Institute of Experimental and Clinical Pharmacology and Toxicology

Projects

Projects per year 1999 2005 2014 2026

• 11 Active
• 25 Finished

Projects per year

Search results

• Active

  MSCA Postdoctoral Fellowship

  Rivagorda, M. (Principal Investigator (PI))

  01.05.24 → 30.04.26

  Project: EU Funding › MSCA Funding

  • Experimental Pharmacology 100%

• DFG Major Research Instrumentation: Confocal Laser Scanning Microscope

  Schwaninger, M. (Principal Investigator (PI))

  01.01.23 → …

  Project: DFG Projects › DFG Major Research Instrumentation

  • Confocal Microscope 100%
  • Confocal Laser Scanning Microscope 100%
  • Scanning Electron Microscope 100%
  • Confocal Microscopy 100%
  • Sensitive Detection 50%

• DFG Research Training Group RTG 2633: Defining and Targeting Autoimmune Pre-Disease

  Ludwig, R. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)), Busch, H. S. (Principal Investigator (PI)), Ehlers, M. (Principal Investigator (PI)), Hundt, J. (Principal Investigator (PI)), Kalies, K. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Lamprecht, P. (Principal Investigator (PI)), Lange, T. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Petersen, F. (Principal Investigator (PI)), Raasch, W. (Principal Investigator (PI)), Riemekasten, G. (Principal Investigator (PI)), Sadik, C. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)) & Yu, X. (Principal Investigator (PI))

  01.01.21 → …

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Autoimmune Disease 100%
  • Biological Marker 50%
  • Autoimmunity 50%
  • Translational Research 25%
  • Disease Exacerbation 25%

• Modulation of neuroinflammation by novel endothelial GPCRs

  Schwaninger, M. (Principal Investigator (PI)) & Wettschureck, N. (Principal Investigator (PI))

  01.01.21 → 31.12.25

  Project: DFG Projects › DFG Individual Projects

  • Leukocyte 100%
  • Blood Brain Barrier 100%
  • Knockout Mouse 100%
  • Humoral Antibody 100%
  • Mediator 100%

• CRC/Transregio TRR 296 LocoTact, Project P01: TH transporters at brain barriers

  Heuer, H. (Principal Investigator (PI)) & Schwaninger, M. (Principal Investigator (PI))

  01.01.20 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• CRC/Transregio TRR 296 LocoTact, Project P02: Impact of TH on tanycyte functions and the relevance on central regulation of the liver and hormone uptake

  Müller-Fielitz, H. (Principal Investigator (PI))

  01.01.20 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Tanycyte 100%
  • Hormone Transport 100%
  • Liver Metabolism 25%
  • Cerebrospinal Fluid 25%

• CRC/Transregio TRR 296 LocoTact: Local control of TH action

  Führer-Sakel, D. (Speaker, Coordinator), Mittag, J. (Second Speaker/Coordinator), Kühnen, P. (Second Speaker/Coordinator), Heuer, H. (Principal Investigator (PI)), Schwaninger, M. (Principal Investigator (PI)), Müller-Fielitz, H. (Principal Investigator (PI)), Bechmann, I. (Principal Investigator (PI)), Biebermann, H. (Principal Investigator (PI)), Müller, T. (Principal Investigator (PI)), Pfluger, P. (Principal Investigator (PI)), Krude, H. (Principal Investigator (PI)), Schülke-Gerstenfeld, M. (Principal Investigator (PI)), Cirkel, A. (Principal Investigator (PI)), Münte, T. (Principal Investigator (PI)), Kleinschnitz, C. (Principal Investigator (PI)), Langhauser, F. (Principal Investigator (PI)), Engel, D. R. (Principal Investigator (PI)), Möller, L. (Principal Investigator (PI)), Kaiser, F. (Principal Investigator (PI)), Oster, H. (Principal Investigator (PI)), Kirchner, H. (Principal Investigator (PI)), Spranger, J. (Principal Investigator (PI)), Tacke, F. (Principal Investigator (PI)), Wirth, E. K. (Principal Investigator (PI)), Köhrle, J. (Principal Investigator (PI)), Schomburg, L. (Principal Investigator (PI)), Lange, C. M. (Principal Investigator (PI)), Zwanziger, D. (Principal Investigator (PI)), Mayerl, S. (Principal Investigator (PI)) & Stachelscheid, H. (Principal Investigator (PI))

