Institute of Experimental Dermatology

Projects

Projects per year 2010 2022 2026

• 7 Finished
• 19 Active

Projects per year

Search results

• Active

  SFB 1665: Sexdiversity - Determinants, meanings and implications of sex diversity in sociocultural, medical and biological landscapes

  Hiort, O. (Speaker, Coordinator), Spielmann, M. (Principal Investigator (PI)), Holterhus, P. M. (Principal Investigator (PI)), Hornig, N. C. (Principal Investigator (PI)), Müller, F. J. (Principal Investigator (PI)), Frielitz-Wagner, I. (Principal Investigator (PI)), Mittag, J. (Principal Investigator (PI)), Kircher, M. (Principal Investigator (PI)), Seeger, K. (Principal Investigator (PI)), Kulle, A. E. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Aherrahrou, R. (Principal Investigator (PI)), Krämer, U. (Principal Investigator (PI)), Reisch, N. (Principal Investigator (PI)), Göpel, W. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Laudes, M. (Principal Investigator (PI)), Jürgensen, M. (Principal Investigator (PI)), Mangold, A. K. (Principal Investigator (PI)), Rehmann-Sutter, C. (Second Speaker/Coordinator), Stammberger, B. (Principal Investigator (PI)), Stoff, H. (Principal Investigator (PI)), Palm, K. (Principal Investigator (PI)), Malich, L. (Principal Investigator (PI)), Nemec, B. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)) & Kohlrausch, J. (Principal Investigator (PI))

  01.02.24 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Disorders of Sex Development 100%
  • Androgen Receptor 36%
  • Gender and Sex 28%
  • Adolescence 28%

• Outlive-CRC - Liquid Biopsy and Nutrition in CRC Prevention

  Derer-Petersen, S. (Speaker, Coordinator), Burziwoda, D. (Principal Investigator (PI)), Katalinic, A. (Principal Investigator (PI)), Oberländer, M. (Principal Investigator (PI)), Deck, R. (Principal Investigator (PI)), Sültmann, H. (Principal Investigator (PI)), von Bubnoff, N. (Principal Investigator (PI)), Gemoll, T. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Jülg, P. (Principal Investigator (PI)), Hutzenlaub, T. (Principal Investigator (PI)), Sina, C. (Principal Investigator (PI)), Schröder, T. (Principal Investigator (PI)) & Lill, C. (Project Staff)

  01.03.22 → 31.12.25

  Project: Projects with Federal Funding › Federal Funding: BMBF (Education and Research)

  • Colorectal Carcinoma 100%
  • Liquid Biopsy 100%
  • Tertiary Prevention 66%
  • Social Participation 66%
  • Tumor Cell 33%

• CRC 1526, Project A08: Skin-infiltrating T and B cells in the pathogenesis of pemphigoid diseases

  Ibrahim, S. (Principal Investigator (PI)) & Hutloff, A. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • B Cell 100%
  • Pemphigoid 100%
  • T Cell 100%
  • Inflammatory Cell 33%
  • Single-Cell Sequencing 33%

• CRC 1526, Service Projects

  Becker, M. (Principal Investigator (PI)), Heine, G. (Principal Investigator (PI)), Holtsche, M. M. (Principal Investigator (PI)), Fähnrich, A. (Principal Investigator (PI)), Szymczak, S. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)) & Murthy, S. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Pemphigoid 100%

• Identification of novel therapeutic targets for the treatment of autoantibody-induced tissue pathology in pemphigus

  Hundt, J. (Principal Investigator (PI)) & Ludwig, R. (Principal Investigator (PI))

  01.01.22 → 31.12.26

  Project: DFG Projects › DFG Individual Projects

  • Autoantibody 100%
  • Pemphigus 100%
  • Rituximab 50%
  • Keratinocyte 50%
  • Phosphotransferase 50%

• CRC 1526, Project B01: Site-specific inhibition of C5/C5a in pemphigoid diseases

  Ludwig, R. (Principal Investigator (PI)) & Peipp, M. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Complement Component 5a 100%
  • Pemphigoid 100%
  • Therapeutic Antibodies 25%
  • Bispecific Antibody 25%
  • Mouse Model 25%

• CRC 1526, INF: Information Infrastructure Project

  Busch, H. S. (Principal Investigator (PI)) & Höppner, M. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• CRC 1526, Project A01: Autoantigen-specific T cells in pemphigoid diseases

  Scheffold, A. (Principal Investigator (PI)) & Schmidt, E. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Pemphigoid 100%
  • T Cell 100%
  • Autoantigen 100%

• CRC 1526, Project A04: Selective B cell depletion in pemphigoid diseases by bispecific antibodies

