Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Olaf Wolkenhauer*, Charles Auffray, Simone Baltrusch, Nils Blüthgen, Helen Byrne, Marta Cascante, Andrea Ciliberto, Trevor Dale, Dirk Drasdo, David Fell, James E. Ferrell, Daniel Gallahan, Robert Gatenby, Ulrich Günther, Brian D. Harms, Hanspeter Herzel, Christian Junghanss, Manfred Kunz, Ingeborg Van Leeuwen, Philippe LenormandFrancis Levi, Michael Linnebacher, John Lowengrub, Philip K. Maini, Arif Malik, Katja Rateitschak, Owen Sansom, Reinhold Schäfer, Karsten Schürrle, Christine Sers, Santiago Schnell, Darryl Shibata, John Tyson, Julio Vera, Michael White, Boris Zhivotovsky, Robert Jaster

*Korrespondierende/r Autor/-in für diese Arbeit
35 Zitate (Scopus)

Abstract

Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.

OriginalspracheEnglisch
ZeitschriftCancer Research
Jahrgang70
Ausgabenummer1
Seiten (von - bis)12-13
Seitenumfang2
ISSN0008-5472
DOIs
PublikationsstatusVeröffentlicht - 01.01.2010

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

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