Center for Infectious and Inflammatory Diseases (ZIEL)

Projects

Projects per year 1991 2022 2026

• 31 Finished
• 33 Active

Projects per year

Search results

• Finished

  High throughput Imaging System for analysis of protein crystals

  Krey, T. (Principal Investigator (PI))

  01.01.20 → 31.12.20

  Project: DFG Projects › DFG Individual Projects

  • Crystal Growth 100%
  • Buffer Solution 100%
  • Photon Correlation Spectroscopy 100%
  • Protein Crystallization 100%
  • Light Scattering 100%

• Pathogenicity of IgA-type autoantibodies in pemphigoid disease

  Ludwig, R. (Principal Investigator (PI)), Nimmerjahn, F. (Principal Investigator (PI)) & Recke, A. (Principal Investigator (PI))

  01.01.19 → 31.12.23

  Project: DFG Projects › DFG Individual Projects

  • Pathogenicity 100%
  • Pemphigoid 100%
  • Immunoglobulin A 100%
  • Autoantibody 100%

• The role of complement in mucous membrane pemphigoid

  Ludwig, R. (Principal Investigator (PI)) & Schmidt, E. (Principal Investigator (PI))

  01.01.19 → 31.12.22

  Project: DFG Projects › DFG Individual Projects

  • Cicatricial Pemphigoid 100%
  • Complement Component 5a 26%

• Impact of metabolic changes triggered by microenvironmental factors on the efficacy of antimicrobials against Chlamydia trachomatis

  Kaufhold, I. (Principal Investigator (PI))

  01.01.16 → 31.12.19

  Project: DFG Projects › DFG Individual Projects

  • Chlamydia Trachomatis 100%
  • Host Cell 100%
  • Metabolism 50%
  • Energy Metabolism 50%
  • Gene Mutation 50%

• Changing the anti-tumor immune response through differentially glycosylated tumor-specific IgG

  Prüßmann, J. (Principal Investigator (PI)) & Mempel, T. R. (Associated Staff)

  01.01.16 → 31.12.19

  Project: DFG Projects › DFG Scholarships: Research Fellowships

  • Intravenous Immunoglobulin 87%
  • Tumor Antigen 75%
  • T Cell 50%
  • Antigen Presenting Cell 37%
  • Antigen-Presenting Cell 37%

• CRU 303: Pemphigoid Diseases - Molecular Pathways and their Therapeutic Potential

  Sadik, C. (Speaker, Coordinator), Zillikens, D. (Speaker, Coordinator), Ibrahim, S. (Principal Investigator (PI)), Baines, J. F. (Principal Investigator (PI)), Schmidt, E. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)), Ehlers, M. (Principal Investigator (PI)), Hirose, M. (Principal Investigator (PI)), König, P. (Principal Investigator (PI)), Ludwig, R. (Principal Investigator (PI)), Manz, R. (Principal Investigator (PI)), Schwaninger, M. (Principal Investigator (PI)), Beek, N. (Principal Investigator (PI)), Erdmann, J. (Principal Investigator (PI)), König, I. R. (Principal Investigator (PI)), Verschoor, A. (Principal Investigator (PI)), Karsten, C. (Principal Investigator (PI)), Bieber, K. (Principal Investigator (PI)) & Busch, H. S. (Principal Investigator (PI))

  01.04.15 → 31.12.23

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Bullous Pemphigoid 100%
  • Patient 60%
  • Bullous Disease 35%
  • Comorbidity 32%
  • Analysis 30%

• Interleukin 9 (IL-9) in der immunologischen Krebsabwehr beim malignen Melanom in Mäusen und Patienten

  Prüßmann, W. (Principal Investigator (PI))

  01.01.15 → 31.12.18

  Project: DFG Projects › DFG Scholarships: Research Fellowships

  • T Cell 100%
  • Melanoma 46%
  • Neoplasm 38%

• Keratinocytes as modulators of autoantibody-induced tissue injury

  Ludwig, R. (Speaker, Coordinator)

  01.08.13 → 31.07.16

  Project: DFG Projects › DFG Individual Projects

  • Autoantibody 100%
  • Keratinocyte 100%
  • Cytokine 62%
  • Neutrophil 50%
  • Cytokine Release 25%

• iRTG 1911: Immunregulation of Inflammation in Allergy and Infection

  Köhl, J. (Speaker, Coordinator), Härtel, C. (Project Staff), Hölscher, C. (Project Staff), Kalies, K. (Project Staff), Karsten, C. (Project Staff), König, P. (Project Staff), Laskay, T. (Project Staff), Laumonnier, Y. (Project Staff), Manz, R. (Project Staff), Petersen, F. (Project Staff), Rupp, J. (Project Staff), Schaible, U. (Project Staff), Sina, C. (Project Staff) & Verschoor, A. (Project Staff)