  Ludwig, R. (Principal Investigator (PI)) & Peipp, M. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • B Cell 100%
  • Bispecific Antibody 100%
  • Pemphigoid 100%
  • Cell Population 33%

• CRC 1526, Project B06: Targeting mitochondrial metabolism in pemphigoid diseases

  Hirose, M. (Principal Investigator (PI)) & Vaeth, M. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Mitochondrial Respiration 100%
  • Pemphigoid 100%
  • Autoimmunity 50%
  • Lymphocyte 25%
  • Mitochondrial Genome 25%

• CRC 1526, Project B07: Characterization and targeted modulation of the gut - skin axis in pemphigoid diseases

  Ibrahim, S. (Principal Investigator (PI)) & Baines, J. F. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Gut 100%
  • Pemphigoid 100%
  • Gut Microbiota 40%
  • Intestine Flora 40%

• CRC 1526, Project B04: Kinase cascades in neutrophils as therapeutic target in pemphigoid diseases

  Bieber, K. (Principal Investigator (PI)) & Lux, A. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Neutrophil 100%
  • Pemphigoid 100%
  • Phosphotransferase 100%
  • Intracellular Signaling 33%
  • Autoantibody 33%

• CRC 1526, PANTAU: Pathomechanisms of Antibody-mediated Autoimmunity

  Sadik, C. (Speaker, Coordinator), Zillikens, D. (Speaker, Coordinator), Scheffold, A. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)), Heine, G. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)), Peipp, M. (Principal Investigator (PI)), Hammers, M. C. (Principal Investigator (PI)), Verschoor, A. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), Nimmerjahn, F. (Principal Investigator (PI)), Hutloff, A. (Principal Investigator (PI)), Ibrahim, S. (Principal Investigator (PI)), Wettschureck, N. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)), Schilf, P. (Principal Investigator (PI)), Vaeth, M. (Principal Investigator (PI)), Hirose, M. (Principal Investigator (PI)), Vaeth, M. (Principal Investigator (PI)), Baines, J. F. (Principal Investigator (PI)), Bacher, P. (Principal Investigator (PI)), Hoffmann, M. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Höppner, M. (Principal Investigator (PI)), Becker, M. (Principal Investigator (PI)), Holtsche, M. M. (Principal Investigator (PI)), Fähnrich, A. (Principal Investigator (PI)), Szymczak, S. (Principal Investigator (PI)), Murthy, S. (Principal Investigator (PI)) & Lux, A. (Principal Investigator (PI))

  01.01.22 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Autoantibody 100%
  • Bullous Pemphigoid 98%
  • Pemphigoid 76%
  • Cicatricial Pemphigoid 54%
  • Neutrophil 53%

• Identification and characterization of the keratinocyte kinome and secretome in pemphigoid disease

  Kamaguchi, M. (Principal Investigator (PI))

  01.01.21 → 31.12.25

  Project: DFG Projects › DFG Individual Projects

  • Kinome 100%
  • Pemphigoid 100%
  • Keratinocyte 100%
  • Secretome 100%
  • Autoantibody 58%

• Identification of pathogenic structural variants and repeat expansions in Parkinson's disease

  Busch, H. S. (Principal Investigator (PI)), Lohmann, K. (Principal Investigator (PI)) & Trinh, J. (Principal Investigator (PI))

  01.01.21 → 31.12.25

  Project: DFG Projects › DFG Individual Projects

  • Genome Sequencing 100%
  • Single-Nucleotide Polymorphism 66%
  • Exome Sequencing 33%
  • Copy-Number Variation 33%
  • Polygenic Score 33%

• DFG Research Training Group RTG 2633: Defining and Targeting Autoimmune Pre-Disease

  Ludwig, R. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Ehlers, M. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)), Kalies, K. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Lamprecht, P. (Principal Investigator (PI)), Lange, T. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Petersen, F. (Principal Investigator (PI)), Raasch, W. (Principal Investigator (PI)), Riemekasten, G. (Principal Investigator (PI)), Sadik, C. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)) & Yu, X. (Principal Investigator (PI))

  01.01.21 → …

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Autoimmunity 100%
  • Autoimmune Disease 66%
  • Biological Marker 33%

• Elucidating novel genetic causes of dystonia by large-scale sequencing

  Busch, H. S. (Principal Investigator (PI)), Klein, C. (Principal Investigator (PI)), Lohmann, K. (Principal Investigator (PI)) & Bäumer, T. (Associated Staff)

  01.01.20 → …

  Project: DFG Projects › DFG Individual Projects

  • Genome Sequencing 100%
  • SNP Genotyping 100%
  • Genetic Risk 100%
  • Induced Pluripotent Stem Cell 100%
  • RNA Sequencing 100%

