Transient generalized chorea in influenza a encephalopathy

Jannik Prasuhn; Georg Royl; Klaus P. Wandinger; Norbert Brüggemann; Alexander Neumann; Thomas F. Münte

doi:10.7916/D8F495TP

Transient generalized chorea in influenza a encephalopathy

Jannik Prasuhn^*, Georg Royl, Klaus P. Wandinger, Norbert Brüggemann, Alexander Neumann, Thomas F. Münte

^*Korrespondierende/r Autor/-in für diese Arbeit

4 Zitate (Scopus)

Abstract

Background: Influenza A infections are a rare cause of movement disorders. Previously described patients have suffered from acute-onset myoclonus and/or dystonia or post-viral parkinsonism. Case Report: We present the case of a 74-year-old female patient with transient generalized chorea due to influenza A-mediated encephalopathy. Discussion: We discuss whether the clinical presentation and the magnetic resonance imaging changes may be attributable to cytokine-mediated encephalopathy or to direct cytotoxic effects of the virus. Additionally, we would like to make clinicians aware of this clinical sign in the context of viral encephalopathy.

Originalsprache	Englisch
Zeitschrift	Tremor and Other Hyperkinetic Movements
Jahrgang	8
DOIs	https://doi.org/10.7916/D8F495TP
Publikationsstatus	Veröffentlicht - 01.01.2018

Fördermittel

* To whom correspondence should be addressed. E-mail: [email protected] Editor: Elan D. Louis, Yale University, USA Received: July 19, 2018 Accepted: September 17, 2018 Published: October 9, 2018 Copyright: ’ 2018 Prasuhn et al. This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommercial–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original authors and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed. Funding: N.B. received funding from DFG (Deutsche Forschungsgemeinschaft), the Collaborative Center for X-linked Dystonia-Parkinsonism, and the Else-Kröner-Fresenius Foundation. T.F.M. received funding from DFG (Deutsche Forschungsgemeinschaft) and BMBF (Federal Ministry of Education and Research). Financial Disclosures: N.B. received honoraria from Grünenthal GmbH. J.P. received funding from the GSK foundation. We acknowledge financial support by Land Schleswig-Holstein within the funding program ‘Open Access Publikationsfonds’. Conflicts of Interest: The authors report no conflict of interest. Ethics Statement: This study was performed in accordance with the ethical standards detailed in the Declaration of Helsinki. The authors’ institutional ethics committee has approved this study and all patients have provided written informed consent.

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title = "Transient generalized chorea in influenza a encephalopathy",

abstract = "Background: Influenza A infections are a rare cause of movement disorders. Previously described patients have suffered from acute-onset myoclonus and/or dystonia or post-viral parkinsonism. Case Report: We present the case of a 74-year-old female patient with transient generalized chorea due to influenza A-mediated encephalopathy. Discussion: We discuss whether the clinical presentation and the magnetic resonance imaging changes may be attributable to cytokine-mediated encephalopathy or to direct cytotoxic effects of the virus. Additionally, we would like to make clinicians aware of this clinical sign in the context of viral encephalopathy.",

author = "Jannik Prasuhn and Georg Royl and Wandinger, \{Klaus P.\} and Norbert Br{\"u}ggemann and Alexander Neumann and M{\"u}nte, \{Thomas F.\}",

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AU - Prasuhn, Jannik

AU - Royl, Georg

AU - Wandinger, Klaus P.

AU - Brüggemann, Norbert

AU - Neumann, Alexander

AU - Münte, Thomas F.

PY - 2018/1/1

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N2 - Background: Influenza A infections are a rare cause of movement disorders. Previously described patients have suffered from acute-onset myoclonus and/or dystonia or post-viral parkinsonism. Case Report: We present the case of a 74-year-old female patient with transient generalized chorea due to influenza A-mediated encephalopathy. Discussion: We discuss whether the clinical presentation and the magnetic resonance imaging changes may be attributable to cytokine-mediated encephalopathy or to direct cytotoxic effects of the virus. Additionally, we would like to make clinicians aware of this clinical sign in the context of viral encephalopathy.

AB - Background: Influenza A infections are a rare cause of movement disorders. Previously described patients have suffered from acute-onset myoclonus and/or dystonia or post-viral parkinsonism. Case Report: We present the case of a 74-year-old female patient with transient generalized chorea due to influenza A-mediated encephalopathy. Discussion: We discuss whether the clinical presentation and the magnetic resonance imaging changes may be attributable to cytokine-mediated encephalopathy or to direct cytotoxic effects of the virus. Additionally, we would like to make clinicians aware of this clinical sign in the context of viral encephalopathy.

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VL - 8

JO - Tremor and Other Hyperkinetic Movements

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ER -

Transient generalized chorea in influenza a encephalopathy

Abstract

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