Clinic of Dermatology, Allergology and Venerology

Projects

Projects per year 1996 2013 2022 2023

• 11 Active
• 33 Finished

Projects per year

Search results

• Finished

  The role of complement in mucous membrane pemphigoid

  Ludwig, R. & Schmidt, E.

  01.01.19 → 31.12.22

  Project: DFG Projects › DFG Individual Projects

  • Bullous Pemphigoid 100%
  • Mucous Membrane 61%

• Pathogenicity of IgA-type autoantibodies in pemphigoid disease

  Ludwig, R., Nimmerjahn, F. & Recke, A.

  01.01.19 → 31.12.23

  Project: DFG Projects › DFG Individual Projects

  • Immunoglobulin A 100%
  • Autoantibodies 69%
  • Bullous Pemphigoid 57%
  • Fc(alpha) receptor 25%

• Bispecific antibodies for the treatment of the autoimmune disease epidermolysis bullosa acquisita

  Ludwig, R.

  01.01.17 → 31.12.22

  Project: DFG Projects › DFG Individual Projects

  • Chimeric Antigen Receptors 100%
  • Autoantibodies 95%
  • Epidermolysis Bullosa Acquisita 70%
  • T-Lymphocytes 64%
  • Autoimmune Diseases 64%

• Changing the anti-tumor immune response through differentially glycosylated tumor-specific IgG

  Prüßmann, J. & Mempel, T. R.

  01.01.16 → 31.12.19

  Project: DFG Projects › DFG Scholarships: Research Fellowships

  • Regulatory T-Lymphocytes 100%
  • Neoplasms 64%
  • Glycosylation 41%
  • Neoplasm Antigens 32%
  • Immunoglobulins 26%

• CRU 303: Pemphigoid Diseases - Molecular Pathways and their Therapeutic Potential

  Sadik, C., Zillikens, D., Ibrahim, S., Baines, J. F., Schmidt, E., Köhl, J., Ehlers, M., Hirose, M., König, P., Ludwig, R., Manz, R., Schwaninger, M., Beek, N., Erdmann, J., König, I. R., Verschoor, A., Karsten, C., Bieber, K. & Busch, H. S.

  01.04.15 → 31.12.23

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Bullous Pemphigoid 100%
  • Skin 50%
  • Autoimmune Diseases 40%
  • Inflammation 36%
  • Dermis 31%

• Interleukin 9 (IL-9) in der immunologischen Krebsabwehr beim malignen Melanom in Mäusen und Patienten

  Prüßmann, W.

  01.01.15 → 31.12.18

  Project: DFG Projects › DFG Scholarships: Research Fellowships

• Dual contribution of the spleen tyrosine kinase (SYK) to epidermolysis bullosa acquisita pathogenesis

  Ludwig, R., Samavedam, U. K., Recke, A., Kauderer, C. & Bieber, K.

  01.12.14 → 30.11.19

  Project: DFG Projects › DFG Individual Projects

  • Epidermolysis Bullosa Acquisita 100%
  • Syk Kinase 60%
  • Autoantibodies 35%

• Genetic basis of autoimmune pancreatitis

  Ibrahim, S., Jaster, R., Schneider, A. & Mayerle, J.

  01.06.14 → 31.05.19

  Project: DFG Projects › DFG Individual Projects

  • Autoimmune Pancreatitis 100%

• Keratinocytes as modulators of autoantibody-induced tissue injury

  Ludwig, R.

  01.08.13 → 31.07.16

  Project: DFG Projects › DFG Individual Projects

  • Epidermolysis Bullosa Acquisita 100%
  • Keratinocytes 61%
  • NF-kappa B 42%
  • anti-IgG 35%
  • Cytokines 34%

• Contribution of T cells to immune complex-induced tissue damage

  Ludwig, R. & Zillikens, D.

  01.08.13 → 31.07.16

  Project: DFG Projects › DFG Individual Projects

  • Vesiculobullous Skin Diseases 100%
  • T-Lymphocytes 40%
  • Epidermolysis Bullosa Acquisita 39%
  • Antigen-Antibody Complex 34%
  • Neutrophils 32%

• The role of leukotriene B4 and its receptor BLT1 in the pathogenesis of the prototypical organ-specific autoimmune disease epidermolysis bullosa acquisita

  Sadik, C., Zillikens, D. & Ludwig, R.

