Center for Infectious and Inflammatory Diseases (ZIEL)

2024

A proof-of-principle study for the point-of-care detection of ESBL (CTX-M) by NG-Test ® CTX-M MULTI lateral flow assay in urine samples using a simplified method for use in a resource-limited setting.

Nurjadi, D., Chalin, A., Hauswaldt, S., Olson, L., Larsson, M., Östholm, Å., Velavan, T. P., Boutin, S., Rupp, J., Nilsson, L. E. & Hanberger, H., 08.2024, In: JAC-antimicrobial resistance. 6, 4, p. dlae103 dlae103.

Research output: Journal Articles › Journal articles › Research › peer-review

Are low-income and middle-income countries being neglected in genomic surveillance of the emergence and spread of multidrug-resistant Enterobacterales?

Nurjadi, D., Boutin, S. & Velavan, T. P., 08.2024, In: The Lancet. Microbe. 5, 8, p. 100854 100854.

Research output: Journal Articles › Journal articles › Research › peer-review

Bullous pemphigoid induced by IgG targeting type XVII collagen non-NC16A/NC15A extracellular domains is driven by Fc gamma receptor- and complement-mediated effector mechanisms and is ameliorated by neonatal Fc receptor blockade

Pigors, M., Patzelt, S., Reichhelm, N., Dworschak, J., Khil'chenko, S., Emtenani, S., Bieber, K., Hofrichter, M., Kamaguchi, M., Goletz, S., Köhl, G., Köhl, J., Komorowski, L., Probst, C., Vanderheyden, K., Balbino, B., Ludwig, R. J., Verheesen, P. & Schmidt, E., 02.2024, In: Journal of Pathology. 262, 2, p. 161-174 14 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice

Hirose, M., Leliavski, A., de Assis, L. V. M., Matveeva, O., Skrum, L., Solbach, W., Oster, H. & Heyde, I., 13.01.2024, In: Cells. 13, 2, 151.

Research output: Journal Articles › Journal articles › Research › peer-review

Clinical relevance of Staphylococcus saccharolyticus detection in human samples: a retrospective cohort study

Michels, R., Papan, C., Boutin, S., Alhussein, F., Becker, S. L., Nurjadi, D. & Last, K., 2024, In: Infection.

Research output: Journal Articles › Journal articles › Research › peer-review

Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy

Sayk, F., Hauswaldt, S., Knobloch, J. K., Rupp, J. & Nitschke, M., 2024, In: Frontiers in Public Health. 12, p. 1364664 1364664.

Research output: Journal Articles › Journal articles › Research › peer-review

Does the Impact of COVID-19 on Patients With Systemic Sclerosis Change Over Time?

Deibel, E., Carreira, P. E., Vonk, M., del Papa, N., Bečvář, R., Guillén-Del-Castillo, A., Campochiaro, C., Poormoghim, H., Liem, S., Lazzaroni, M. G., Giollo, A., Mekinian, A., de Vries-Bouwstra, J., De Santis, M., Balbir-Gurman, A., Mihai, C., De Luca, G., Moiseev, S., Zanatta, E. & Foti, R. & 44 others, Rednic, S., Denton, C., Cutolo, M., Belloli, L., Airo, P., Garzanova, L., Moroncini, G., İnanç, M., Panopoulos, S., Tandaipan, J. L., Chatelus, E., Rosato, E., Kuwana, M., Yavuz, S., Alegre-Sancho, J. J., Smith, V., Szűcs, G., Henes, J., Rodríguez-Pintó, I., Atzeni, F., Spierings, J., Truchetet, M. E., Milchert, M., Brito de Araujo, D., Riemekasten, G., Bernardino, V., Martin, T., del Galdo, F., Vacca, A., Mendoza, F., Midtvedt, Ø., Murdaca, G., Santiago, T., Codullo, V., Cacciapaglia, F., Walker, U., Brunborg, C., Tirelli, F., Allanore, Y., Furst, D. E., Matucci, M., Gabrielli, A., Distler, O. & Hoffmann-Vold, A. M., 01.2024, In: Arthritis Care and Research. 76, 1, p. 88-97 10 p.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

Dysregulated complement activation during acute myocardial infarction leads to endothelial glycocalyx degradation and endothelial dysfunction via the C5a:C5a-Receptor1 axis

Vahldieck, C., Löning, S., Hamacher, C., Fels, B., Rudzewski, B., Nickel, L., Weil, J., Nording, H., Baron, L., Kleingarn, M., Karsten, C. M. & Kusche-Vihrog, K., 2024, In: Frontiers in Immunology. 15, p. 1426526 1426526.