  01.04.13 → 31.12.22

  Project: DFG Projects › DFG Joint Research: Research Training Groups

  • Neutrophil 100%

• SPP 1395, Subproject: Mixed Models in Cell Communication and Cancer

  Busch, H. S. (Principal Investigator (PI)), Börries, M. (Principal Investigator (PI)) & Theis, F. (Principal Investigator (PI))

  01.01.12 → 31.12.18

  Project: DFG Projects › DFG Joint Research: Priority Programs

  • Cell Communication 100%
  • Cytokine 40%

• RTG 1743: Genes, Environment and Inflammation

  Franke, A. (Speaker, Coordinator), Dempfle, A. (Project Staff), Ibrahim, S. (Project Staff), Laudes, M. (Project Staff), Ludwig, R. (Project Staff), Reiß, K. (Project Staff), Rosenstiel, P. C. (Project Staff) & Rupp, J. (Project Staff)

  01.01.12 → 31.12.21

  Project: DFG Projects › DFG Joint Research: Research Training Groups

• CRU 274, Subproject: Role of platelets for tissue remodelling - modulation of angiogenesis, inflammation and apoptosis

  Langer, H. (Principal Investigator (PI)) & Verschoor, A. (Associated Staff)

  01.01.11 → 31.12.19

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

  • Angiogenesis 100%
  • Platelet 100%
  • Programmed Cell Death 100%
  • Receptor 100%
  • Inflammation 100%

• CRC 914, Project B04: Leukocyte migration and interaction in the context of the developing antibacterial T lymphocyte response

  Busch, D. (Principal Investigator (PI)) & Verschoor, A. (Principal Investigator (PI))

  01.01.11 → 31.12.23

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Leukocyte Migration 100%
  • T Cell 100%
  • Listeriosis 33%
  • Leukocyte Motility 33%
  • Leukocyte 33%

• Efficacy and safety of adjuvant immunoadsorption in pemphigus

  Schmidt, E. (Principal Investigator (PI)) & Eming, R. (Principal Investigator (PI))

  01.01.10 → 31.12.18

  Project: DFG Projects › DFG Clinical Trials

  • Pemphigus 100%
  • Autoantibody 100%
  • Immunoadsorption 100%
  • Remission 80%
  • Prednisolone 60%

• CRC 654, Project C08: Sleep-circadian oscillations in cytokine regulation

  Solbach, W. (Principal Investigator (PI)) & Oster, H. (Principal Investigator (PI))

  01.01.09 → 31.12.17

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • T-Helper Cell 100%
  • In Vivo 100%
  • Interleukin 2 49%
  • Leishmania 49%
  • CD40 Ligand 49%

• Leukotrien B4 als Regulator chemotaktisch-aktiver Substanzen in der Pathogenese chronischer Arthritiden

  Sadik, C. (Principal Investigator (PI))

  01.01.09 → 31.12.11

  Project: DFG Projects › DFG Scholarships: Research Fellowships

  • Neutrophil 100%
  • Inflammatory Arthritis 100%
  • Interleukin-1 33%
  • Arthritis 33%

• Leukotriene B4 as a regulator of chemotactic-active substances in the pathogenesis of chronic arthritis

  Sadik, C. (Principal Investigator (PI)) & Luster, A. D. (Associated Staff)

  01.01.09 → 31.12.11

  Project: DFG Projects › DFG Individual Projects

  • Neutrophil 100%
  • Inflammatory Arthritis 100%
  • Interleukin-1 33%
  • Arthritis 33%

• Identification of susceptibility gene(s) controlling autoantibody production in collagen induced arthritis

  Ibrahim, S. (Principal Investigator (PI)) & Yu, X. (Associated Staff)

  01.01.09 → 31.12.13

  Project: DFG Projects › DFG Individual Projects

  • Arthritis 100%
  • Th17 Cell 50%
  • Immune Tolerance 50%

• CRU 170: Central Trial Unit

  Moosig, F. (Principal Investigator (PI)) & Hellmich, B. (Principal Investigator (PI))

  01.01.07 → 31.12.11

  Project: DFG Projects › DFG Joint Research: Research Units/Clinical Research Units

