Water-in-oil Emulsion as a Simple Phantom for Validation of Double Diffusion Encoding MRI Sequences

Using Double Diffusion Encoding (DDE), it is possible to acquire microstructural information (like pore size and shape) that is not easily available non-invasively. Diverse phantoms were proposed to validate DDE pore size estimates. Yet, their development is complex and in the case of yeast suspensions, due to its low water content, sufficient SNR can only be achieved with many signal averages. Therefore, we suggest a water-in-oil emulsion for fast DDE sequence testing.