  01.01.20 → …

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Thyroid Hormone 100%
  • Regulatory Mechanism 55%
  • Hormone Action 51%
  • Thermogenesis 45%
  • Heart Ventricle Hypertrophy 44%

• DFG Major Research Instrumentation: Intravital nanoscopy for investigating the blood-brain barrier

  Schwaninger, M. (Principal Investigator (PI))

  01.01.19 → …

  Project: DFG Projects › DFG Major Research Instrumentation

  • Tomography 100%
  • Electron Microscopy 100%
  • Blood Brain Barrier 100%
  • Microscopy 57%

• Sleep to be social: Sleep-dependent processing of social information about the self and others

  Diekelmann, S. (Principal Investigator (PI)) & Krach, S. (Principal Investigator (PI))

  01.01.19 → …

  Project: DFG Projects › DFG Individual Projects

  • Behavior (Neuroscience) 100%
  • Memory Consolidation 100%
  • Social Behavior 50%
  • Social Interaction 50%
  • Social Anxiety Disorder 50%

• Clinician Scientist School Luebeck: Connecting Brain, Metabolism, and Inflammation (BMI) – Mechanisms and Disease Expression

  Sadik, C. (Speaker, Coordinator), Busch, H. S. (Associated Staff), Erdmann, J. (Associated Staff), Grünewald, A. K. (Associated Staff), Ibrahim, S. (Associated Staff), Kaiser, F. (Associated Staff), Keck, T. (Associated Staff), Klein, C. (Associated Staff), Köhl, J. (Associated Staff), König, I. R. (Associated Staff), Lehnert, H. (Associated Staff), Lohmann, K. (Associated Staff), Münte, T. (Associated Staff), Nau, C. (Associated Staff), Oster, H. (Associated Staff), Riemekasten, G. (Associated Staff), Rupp, J. (Associated Staff), Schwaninger, M. (Associated Staff), Sina, C. (Associated Staff), Tronnier, V. M. (Associated Staff), Wollenberg, B. (Associated Staff) & Zillikens, D. (Associated Staff)

  01.01.18 → …

  Project: DFG Projects › DFG Clinician Scientist School Programme

  • Brain Metabolism 100%
  • Encephalitis 100%
  • Translational Research 50%
  • Autoimmune Disease 50%

• NEMO - an essential modulator of the blood-brain barrier

  Schwaninger, M. (Principal Investigator (PI)) & Wenzel, J. (Associated Staff)

  01.01.06 → …

  Project: DFG Projects › DFG Individual Projects

  • Blood Brain Barrier 100%
  • Blood-Brain Barrier 100%
  • Incontinentia pigmenti 80%
  • Endothelial Cell 60%
  • Necroptosis 40%
• Finished

  Intravital nanoscopy for investigating the blood-brain barrier

  Schwaninger, M. (Principal Investigator (PI)), Hüttmann, G. (Associated Staff) & König, P. (Associated Staff)

  01.01.19 → 31.12.23

  Project: DFG Projects › DFG Research Infrastructure: Scientific Instrumentation and Information Technology

  • Tomography 100%
  • Electron Microscopy 100%
  • Blood Brain Barrier 100%
  • Microscopy 57%

• Role of Tanycytes in the non-classical feedback regulation of the hypothalamic-pituitary-thyroid axis

  Müller-Fielitz, H. (Principal Investigator (PI))

  01.09.15 → 31.12.22

  Project: DFG Projects › DFG Individual Projects

  • Tanycyte 100%
  • Hypothalamic-Pituitary-Thyroid Axis 100%
  • Thyroid Hormone 100%
  • Protirelin Receptor 25%
  • Cre Recombinase 25%

• CRU 303: Pemphigoid Diseases - Molecular Pathways and their Therapeutic Potential

  Sadik, C. (Speaker, Coordinator), Zillikens, D. (Speaker, Coordinator), Ibrahim, S. (Principal Investigator (PI)), Baines, J. F. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Ehlers, M. (Principal Investigator (PI)), Hirose, M. (Principal Investigator (PI)), König, P. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Schwaninger, M. (Principal Investigator (PI)), Beek, N. (Principal Investigator (PI)), Erdmann, J. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Verschoor, A. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)) & Busch, H. S. (Principal Investigator (PI))

  01.04.15 → 31.12.23

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Bullous Pemphigoid 100%
  • Patient 60%
  • Bullous Disease 35%
  • Comorbidity 32%
  • Analysis 30%