• RU 2488 Project: Maintenance and Extension of a Central Project Knowledge Base (CPKB), systems biomedicine and statistics pipeline

  Busch, H. S. (Principal Investigator (PI)), Krawczak, M. (Principal Investigator (PI)), Erdmann, J. (Principal Investigator (PI)) & König, I. R. (Principal Investigator (PI))

  01.01.16 → …

  Project: DFG Projects › DFG Individual Projects

  • Base 100%
  • Knowledge Base 100%
  • Parkinson's Disease 66%
  • Metabolome 33%
  • Phenome 33%

• RU 2488, Project: Modifiers of penetrance and expressivity in monogenic dystonia: Insights from systems biology

  Lohmann, K. (Principal Investigator (PI)) & Busch, H. S. (Principal Investigator (PI))

  01.01.16 → …

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Synapsin I 100%
  • Penetrance 100%
  • Programmed Cell Death 100%
  • Sarcoglycan 41%
  • GTP Cyclohydrolase I 41%
• Finished

  DFG Scholarship for Returning Scientists

  Stefan, K. (Principal Investigator (PI)) & Busch, H. S. (Project Staff)

  01.01.23 → 31.12.24

  Project: DFG Projects › DFG Scholarships: Walter Benjamin Programme

• Establishment of new detection methods for the discovery and development of novel ABCA1 and ABCA7 modulators as Alzheimer’s disease (AD) therapeutics and diagnostics

  Stefan, K. (Principal Investigator (PI)) & Pahnke, J. (Principal Investigator (PI))

  01.01.21 → 31.12.23

  Project: DFG Projects › DFG Scholarships: Walter Benjamin Programme

  • ABCA1 100%
  • ABCA7 100%
  • Alzheimer's Disease 100%

• Design, synthesis, and biological assessment of ABC transporter agonists for the development of novel Alzheimer’s disease therapeutics

  Stefan, S. M. (Principal Investigator (PI)) & Pahnke, J. (Project Staff)

  01.01.20 → 31.12.23

  Project: DFG Projects › DFG Scholarships: Walter Benjamin Programme

  • Agonist 100%
  • ABCG2 100%
  • ABC Transporter 100%
  • ATP-binding Cassette Transporter 100%
  • Alzheimer's Disease 100%

• CRU 303: Pemphigoid Diseases - Molecular Pathways and their Therapeutic Potential

  Sadik, C. (Speaker, Coordinator), Zillikens, D. (Speaker, Coordinator), Ibrahim, S. (Principal Investigator (PI)), Baines, J. F. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Ehlers, M. (Principal Investigator (PI)), Hirose, M. (Principal Investigator (PI)), König, P. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Schwaninger, M. (Principal Investigator (PI)), Beek, N. (Principal Investigator (PI)), Erdmann, J. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Verschoor, A. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)) & Busch, H. S. (Principal Investigator (PI))

  01.04.15 → 31.12.23

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Bullous Pemphigoid 100%
  • Pemphigoid 97%
  • Autoantibody 42%
  • Comorbidity 40%
  • Bullous Disease 26%

• DFG RTG 1727: Modulation of Autoimmunity

  Zillikens, D. (Speaker, Coordinator), Ehlers, M. (Project Staff), Hölscher, C. (Project Staff), Kalies, K. (Project Staff), Köhl, J. (Project Staff), Lamprecht, P. (Project Staff), Laskay, T. (Project Staff), Ludwig, R. (Project Staff), Manz, R. (Project Staff), Müller, A. (Project Staff), Petersen, F. (Project Staff), Schmidt, E. (Project Staff), Seeger, K. (Project Staff), Westermann, J. (Project Staff) & Yu, X. (Project Staff)

  01.04.11 → 31.12.20

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Germinal Center 100%
  • Dermatitis 62%
  • T Cell 57%
  • Follicular B Helper T Cells 55%
  • Neutrophil 50%

• Efficacy and safety of adjuvant immunoadsorption in pemphigus

  Schmidt, E. (Principal Investigator (PI)) & Eming, R. (Principal Investigator (PI))

  01.01.10 → 01.01.18

  Project: DFG Projects › DFG Clinical Trials

  • Pemphigus 100%
  • Autoantibody 100%
  • Immunoadsorption 100%
  • Remission 80%
  • Prednisolone 60%

• CRC 850, Project Z01: Systems biology, pathology and proteomics

  Busch, H. S. (Principal Investigator (PI)), Börries, M. (Principal Investigator (PI)), Lassmann, S. (Principal Investigator (PI)) & Schilling, O. (Principal Investigator (PI))

  01.01.10 → 31.12.21

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Interaction Proteomics 100%
  • Quantitative Proteomics 100%