Abstract
The glycoprotein thrombopoietin (TPO) is the major stimulator of megakaryopoiesis and platelet production. Hepatocytes express TPO mRNA at a constant rate. The plasma TPO level is inversely correlated to the mass of megakaryocytes and platelets, which degrade the hormone following its binding to specific membrane receptors.
Originalsprache | Englisch |
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Zeitschrift | News in Physiological Sciences |
Jahrgang | 17 |
Ausgabenummer | 1 |
Seiten (von - bis) | 6-10 |
Seitenumfang | 5 |
ISSN | 0886-1714 |
DOIs | |
Publikationsstatus | Veröffentlicht - 02.2002 |
Strategische Forschungsbereiche und Zentren
- Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)