Research output: Journal Articles › Journal articles › Research › peer-review

DYT-THAP1: exploring gene expression in fibroblasts for potential biomarker discovery

Diaw, S. H., Delcambre, S., Much, C., Ott, F., Kostic, V. S., Gajos, A., Münchau, A., Zittel, S., Busch, H., Grünewald, A., Klein, C. & Lohmann, K., 04.2024, In: Neurogenetics. 25, 2, p. 141-147 7 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Emergence of extensively drug-resistant Pseudomonas aeruginosa ST308 co-producing Klebsiella pneumoniae carbapenemase and New Delhi metallo-β-lactamase in Viet Nam

Nurjadi, D., Nhat My, T., Göpel, L., Boutin, S., Song, L. H. & Velavan, T. P., 2024, In: The Lancet. Microbe. p. 100958 100958.

Research output: Journal Articles › Journal articles › Research › peer-review

Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Künstner, A., Schwarting, J., Witte, H. M., Xing, P., Bernard, V., Stölting, S., Lohneis, P., Janke, F., Salehi, M., Chen, X., Kusch, K., Sültmann, H., Chteinberg, E., Fischer, A., Siebert, R., von Bubnoff, N., Merz, H., Busch, H., Feller, A. C. & Gebauer, N., 05.2024, In: Leukemia. 38, 5, p. 1086-1098 13 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Genomic epidemiology of Streptococcus pyogenes from pharyngeal and skin swabs in Gabon

Boutin, S., Arnold, B., Alabi, A. S., Bélard, S., Toepfner, N. & Nurjadi, D., 02.07.2024, In: Microbiology spectrum. 12, 7, p. e0426523

Research output: Journal Articles › Journal articles › Research › peer-review

Gram-negative bloodstream infections in six German university hospitals, 2016-2020: clinical and microbiological features

Mischnik, A. & DZIF R-NET Study Group, 25.11.2024, (E-pub ahead of print) In: Infection.

Research output: Journal Articles › Journal articles › Research › peer-review

Heterogeneity of colistin resistance mechanism in clonal populations of carbapenem-resistant Klebsiella pneumoniae in Vietnam.

Sy, B. T., Boutin, S., Kieu Linh, L. T., Weikert-Asbeck, S., Eger, E., Hauswaldt, S., Nhat My, T., The, N. T., Rupp, J., Song, L. H., Schaufler, K., Velavan, T. P. & Nurjadi, D., 10.2024, In: The Lancet regional health. Western Pacific. 51, p. 101204

Research output: Journal Articles › Journal articles › Research › peer-review

Impact of Systemic Sclerosis-Associated Interstitial Lung Disease With and Without Pulmonary Hypertension on Survival: A Large Cohort Study of the German Network for Systemic Sclerosis

Moinzadeh, P., Bonella, F., Oberste, M., Weliwitage, J., Blank, N., Riemekasten, G., Müller-Ladner, U., Henes, J., Siegert, E., Günther, C., Kötter, I., Pfeiffer, C., Schmalzing, M., Zeidler, G., Korsten, P., Susok, L., Juche, A., Worm, M., Jandova, I. & Ehrchen, J. & 8 others, Sunderkötter, C., Keyßer, G., Ramming, A., Schmeiser, T., Kreuter, A., Lorenz, H. M., Hunzelmann, N. & Kreuter, M., 01.2024, In: Chest. 165, 1, p. 132-145 14 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Influence of non-pharmaceutical interventions during the COVID-19 pandemic on respiratory viral infections - a prospective population-based cohort study

Käding, N., Waldeck, F., Meier, B., Boutin, S., Borsche, M., Balck, A., Föh, B., Kramer, J., Klein, C., Katalinic, A. & Rupp, J., 2024, In: Frontiers in Public Health. 12, p. 1415778 1415778.

Research output: Journal Articles › Journal articles › Research › peer-review

Inhibitory effect of sorangicin A against mutant DNA-dependent RNA polymerase in the obligate intracellular bacterium Chlamydia trachomatis

Li, Q., Jansen, H., Hansen, G., Nurjadi, D., Herrmann, J., Stadler, M., Brönstrup, M., Müller, R., He, C., Graspeuntner, S., Rupp, J. & Shima, K., 05.2024, In: International Journal of Antimicrobial Agents. 63, 5, p. 107132 107132.

Research output: Journal Articles › Journal articles › Research › peer-review

Intravenous Ig Ameliorates Disease in a Murine Model of Anti–Laminin 332 Mucous Membrane Pemphigoid

Murthy, S., Patzelt, S., Künstner, A., Busch, H., Schmidt, E. & Sadik, C. D., 2024, In: Journal of Investigative Dermatology.

