Abstract
In a primary study on proinflammatory genetic profiles in stroke, the authors found the E469K polymorphism of the intercellular adhesion molecule 1 (ICAM-1) highly represented in the subgroup with spontaneous cervical artery dissection (sCAD). They further investigated the same genetic variant in a second group of 65 patients with sCAD. An association between sCAD and EE genotype was confirmed (odds ratio 3.16; p < 0.01), indicating that a proinflammatory predisposition is a risk factor for sCAD.
Originalsprache | Englisch |
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Zeitschrift | Neurology |
Jahrgang | 66 |
Ausgabenummer | 8 |
Seiten (von - bis) | 1273-1275 |
Seitenumfang | 3 |
ISSN | 0028-3878 |
DOIs | |
Publikationsstatus | Veröffentlicht - 01.04.2006 |
Strategische Forschungsbereiche und Zentren
- Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)