  01.07.13 → 30.06.17

  Project: DFG Projects › DFG Individual Projects

  • Leukotriene B4 100%
  • Epidermolysis Bullosa Acquisita 90%
  • Autoimmune Diseases 29%
  • Neutrophil Infiltration 26%

• Keratinocytes as modulators of autoantibody-induced tissue injury

  Ludwig, R.

  01.01.13 → 31.12.16

  Project: DFG Projects › DFG Individual Projects

  • Epidermolysis Bullosa Acquisita 100%
  • Keratinocytes 61%
  • NF-kappa B 42%
  • anti-IgG 35%
  • Cytokines 34%

• SPP 1395, Subproject: Mixed Models in Cell Communication and Cancer

  Busch, H. S., Börries, M. & Theis, F.

  01.01.12 → 31.12.18

  Project: DFG Projects › DFG Joint Research: Priority Programs

  • cell communication 100%
  • cytokines 48%
  • neoplasms 39%
  • independent component analysis 29%
  • skin (animal) 26%

• Longitudinal cloning and genetic characterization of human pemphigus autoantibodies in active disease, remission, and relapse

  Hammers, M. C. & Stanley, J. R.

  01.01.12 → 31.12.16

  Project: DFG Projects › DFG Scholarships: Research Fellowships

• RTG 1743: Genes, Environment and Inflammation

  Franke, A., Dempfle, A., Ibrahim, S., Laudes, M., Ludwig, R., Reiß, K., Rosenstiel, P. C. & Rupp, J.

  01.01.12 → 31.12.21

  Project: DFG Projects › DFG Joint Research: Research Training Groups

• Plasma cell depletion via activation of unfolded protein response: role of heat shock protein 90 inhibitors in a mouse model of autoantibody-mediated epidermolysis bullosa acquisita

  Kasperkiewicz, M.

  01.05.11 → 30.04.16

  Project: DFG Projects › DFG Individual Projects

• DFG RTG 1727: Modulation of Autoimmunity

  Zillikens, D., Ehlers, M., Hölscher, C., Kalies, K., Köhl, J., Lamprecht, P., Laskay, T., Ludwig, R., Manz, R., Müller, A., Petersen, F., Schmidt, E., Seeger, K., Westermann, J. & Yu, X.

  01.04.11 → 31.12.20

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Extracellular Traps 100%
  • Neutrophils 55%
  • Autoimmunity 43%

• Efficacy and safety of adjuvant immunoadsorption in pemphigus

  Eming, R. & Schmidt, E.

  01.01.10 → 01.01.18

  Project: DFG Projects › DFG Clinical Trials

  • Pemphigus 100%
  • Autoantibodies 40%
  • Mycophenolic Acid 30%
  • Blister 27%
  • Prednisolone 27%

• Studies on the importance of Fc receptors (FcR) in the pathogenesis of epidermolysis bullosa acquisita

  Ludwig, R.

  01.01.10 → 31.12.13

  Project: DFG Projects › DFG Individual Projects

• Leukotrien B4 als Regulator chemotaktisch-aktiver Substanzen in der Pathogenese chronischer Arthritiden

  Sadik, C.

  01.01.09 → 31.12.11

  Project: DFG Projects › DFG Scholarships: Research Fellowships

  • Neutrophil Infiltration 100%
  • Chemokines 82%
  • Arthritis 77%
  • Neutrophils 69%
  • Lipids 57%

• Leukotriene B4 as a regulator of chemotactic-active substances in the pathogenesis of chronic arthritis

  Sadik, C. & Luster, A. D.

  01.01.09 → 31.12.11

  Project: DFG Projects › DFG Individual Projects

  • Neutrophil Infiltration 100%
  • Chemokines 82%
  • Arthritis 77%
  • Neutrophils 69%
  • Lipids 57%

• Identification of susceptibility gene(s) controlling autoantibody production in collagen induced arthritis

  Ibrahim, S. & Yu, X.