Research output: Journal Articles › Journal articles › Research › peer-review

Large area robotically assisted optical coherence tomography (LARA-OCT)

Lotz, S., Göb, M., Böttger, S., Ha-Wissel, L., Hundt, J., Ernst, F. & Huber, R., 01.06.2024, In: Biomed. Opt. Express. 15, 6, p. 3993-4009 17 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Molecular surveillance of carbapenem-resistant Enterobacterales in two nearby tertiary hospitals to identify regional spread of high-risk clones in Germany, 2019-2020

Boutin, S., Welker, S., Gerigk, M., Miethke, T., Heeg, K. & Nurjadi, D., 07.2024, In: Journal of Hospital Infection. 149, p. 126-134 9 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Nasal lavage microbiome, but not nasal swab microbiome, correlates with sinonasal inflammation in children with cystic fibrosis

Chung, J., Boutin, S., Frey, D. L., Joachim, C., Mall, M. A. & Sommerburg, O., 03.2024, In: Journal of Cystic Fibrosis. 23, 2, p. 226-233 8 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Optical coherence tomography-based imaging biomarkers for disease activity monitoring in plaque psoriasis

Ha-Wissel, L., Graßhoff, H., Göb, M., Mustafa, B., Huber, R., Zirpel, H., Yasak, H., Thaçi, D. & Hundt, J. E., 21.05.2024, In: Journal of the European Academy of Dermatology and Venereology. n/a, n/a, 1 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Optimization of the Diagnosis of Central Nervous System Infections in Vietnamese Hospitals: Results From a Retrospective Multicenter Study

Dong, D. V., Boutin, S., Sang, V. V., Manh, N. D., Hoan, N. X., Quang, H. X., Lien, T. T., Trang, V. D., The, N. T., Linh, L. T. K., Schmauder, K., Ueltzhöffer, V., Hafza, N., Hauswaldt, S., Rupp, J., Kremsner, P. G., Song, L. H., Nurjadi, D., Peter, S. & Velavan, T. P., 09.2024, In: Open forum infectious diseases. 11, 9, p. ofae531

Research output: Journal Articles › Journal articles › Research › peer-review

Pulmonary Events in ICU patients with hyperoxia: is it possible to relate arterial partial pressure of oxygen to coded diseases? A retrospective analysis

Stroh, L., Nurjadi, D., Uhle, F., Bruckner, T., Kalenka, A., Weigand, M. A. & Fiedler-Kalenka, M. O., 22.05.2024, (E-pub ahead of print) In: Medicina intensiva.

Research output: Journal Articles › Journal articles › Research › peer-review

The EC-COMPASS: Long-term, multi-centre surveillance of Enterobacter cloacae complex - a clinical perspective

Mauritz, M. D., Claus, B., Forster, J., Petzold, M., Schneitler, S., Halfmann, A., Hauswaldt, S., Nurjadi, D. & Toepfner, N., 28.03.2024, (E-pub ahead of print) In: Journal of Hospital Infection. 148, p. 11-19 9 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Tracing clinically-relevant antimicrobial resistances in Acinetobacter baumannii-calcoaceticus complex across diverse environments: A study spanning clinical, livestock, and wastewater treatment settings

Savin, M., Sib, E., Heinemann, C., Eichel, V. M., Nurjadi, D., Klose, M., Andre Hammerl, J., Binsker, U. & Mutters, N. T., 04.2024, In: Environment International. 186, p. 108603

Research output: Journal Articles › Journal articles › Research › peer-review

Zoonotic and other veterinary chlamydiae - an update, the role of the plasmid and plasmid-mediated transformation

Marti, H., Shima, K., Boutin, S., Rupp, J., Clarke, I., Laroucau, K. & Borel, N., 20.11.2024, (E-pub ahead of print) In: Pathogens and disease.

Research output: Journal Articles › Journal articles › Research › peer-review

2023

A comprehensive analysis of genetic risk for metabolic syndrome in the Egyptian population via allele frequency investigation and Missense3D predictions

Bassyouni, M., Mysara, M., Wohlers, I., Busch, H., Saber-Ayad, M. & El-Hadidi, M., 12.2023, In: Scientific Reports. 13, 1, 20517.

