frontiers in Immunology. 11, p. 548631 548631.

Research output: Journal Articles › Scientific review articles › Research

The Use of Extracorporeal Life Support in a Patient Suffering from Venlafaxine Intoxication. A Case Report

Marquetand, C., Langer, H. F., Klein, J. P. & Graf, T., 01.04.2020, In: Journal of Critical Care Medicine. 6, 2, p. 120-123 4 p.

Research output: Journal Articles › Journal articles › Research › peer-review

5 Citations (Scopus)

2019

Anaphylatoxin Receptor C3aR Contributes to Platelet Function, Thrombus Formation and in Vivo Haemostasis

Sauter, R. J., Sauter, M., Obrich, M., Emschermann, F. N., Nording, H., Patzelt, J., Wendel, H. P., Reil, J. C., Edlich, F. & Langer, H. F., 31.12.2019, In: Thrombosis and Haemostasis. 119, 1, p. 179-182 4 p.

Research output: Journal Articles › Letters › peer-review

4 Citations (Scopus)

Conventional echocardiographic parameters or three-dimensional echocardiography to evaluate right ventricular function in percutaneous edge-to-edge mitral valve repair (PMVR)

Sauter, R. J., Patzelt, J., Mezger, M., Nording, H., Reil, J. C., Saad, M., Seizer, P., Schreieck, J., Rosenberger, P., Langer, H. F. & Magunia, H., 09.2019, In: IJC Heart and Vasculature. 24, 100413.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

ECG changes after percutaneous edge-to-edge mitral valve repair

Bo, H., Heinzmann, D., Grasshoff, C., Rosenberger, P., Schlensak, C., Gawaz, M., Schreieck, J., Langer, H. F., Patzelt, J. & Seizer, P., 01.11.2019, In: Clinical Cardiology. 42, 11, p. 1094-1099 6 p.

Research output: Journal Articles › Journal articles › Research › peer-review

EKG-Zeichen eines akuten Koronarsyndroms

Translated title of the contribution: ECG signs of acute coronary syndromeBrüggemann, B., Eitel, C., Graf, T., Grimm, K., Grimm, W., Heeger, C., Israel, C. W., Krauspe, J., Kalantaryan, V., Langer, H., Luck, K., Mischke, K., Parahuleva, M., Tilz, R. R., Touati, S., Tribunyan, S. & Vogler, J., 01.03.2019, In: Herzschrittmachertherapie und Elektrophysiologie. 30, 1, p. 89-101 13 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Elevated mitral valve pressure gradient is predictive of long-term outcome after percutaneous edge-to-edge mitral valve repair in patients with degenerative mitral regurgitation (MR), but not in functional MR

Patzelt, J., Zhang, W., Sauter, R., Mezger, M., Nording, H., Ulrich, M., Becker, A., Patzelt, T., Rudolph, V., Eitel, I., Saad, M., Bamberg, F., Schlensak, C., Gawaz, M., Boekstegers, P., Schreieck, J., Seizer, P. & Langer, H. F., 01.07.2019, In: Journal of the American Heart Association. 8, 13, p. e011366 e011366.

Research output: Journal Articles › Journal articles › Research › peer-review

Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis

Michels da Silva, D., Langer, H. & Graf, T., 01.05.2019, In: International Journal of Molecular Sciences. 20, 9, 2322.

Research output: Journal Articles › Scientific review articles › Research

Long-term risk factor control after myocardial infarction—A need for better prevention programmes

Osteresch, R., Fach, A., Schmucker, J., Eitel, I., Langer, H., Hambrecht, R. & Wienbergen, H., 08.2019, In: Journal of Clinical Medicine. 8, 8, 1114.

Research output: Journal Articles › Scientific review articles › Research

6 Citations (Scopus)

Platelets and Immune Responses During Thromboinflammation

Mezger, M., Nording, H., Sauter, R., Graf, T., Heim, C., von Bubnoff, N., Ensminger, S. M. & Langer, H. F., 26.07.2019, In: Frontiers in Immunology. 10, p. 1731 1 p.

Research output: Journal Articles › Scientific review articles › Research

9 Citations (Scopus)

Treatment of a patient with primary mitral regurgitation using the Cardioband® system

Götz, N., Schreieck, J., Langer, H. F. & Patzelt, J., 14.05.2019, In: European Heart Journal - Case Reports. 3, 2

Research output: Journal Articles › Comments/Debates

Treatment of Recurrent MR by MitraClip XTR in a Patient With a PASCAL Device

Marquetand, C., Reil, J. C., Saad, M., Langer, H. F. & Patzelt, J., 23.12.2019, In: JACC: Cardiovascular Interventions. 12, 24, p. e219-e221

Research output: Journal Articles › Journal articles › Research › peer-review

2018

A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis

Wen, L., Feil, S., Wolters, M., Thunemann, M., Regler, F., Schmidt, K., Friebe, A., Olbrich, M., Langer, H., Gawaz, M., de Wit, C. & Feil, R., 16.10.2018, In: Nature Communications. 9, 1, p. 4301

Research output: Journal Articles › Journal articles › Research › peer-review

Previous TAVR in patients undergoing percutaneous edge-to-edge mitral valve repair (PMVR) affects improvement of MR

Patzelt, J., Ulrich, M., Becker, A., Müller, K. A. L., Jorbenadze, R., Droppa, M., Zhang, W., Mandel, S., Habel, L., Lausberg, H., Pöss, J., Geisler, T., Borst, O., Rosenberger, P., Schlensak, C., Gawaz, M., Schreieck, J., Seizer, P. & Langer, H. F., 10.2018, In: PLoS ONE. 13, 10, e0205930.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

Publisher Correction: A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis

Wen, L., Feil, S., Wolters, M., Thunemann, M., Regler, F., Schmidt, K., Friebe, A., Olbrich, M., Langer, H., Gawaz, M., de Wit, C. & Feil, R., 20.11.2018, In: Nature Communications. 9, 1, p. 4969

Research output: Journal Articles › Journal articles › Research › peer-review