Abstract
We investigated changes of after-image duration in migraineurs and healthy controls (HCs) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. Forty-seven episodic (EMs) and 39 chronic migraineurs (CMs; interictal) were compared to 34 HCs for visual after-image duration. Additionally, seven EMs were investigated every consecutive day over 20 to 32 days using the identical paradigm throughout the migraine cycle. Interictally, the after-image duration was shorter compared to HCs, but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs, which oscillates over the migraine cycle. ANN NEUROL 2019;85:280–283.
| Originalsprache | Englisch |
|---|---|
| Zeitschrift | Annals of Neurology |
| Jahrgang | 85 |
| Ausgabenummer | 2 |
| Seiten (von - bis) | 280-283 |
| Seitenumfang | 4 |
| ISSN | 0364-5134 |
| DOIs | |
| Publikationsstatus | Veröffentlicht - 01.02.2019 |
Fördermittel
This work was supported by the German Research Foundation, SFB936/A5 to A.M. The funding sources did not influence study conduction in any way. We thank Ines Garcia-May for helping with data acquisition, Peter Kropp for providing the image and Jan Mehnert for methodological discussions.
UN SDGs
Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung
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SDG 3 – Gesundheit und Wohlergehen
Strategische Forschungsbereiche und Zentren
- Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)
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