• Novel brain endothelial-targeted gene therapy vectors to treat neuroinflammatory disease

  Schwaninger, M. (Speaker, Coordinator) & Trepel, M. (Speaker, Coordinator)

  01.08.14 → 31.07.17

  Project: DFG Projects › DFG Individual Projects

  • Brain 100%
  • Gene Therapy 92%
  • Incontinentia pigmenti 71%
  • Blood-Brain Barrier 68%
  • Microvessel 57%

• RTG 1957: Adipocyte-Brain Crosstalk

  Oster, H. (Speaker, Coordinator), Bader, M. (Project Staff), Kannenberg, S. (Project Staff), Brüggemann, N. (Project Staff), Heldmann, M. (Project Staff), Iwen, A. (Project Staff), Jöhren, O. (Project Staff), Kirchner, H. (Project Staff), Lehnert, H. (Project Staff), Mittag, J. (Project Staff), Münte, T. (Project Staff), Raasch, W. (Project Staff), Schmid, S. (Project Staff), Schulz, C. (Project Staff), Schwaninger, M. (Project Staff), Wenzel, J. (Project Staff) & Wilms, B. (Project Staff)

  01.05.14 → 30.04.23

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Thyroid Hormone Receptor 100%
  • Hormone Action 100%
  • Regulatory Mechanism 100%
  • Epigenetics 100%
  • Adipocyte 100%

• CRC/Transregio TRR 134, Project A06: Inflammatory signalling in the regulation of feeding

  Schwaninger, M. (Principal Investigator (PI)) & Wunderlich, F. T. (Principal Investigator (PI))

  01.01.14 → 01.01.18

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Interleukin 6 100%
  • Food Intake 66%
  • Interleukin-1 66%
  • Inflammatory Mediator 66%
  • In Vivo 33%

• CRC/Transregio TRR 134, Project A04: Role of orexin signalling in energy homeostasis and reward processing

  Jöhren, O. (Principal Investigator (PI)) & Hausen, A. C. (Principal Investigator (PI))

  01.01.14 → 01.01.18

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Orexin 100%
  • Receptor 40%

• SPP 1665, Subproject: Weak electric current stimulation and optogenetics to investigate sleep-dependent memory consolidation and ensemble reactivation

  Marshall, L. (Principal Investigator (PI)), Ponomarenko, A. (Principal Investigator (PI)) & Schweikard, A. (Principal Investigator (PI))

  01.08.13 → 31.12.21

  Project: DFG Projects › DFG Joint Research: Priority Programs

  • Optogenetics 100%
  • Memory Consolidation 100%
  • Behavior (Neuroscience) 40%

• CRC 654, Project A18: Sleep-dependent reorganization of neocortical microcircuit

  Born, J. (Principal Investigator (PI)) & Sato, T. (Principal Investigator (PI))

  01.01.13 → 31.12.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• CRC 654, Project A17: Remembering the past to anticipate the future: The functional role of sleep in predictive coding and prospective memory

  Diekelmann, S. (Principal Investigator (PI)) & Rauss, K. (Principal Investigator (PI))

  01.01.13 → 31.12.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• Mechanisms of glucose paradox in cerebral ischemia

  Schwaninger, M. (Speaker, Coordinator)

  01.06.11 → 31.05.15

  Project: DFG Projects › DFG Individual Projects

• CRC 654, Project A15: The function of sleep-related reactivations for long-term system consolidation

  Born, J. (Principal Investigator (PI)) & Rasch, B. (Principal Investigator (PI))

  01.01.09 → 31.12.12

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• Graduate School GSC 235: Graduate School for Computing in Medicine and Life Sciences

  Schweikard, A. (Speaker, Coordinator), Anders, S. (Project Staff), Barkhausen, J. (Project Staff), Buzug, T. (Project Staff), Erdmann, J. (Project Staff), Fischer, B. (Project Staff), Fischer, S. (Project Staff), Habermann, J. K. (Project Staff), Hartmann, E. (Project Staff), Hilgenfeld, R. (Project Staff), Hofmann, U. (Project Staff), Klein, C. (Project Staff), Kruse, C. (Project Staff), Marshall, L. (Project Staff), Martinetz, T. (Project Staff), Mertins, A. (Project Staff), Münte, T. (Project Staff), Oltmanns, K. (Project Staff), Schneider, S. (Project Staff), Schunkert, H. (Project Staff), Sczakiel, G. (Project Staff), Tronnier, V. M. (Project Staff), Vogel, A. (Project Staff), Westermann, J. (Project Staff) & Zillikens, D. (Project Staff)

