Research Output per year
Research Output per year
Organisation profile
About us
Autoimmune and chronic inflammatory skin diseases, such as pemphigoid, pemphigus, lupus erythematosus and psoriasis pose a major medical burden. Our mission at LIED is to identify the genetic and molecular basis of these diseases, enabling better diagnosis and treatment for patients.
LIED research is divided into four groups:
1. Medical Systems Biology (→Prof. Busch)
2. Visualisation of Cutaneous Inflammation (→Prof. Hundt)
3. Model Systems of Inflammatory Skin Diseases (→Prof. Ludwig)
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Research output
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Exploring the effect of sequential antibiotic exposure in resistant Escherichia coli causing urinary tract infections: a proof of principle study.
Göpel, L., Kirchhoff, L., Gopleac, O., Tüeffers, L., Hauswaldt, S., Boutin, S., Rupp, J. & Nurjadi, D., 04.03.2025, In: Microbiology spectrum. 13, 3, p. e0252524 e02525-24.Research output: Journal Articles › Journal articles › Research › peer-review
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Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Specific Target Antigen Expression
Rastegar Lari, T., Macias, L., Robrahn, L., Dikmen, H. O., Prüßmann, J., Kiehne, C., Engster, S., Weyers, I., Szymczak, S., van Beek, N., Hoffmann, M. H., Schmidt, E. & Emtenani, S., 02.2025, In: Life. 15, 2, 218.Research output: Journal Articles › Journal articles › Research › peer-review
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Anti-Laminin β4 IgG Drives Tissue Damage in Anti-p200 Pemphigoid and Shows Interactions with Laminin α3 and γ1/2 Chains
Pigors, M., Goletz, S., Wang, Y., Emtenani, S., Hammers, C. M., Holtsche, M. M., Patzelt, S., Opelka, B., Stang, F. H., König, I. R., Radzimski, C., Komorowski, L., Aumailley, M., Has, C. & Schmidt, E., 2024, In: The Journal of investigative dermatology.Research output: Journal Articles › Journal articles › Research › peer-review
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SFB 1665: Sexdiversity - Determinants, meanings and implications of sex diversity in sociocultural, medical and biological landscapes
Hiort, O. (Speaker, Coordinator), Spielmann, M. (Principal Investigator (PI)), Holterhus, P. M. (Principal Investigator (PI)), Hornig, N. C. (Principal Investigator (PI)), Müller, F. J. (Principal Investigator (PI)), Frielitz-Wagner, I. (Principal Investigator (PI)), Mittag, J. (Principal Investigator (PI)), Kircher, M. (Principal Investigator (PI)), Seeger, K. (Principal Investigator (PI)), Kulle, A. E. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Aherrahrou, R. (Principal Investigator (PI)), Krämer, U. (Principal Investigator (PI)), Reisch, N. (Principal Investigator (PI)), Göpel, W. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Laudes, M. (Principal Investigator (PI)), Jürgensen, M. (Principal Investigator (PI)), Mangold, A. K. (Principal Investigator (PI)), Rehmann-Sutter, C. (Second Speaker/Coordinator), Stammberger, B. (Principal Investigator (PI)), Stoff, H. (Principal Investigator (PI)), Palm, K. (Principal Investigator (PI)), Malich, L. (Principal Investigator (PI)), Nemec, B. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)) & Kohlrausch, J. (Principal Investigator (PI))
01.02.24 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
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Outlive-CRC - Liquid Biopsy and Nutrition in CRC Prevention
Derer-Petersen, S. (Speaker, Coordinator), Burziwoda, D. (Principal Investigator (PI)), Katalinic, A. (Principal Investigator (PI)), Oberländer, M. (Principal Investigator (PI)), Deck, R. (Principal Investigator (PI)), Sültmann, H. (Principal Investigator (PI)), von Bubnoff, N. (Principal Investigator (PI)), Gemoll, T. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Jülg, P. (Principal Investigator (PI)), Hutzenlaub, T. (Principal Investigator (PI)), Sina, C. (Principal Investigator (PI)), Schröder, T. (Principal Investigator (PI)) & Lill, C. (Project Staff)
01.03.22 → 31.12.25
Project: Projects with Federal Funding › Federal Funding: BMBF (Education and Research)
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CRC 1526, Project A08: Skin-infiltrating T and B cells in the pathogenesis of pemphigoid diseases
Ibrahim, S. (Principal Investigator (PI)) & Hutloff, A. (Principal Investigator (PI))
01.01.22 → …
Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios
Prizes
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Friedrich-Wingert-Preis 2020
Riech, K. P. (Award Recipient) & Reimer, N. (Award Recipient), 17.06.2020
Prize: Research Prizes, Scientific Awards
Datasets
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Image-derived models of cell organization changes during differentiation and drug treatments
Ruan, X. (Scientific Creator), Johnson, G. R. (Scientific Creator), Bierschenk, I. (Scientific Creator), Nitschke, R. (Scientific Creator), Boerries, M. (Scientific Creator), Busch, H. (Scientific Creator) & Murphy, R. F. (Scientific Creator), Dryad, 13.01.2020
DOI: 10.5061/dryad.hc8037v, https://datadryad.org/stash/dataset/doi:10.5061/dryad.hc8037v
Dataset
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Data from: Population genomics of natural and experimental populations of guppies (Poecilia reticulata)
Fraser, B. A. (Contributor), Künstner, A. (Contributor), Reznick, D. N. (Contributor), Dreyer, C. (Contributor) & Weigel, D. (Contributor), ZENODO, 26.11.2014
DOI: 10.5061/dryad.n35j4, https://zenodo.org/records/4953988
Dataset
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Smoking Modifies the Genetic Risk for Early-Onset Periodontitis
Freitag-Wolf, S. (Contributor), Munz, M. (Contributor), Wiehe, R. (Contributor), Junge, O. (Contributor), Graetz, C. (Contributor), Jockel-Schneider, Y. (Contributor), Staufenbiel, I. (Contributor), Bruckmann, C. (Contributor), Lieb, W. (Contributor), Franke, A. (Contributor), Loos, B. G. (Contributor), Jepsen, S. (Contributor), Dommisch, H. (Contributor) & Schaefer, A. S. (Contributor), SAGE Journals, 2019
DOI: 10.25384/sage.c.4674239, https://sage.figshare.com/collections/Smoking_Modifies_the_Genetic_Risk_for_Early-Onset_Periodontitis/4674239
Dataset