Research output: Journal Articles › Journal articles › Research › peer-review

Cross-sectional analysis reveals autoantibody signatures associated with COVID-19 severity

Baiocchi, G. C., Vojdani, A., Rosenberg, A. Z., Vojdani, E., Halpert, G., Ostrinski, Y., Zyskind, I., Filgueiras, I. S., Schimke, L. F., Marques, A. H. C., Giil, L. M., Lavi, Y. B., Silverberg, J. I., Zimmerman, J., Hill, D. A., Thornton, A., Kim, M., De Vito, R., Fonseca, D. L. M. & Plaça, D. R. & 11 others, Freire, P. P., Camara, N. O. S., Calich, V. L. G., Scheibenbogen, C., Heidecke, H., Lattin, M. T., Ochs, H. D., Riemekasten, G., Amital, H., Shoenfeld, Y. & Cabral-Marques, O., 02.2023, In: Journal of Medical Virology. 95, 2, p. e28538 e28538.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

Extending cBioPortal for Therapy Recommendation Documentation in Molecular Tumor Boards: Development and Usability Study

Renner, C., Reimer, N., Christoph, J., Busch, H., Metzger, P., Boerries, M., Ustjanzew, A., Boehm, D. & Unberath, P., 01.2023, In: JMIR Medical Informatics. 11, 1, e50017.

Research output: Journal Articles › Journal articles › Research › peer-review

Genetic Association and Differential RNA Expression of Histone (De)Acetylation-Related Genes in Pemphigus Foliaceus—A Possible Epigenetic Effect in the Autoimmune Response

Sulzbach Denardin, M., Bumiller-Bini Hoch, V., Salviano-Silva, A., Lobo-Alves, S. C., Adelman Cipolla, G., Malheiros, D., Augusto, D. G., Wittig, M., Franke, A., Pföhler, C., Worm, M., van Beek, N., Goebeler, M., Sárdy, M., Ibrahim, S., Busch, H., Schmidt, E., Hundt, J. E., Petzl-Erler, M. L. & Beate Winter Boldt, A., 29.12.2023, In: Life. 14, 1, 60.

Research output: Journal Articles › Journal articles › Research › peer-review

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Frank, D., Patnana, P. K., Vorwerk, J., Mao, L., Gopal, L. M., Jung, N., Hennig, T., Ruhnke, L., Frenz, J. M., Kuppusamy, M., Autry, R., Wei, L., Sun, K., Mohammed Ahmed, H. M., Künstner, A., Busch, H., Müller, H., Hutter, S., Hoermann, G. & Liu, L. & 39 others, Xie, X., Al-Matary, Y., Nimmagadda, S. C., Cano, F. C., Heuser, M., Thol, F., Göhring, G., Steinemann, D., Thomale, J., Leitner, T., Fischer, A., Rad, R., Röllig, C., Altmann, H., Kunadt, D., Berdel, W. E., Hüve, J., Neumann, F., Klingauf, J., Calderon, V., Opalka, B., Dührsen, U., Rosenbauer, F., Dugas, M., Varghese, J., Reinhardt, H. C., von Bubnoff, N., Möröy, T., Lenz, G., Batcha, A. M. N., Giorgi, M., Selvam, M., Wang, E., McWeeney, S. K., Tyner, J. W., Stölzel, F., Mann, M., Jayavelu, A. K. & Khandanpour, C., 21.12.2023, In: Blood. 142, 25, p. 2175-2191 17 p.

Research output: Journal Articles › Journal articles › Research › peer-review

MIRACUM-Pipe: An Adaptable Pipeline for Next-Generation Sequencing Analysis, Reporting, and Visualization for Clinical Decision Making

Metzger, P., Hess, M. E., Blaumeiser, A., Pauli, T., Schipperges, V., Mertes, R., Christoph, J., Unberath, P., Reimer, N., Scheible, R., Illert, A. L., Busch, H., Andrieux, G. & Boerries, M., 07.2023, In: Cancers. 15, 13, 3456.

Research output: Journal Articles › Journal articles › Research › peer-review

Persistence of foetal testicular features in patients with defective androgen signalling

Al-Sharkawi, M., Calonga-Solís, V., Dressler, F. F., Busch, H., Hiort, O. & Werner, R., 01.2023, In: European Journal of Endocrinology. 188, 1, vad007.

Research output: Journal Articles › Journal articles › Research › peer-review

The landscape of the immunoglobulin repertoire in endemic pemphigus foliaceus

Calonga-Solís, V., Olbrich, M., Ott, F., Adelman Cipolla, G., Malheiros, D., Künstner, A., Farias, T. D. J., Camargo, C. M., Petzl-Erler, M. L., Busch, H., Fähnrich, A. & Augusto, D. G., 2023, In: Frontiers in Immunology. 14, 1189251.