  01.11.07 → 31.12.14

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Brain 100%
  • Electroencephalogram 32%
  • Electrical Brain Stimulation 32%
  • Ventral Striatum 28%
  • Nucleus Accumbens 27%

• CRC 654, Project A06: Brain stimulation and simulation to modulate sleep-dependent memory consolidation

  Marshall, L. (Principal Investigator (PI)), Martinetz, T. (Principal Investigator (PI)) & Mölle, M. (Principal Investigator (PI))

  01.07.05 → 30.06.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Slow-Wave Sleep 100%
  • Memory Consolidation 100%

• CRC 654, Subproject A04: Eye movements and the functional role of sleep. An investigation of dynamics, control mechanisms, cortical potentials and learning

  Gais, S. (Principal Investigator (PI)) & Kimmig, H. (Principal Investigator (PI))

  01.01.05 → 31.12.09

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• CRC 654: Plasticity and Sleep

  Born, J. (Speaker, Coordinator)

  01.01.05 → 31.12.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Germinal Center 100%
  • Follicular B Helper T Cells 55%
  • Laser Microdissection 50%
  • Sleep 50%
  • Autoantibody-Mediated Autoimmune Disease 25%

• CRC 654, Project Z: Research Center Coordination

  Born, J. (Principal Investigator (PI))

  01.01.05 → 31.12.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• CRC 654, Project B01: Sleep-associated learning processes of energy homeostasis

  Hallschmid, M. (Principal Investigator (PI)) & Schmid, S. (Principal Investigator (PI))

  01.01.05 → 31.12.17

  Project: DFG Projects › DFG Individual Projects

• CRC 654, Central Project Z02: Biosignal Analysis

  Born, J. (Principal Investigator (PI))

  01.01.05 → 31.12.09

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

• RU 126, Subproject: Cellular mechanisms in the pull principle

  Jöhren, O. (Principal Investigator (PI))

  01.01.05 → 31.12.11

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Hypoxia-Inducible Factors 100%
  • Procollagen-Proline Dioxygenase 88%
  • Gene Activation 88%
  • Procollagen Proline 2 Oxoglutarate 4 Dioxygenase 88%
  • Astrocyte 88%

• RU 457, Subproject: Neocortical processing modes as a reflection of memory processes during sleep

  Mölle, M. (Principal Investigator (PI)) & Melchert, U. (Associated Staff)

  01.01.02 → 31.12.07

  Project: DFG Projects › DFG Individual Projects

• RU 457, Project: Waking saccades and sleep REMs as indicators of visuomotor memory consolidation during sleep: influences of saccade type, memorization time and lesions of cortical saccade centers

  Heide, W. (Principal Investigator (PI)) & Gais, S. (Associated Staff)

  01.01.02 → 31.12.10

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

• Research Training Group RTG 791: Neural Developmental and Degenerative Processes: Basic Research and Clinical Implications

  Monyer, H. (Speaker, Coordinator), Bading, H. (Project Staff), Bartsch, D. (Project Staff), Ciccolini, F. (Project Staff), Draguhn, A. (Project Staff), Friedrich, R. (Project Staff), Hartmann, T. (Project Staff), Henn, F. A. (Project Staff), Hutter, H. (Project Staff), Misgeld, U. (Project Staff), Niehrs, C. (Project Staff), Offermanns, S. (Project Staff), Pollerberg, G. E. (Project Staff), Rappold, G. (Project Staff), Rozov, A. (Project Staff), Schwaninger, M. (Project Staff), Schütz, G. (Project Staff), Seeburg, P. H. (Project Staff), Unsicker, K. (Project Staff), Wisden, W. (Project Staff) & Witzemann, V. (Project Staff)

  01.01.02 → 31.12.08

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Alzheimer's Disease 100%
  • Synaptic Plasticity 100%

• Characterization of the role of NF-kB in cerebral ischemia and sepsis

  Schwaninger, M. (Principal Investigator (PI))

  01.01.00 → 31.12.03

  Project: DFG Projects › DFG Individual Projects

• Reperfusion in acute myocardial infarction: importance of adrenergic mechanisms

  Richardt, G. (Principal Investigator (PI)) & Dendorfer, A. (Associated Staff)

  01.01.99 → 31.12.05

  Project: DFG Projects › DFG Individual Projects