• 35013
    Citations
1995 …2024

Research activity per year

Personal profile

Scientific Focus

Translational Neurogenetics

The Translational Neurogenetics Section comprises six research groups, each headed by a junior group leader, who are working towards the common goal of transferring basic research findings from the laboratory into clinical practice. To this end, a main focus is on the development of biomarkers and readout parameters that will not only improve our understanding of the pathophysiology of inherited movement disorders but that may also serve as the basis for testing rescue strategies and for the development of new drug targets in human cellular models (induced pluripotent stem cell-derived neurons) as well as in animal models (drosophila and mice).
Through its intimate connection to the patient facilities and Lübeck Center for Rare Diseases, potential treatment options can be tested in clinical practice. For example, the Section has recently been funded by the Federal Ministry of Education and Research (BMBF) to carry out a clinical trial in Parkinson disease patients genetically predisposed to mitochondrial dysfunction using mitochondrial enhancer strategies (Coenzyme Q10 and Vitamin K2).

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Areas and Centers

  • Research Area: Medical Genetics
  • Research Area: Center for Population Medicine and Public Health (ZBV)
  • NUM: National Association of University Hospitals investigating SARS-CoV-2 / COVID-19 / Coronavirus
  • Centers: Center for Rare Diseases (ZSE)

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Collaborations and top research areas from the last five years

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