  01.01.09 → 31.12.13

  Project: DFG Projects › DFG Individual Projects

  • Immune Tolerance 100%
  • Th17 Cells 98%
  • Arthritis 72%
  • loci 37%
  • arthritis 37%

• Graduate School GSC 235: Graduate School for Computing in Medicine and Life Sciences

  Schweikard, A., Anders, S., Barkhausen, J., Buzug, T., Erdmann, J., Fischer, B., Fischer, S., Habermann, J. K., Hartmann, E., Hilgenfeld, R., Hofmann, U., Klein, C., Kruse, C., Marshall, L., Martinetz, T., Mertins, A., Münte, T., Oltmanns, K., Schneider, S., Schunkert, H., Sczakiel, G., Tronnier, V. M., Vogel, A., Westermann, J. & Zillikens, D.

  01.11.07 → 31.12.14

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Brain 100%
  • Reward 84%
  • Sleep 79%
  • Deep Brain Stimulation 67%
  • Memory 63%

• EXC 306: Inflammation at Interfaces

  Schreiber, S., Bosch, T. C. G., Ehlers, S., Erdmann, J., Ernst, R., Franke, A., Gross, W., Hilgenfeld, R., Kabelitz, D., Köhl, J., Manz, R., Nebel, A., Niemann, S., Rabe, K. F., Rimbach, G., Rose-John, S., Rosenstiel, P. C., Saftig, P., Schaible, U., Schröder, J., Schütze, S., Siebert, R., Tautz, D., Weidinger, S. & Zillikens, D.

  01.01.07 → 31.12.18

  Project: DFG Projects › DFG Cluster of Excellence

  • Inflammation 100%
  • compound FP 2 90%
  • Medicine 62%
  • Interdisciplinary Research 57%
  • Precision Medicine 45%

• Regulation of inflammation in blister formation induced by antibodies against the dermo-epidermal junction zone

  Zillikens, D. & Sitaru, C.

  01.01.06 → 31.12.10

  Project: DFG Projects › DFG Individual Projects

• Contribution of junctional adhesion molecule (JAM)-B to the distinct steps of lymphocyte extravasation

  Ludwig, R.

  01.01.06 → 31.12.09

  Project: DFG Projects › DFG Individual Projects

  • P-Selectin 100%
  • Contact Dermatitis 86%
  • glucan sulfate 78%
  • Leukocyte Rolling 62%
  • Dimethyl Fumarate 57%

• The role of Toll like receptor 4 in the pathogenesis of collagen-induced arthritis

  Ibrahim, S. & Pierer, M.

  01.01.05 → 31.12.09

  Project: DFG Projects › DFG Individual Projects

  • Quantitative Trait Loci 100%
  • Experimental Arthritis 95%
  • arthritis 32%
  • Mitochondrial DNA 27%
  • Arthritis 26%

• Significance of platelets for the pathogenesis of chronic inflammatory dermatoses

  Ludwig, R. & Schultz, J. E.

  01.01.03 → 31.12.06

  Project: DFG Projects › DFG Individual Projects

• Autoimmunity against type VII collagen: role of the complement system in the induction and effector phase of the autoimmune response

  Zillikens, D. & Sitaru, C.

  01.01.02 → 31.12.09

  Project: DFG Projects › DFG Individual Projects

• Influence of collagen modifying enzymes on cross-linking

  Brinckmann, J.

  01.01.01 → 31.12.09

  Project: DFG Projects › DFG Individual Projects

  • 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine 100%
  • Collagen 35%
  • Systemic Scleroderma 33%
  • Skin 29%
  • Fibroblasts 29%

• Pathogenesis of blister formation in bullous pemphigoid: studies on signal transduction through the 180kDa auto-antigen (BP180/type XVII collagen)

  Zillikens, D.

  01.01.00 → 31.12.03

  Project: DFG Projects › DFG Individual Projects

• The role of Fas (CD95) in the pathogenesis of collagen induced arthritis

  Ibrahim, S.

  01.01.00 → 31.12.04

  Project: DFG Projects › DFG Individual Projects

• CRC 367, Project: Cross-linking pattern in collagen of sclerosing skin diseases

  Brinckmann, J. & Tronnier, M.

  01.01.96 → 31.12.00

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • skin diseases 100%
  • crosslinking 76%
  • collagen 71%