The role of long-lived plasma cells in autoimmunity review

Sergio Arce; Giuliana Cassese; Anja Hauser; Thomas Dörner; Marcus Odendahl; Rudi Manz; Andreas Radbruch; Falk Hiepe

doi:10.1078/0171-2985-00204

The role of long-lived plasma cells in autoimmunity review

Sergio Arce, Giuliana Cassese, Anja Hauser, Thomas Dörner, Marcus Odendahl, Rudi Manz, Andreas Radbruch, Falk Hiepe

Institut für Systemische Entzündungsforschung

Charite - Universitatsmedizin Berlin

20 Zitate (Scopus)

Abstract

Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.

Originalsprache	Englisch
Zeitschrift	Immunobiology
Jahrgang	206
Ausgabenummer	5
Seiten (von - bis)	558-562
Seitenumfang	5
ISSN	0171-2985
DOIs	https://doi.org/10.1078/0171-2985-00204
Publikationsstatus	Veröffentlicht - 12.2002

Fördermittel

This work was supported by a grant from the Deutsche Forschungsgemeinschaft (SFB 421 C4).

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

SDG 3 – Gesundheit und Wohlergehen

Dokumente

10.1078/0171-2985-00204

Weitere Links

Link to publication in Scopus

Zitieren

@article{a849f88422224a37bdc2a9cf24a46507,

title = "The role of long-lived plasma cells in autoimmunity review",

abstract = "Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.",

author = "Sergio Arce and Giuliana Cassese and Anja Hauser and Thomas D{\"o}rner and Marcus Odendahl and Rudi Manz and Andreas Radbruch and Falk Hiepe",

note = "Funding Information: This work was supported by a grant from the Deutsche Forschungsgemeinschaft (SFB 421 C4).",

year = "2002",

month = dec,

doi = "10.1078/0171-2985-00204",

language = "English",

volume = "206",

pages = "558--562",

journal = "Immunobiology",

issn = "0171-2985",

publisher = "Elsevier GmbH",

number = "5",

}

TY - JOUR

T1 - The role of long-lived plasma cells in autoimmunity review

AU - Arce, Sergio

AU - Cassese, Giuliana

AU - Hauser, Anja

AU - Dörner, Thomas

AU - Odendahl, Marcus

AU - Manz, Rudi

AU - Radbruch, Andreas

AU - Hiepe, Falk

N1 - Funding Information: This work was supported by a grant from the Deutsche Forschungsgemeinschaft (SFB 421 C4).

PY - 2002/12

Y1 - 2002/12

N2 - Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.

AB - Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.

UR - https://www.scopus.com/pages/publications/0036992597

U2 - 10.1078/0171-2985-00204

DO - 10.1078/0171-2985-00204

M3 - Scientific review articles

C2 - 12607731

AN - SCOPUS:0036992597

SN - 0171-2985

VL - 206

SP - 558

EP - 562

JO - Immunobiology

JF - Immunobiology

IS - 5

ER -

The role of long-lived plasma cells in autoimmunity review

Abstract

Fördermittel

UN SDGs

Dokumente

Weitere Links

Fingerprint

Zitieren