Research output: Journal Articles › Journal articles › Research › peer-review

2022

Emerging role of a systems biology approach to elucidate factors of reduced penetrance: transcriptional changes in THAP1-linked dystonia as an example

Diaw, S. H., Ott, F., Münchau, A., Lohmann, K. & Busch, H., 01.06.2022, In: Medizinische Genetik. 34, 2, p. 131-141 11 p.

Research output: Journal Articles › Journal articles › Research › peer-review

2021

A History of Asthma Increases the Risk of Bullous Pemphigoid: Insights from a Large Population-Based Study

Kridin, K., Ludwig, R. J., Tzur Bitan, D. & Cohen, A. D., 01.11.2021, In: Dermatology. 237, 6, p. 921-928 8 p.

Research output: Journal Articles › Journal articles › Research › peer-review

Diagnosis of epidermolysis bullosa acquisita: Multicentre comparison of different assays for serum anti-type VII collagen reactivity

Holtsche, M. M., Van Beek, N., Hashimoto, T., Di Zenzo, G., Zillikens, D., Prost-Squarcioni, C., Titeux, M., Hovnanian, A., Schmidt, E. & Goletz, S., 2021, In: Acta Dermato-Venereologica. 101, 3, p. adv00420 adv00420.

Research output: Journal Articles › Journal articles › Research › peer-review

Granzyme B inhibition reduces disease severity in autoimmune blistering diseases

Hiroyasu, S., Zeglinski, M. R., Zhao, H., Pawluk, M. A., Turner, C. T., Kasprick, A., Tateishi, C., Nishie, W., Burleigh, A., Lennox, P. A., Van Laeken, N., Carr, N. J., Petersen, F., Crawford, R. I., Shimizu, H., Tsuruta, D., Ludwig, R. J. & Granville, D. J., 01.12.2021, In: Nature Communications. 12, 1, p. 302 302.

Research output: Journal Articles › Journal articles › Research › peer-review

1 Citation (Scopus)

2018

Validity of eyeball estimation for range of motion during the cervical flexion rotation test compared to an ultrasound-based movement analysis system

Schäfer, A., Lüdtke, K., Breuel, F., Gerloff, N., Knust, M., Kollitsch, C., Laukart, A., Matej, L., Müller, A., Schöttker-Königer, T. & Hall, T., 03.08.2018, In: Physiotherapy Theory and Practice. 34, 8, p. 622-628 7 p.

Research output: Journal Articles › Journal articles › Research › peer-review

2016

Regulatory T cell frequencies are increased in preterm infants with clinical early-onset sepsis

Pagel, J., Hartz, A., Figge, J., Gille, C., Eschweiler, S., Petersen, K., Schreiter, L., Hammer, J., Karsten, C. M., Friedrich, D., Herting, E., Göpel, W., Rupp, J. & Härtel, C., 01.08.2016, In: Clinical and Experimental Immunology. 185, 2, p. 219-227 9 p.

Research output: Journal Articles › Journal articles › Research › peer-review

6 Citations (Scopus)

2015

Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse

Karsten, C. M., Laumonnier, Y., Eurich, B., Ender, F., Broker, K., Roy, S., Czabanska, A., Vollbrandt, T., Figge, J. & Köhl, J., 15.02.2015, In: Journal of Immunology. 194, 4, p. 1841-1855 15 p.

Research output: Journal Articles › Journal articles › Research › peer-review

20 Citations (Scopus)

2014

HIF-1α- and hypoxia-dependent immune responses in human CD4+CD25high T cells and T helper 17 cells.

Bollinger, T., Gies, S., Naujoks, J., Feldhoff, L., Bollinger, A., Solbach, W. & Rupp, J., 2014, In: Journal of Leukocyte Biology. 96, August, p. 1-8 8 p.

Research output: Journal Articles › Journal articles › Research › peer-review

2012

Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration

Singh, A., Nascimento, J. M., Kowar, S., Busch, H. & Boerries, M., 09.2012, In: Bioinformatics. 28, 18, p. i495-i501 bts410.

Research output: Journal Articles › Journal articles › Research › peer-review

2010

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

Riehl, A., Bauer, T., Brors, B., Busch, H., Mark, R., Németh, J., Gebhardt, C., Bierhaus, A., Nawroth, P., Eils, R., König, R., Angel, P. & Hess, J., 05.10.2010, In: BMC Genomics. 11, 1, 537.

Research output: Journal Articles › Journal articles › Research › peer-review

Center for Infectious and Inflammatory Diseases (ZIEL)

Research output

Search results