• EXC 306: Inflammation at Interfaces

  Schreiber, S. (Speaker, Coordinator), Bosch, T. C. G. (Project Staff), Ehlers, S. (Project Staff), Erdmann, J. (Project Staff), Ernst, R. (Project Staff), Franke, A. (Project Staff), Gross, W. (Project Staff), Hilgenfeld, R. (Project Staff), Kabelitz, D. (Project Staff), Köhl, J. (Project Staff), Manz, R. (Project Staff), Nebel, A. (Project Staff), Niemann, S. (Project Staff), Rabe, K. F. (Project Staff), Rimbach, G. (Project Staff), Rose-John, S. (Project Staff), Rosenstiel, P. C. (Project Staff), Saftig, P. (Project Staff), Schaible, U. (Project Staff), Schröder, J.-M. (Project Staff), Schütze, S. (Project Staff), Siebert, R. (Project Staff), Tautz, D. (Project Staff), Weidinger, S. (Project Staff) & Zillikens, D. (Project Staff)

  01.01.07 → 31.12.18

  Project: DFG Projects › DFG Cluster of Excellence

  • Germinal Center 100%
  • Inflammation 75%
  • Follicular B Helper T Cells 55%
  • Laser Microdissection 50%
  • Genome Wide Association Study 50%

• SPP 1131, Subproject: AP-1 as the determinant of replicative and persistent intracellular C. pneumoniae infection

  Rupp, J. (Principal Investigator (PI)) & van Zandbergen, G. (Associated Staff)

  01.01.06 → 31.12.09

  Project: DFG Projects › DFG Joint Research: Priority Programs

  • Host Cell 100%
  • Programmed Cell Death 80%
  • Chlamydiae 40%
  • Cell Survival 40%

• Contribution of junctional adhesion molecule (JAM)-B to the distinct steps of lymphocyte extravasation

  Ludwig, R. (Principal Investigator (PI))

  01.01.06 → 31.12.09

  Project: DFG Projects › DFG Individual Projects

  • Cell Interaction 45%
  • L-Selectin 45%
  • Modulation 45%

• CRC 654, Project C03: Sleep and control of the antimicrobial immune response through CD4+CD25+ regulatory T cells

  Solbach, W. (Principal Investigator (PI))

  01.01.05 → 31.12.09

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Antimicrobial Immune Response 100%
  • Regulatory T Cell 100%
  • CD4 100%
  • CD25 100%
  • Sleep Pattern 33%

• Regulation of biofilm formation in S. epidermidis: interaction of known and evaluation of new regulators

  Knobloch, J. (Principal Investigator (PI)) & Mack, D. (Associated Staff)

  01.01.04 → 31.12.08

  Project: DFG Projects › DFG Individual Projects

• Significance of platelets for the pathogenesis of chronic inflammatory dermatoses

  Ludwig, R. (Principal Investigator (PI)) & Schultz, J. E. (Associated Staff)

  01.01.03 → 31.12.06

  Project: DFG Projects › DFG Individual Projects

• Charakterisierung der persistierenden Chlamydia pneumoniae Infektion

  Gieffers, J. (Principal Investigator (PI))

  01.01.03 → 31.12.08

  Project: DFG Projects › DFG Individual Projects

• SPP 1110, Subproject: The role of neutrophil granulocytes as target cells and transport vehicle for intracellular pathogens

  Solbach, W. (Associated Staff) & Laskay, T. (Principal Investigator (PI))

  01.01.02 → 31.07.07

  Project: DFG Projects › DFG Joint Research: Priority Programs

  • Infectious Agent 100%
  • Granulocyte 100%
  • Neutrophil Granulocyte 100%
  • Target Cell 100%
  • Leishmania 30%

• Pathogenesis of blister formation in bullous pemphigoid: studies on signal transduction through the 180kDa auto-antigen (BP180/type XVII collagen)

  Zillikens, D. (Principal Investigator (PI))

  01.01.00 → 31.12.03

  Project: DFG Projects › DFG Individual Projects

• The role of Fas (CD95) in the pathogenesis of collagen induced arthritis

  Ibrahim, S. (Principal Investigator (PI))

  01.01.00 → 31.12.04

  Project: DFG Projects › DFG Individual Projects

• SPP 1047, Subproject: Mechanisms of biofilm formation by Staphylococcus epidermidis

  Mack, D. (Principal Investigator (PI)), Knobloch, J. (Associated Staff) & Rohde, H. (Associated Staff)

  01.01.98 → 31.12.05

  Project: DFG Projects › DFG Joint Research: Priority Programs

• CRC 263, Project A1: Dynamics of local defense reaction and pathogen distribution in an early phase of infection with Leishmania major

  Solbach, W. (Principal Investigator (PI))

  01.01.91 → 31.12.02

  Project: DFG Projects › DFG Joint Research: Collaborative Research Center/ Transregios

  • Leishmania major 100%
  • Integrin 100%
  • Pathogen 100%
  • Infectious Agent 100%
  • Dynamics 100%