Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent

Ksenia Pumpor; Elisabeth Windeisen; Klaus Burger

doi:10.1002/jhet.5570400306

Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent

Ksenia Pumpor, Elisabeth Windeisen, Klaus Burger^*

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Biochemie

Universität Leipzig

16 Zitate (Scopus)

Abstract

The synthesis of heterocyclic α-mercapto acids starting from (RS)-thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.

Originalsprache	Englisch
Zeitschrift	Journal of Heterocyclic Chemistry
Jahrgang	40
Ausgabenummer	3
Seiten (von - bis)	435-442
Seitenumfang	8
ISSN	0022-152X
DOIs	https://doi.org/10.1002/jhet.5570400306
Publikationsstatus	Veröffentlicht - 2003

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Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

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title = "Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent",

abstract = "The synthesis of heterocyclic α-mercapto acids starting from (RS)-thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.",

author = "Ksenia Pumpor and Elisabeth Windeisen and Klaus Burger",

year = "2003",

doi = "10.1002/jhet.5570400306",

language = "English",

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pages = "435--442",

journal = "Journal of Heterocyclic Chemistry",

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T1 - Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent

AU - Pumpor, Ksenia

AU - Windeisen, Elisabeth

AU - Burger, Klaus

PY - 2003

Y1 - 2003

N2 - The synthesis of heterocyclic α-mercapto acids starting from (RS)-thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.

AB - The synthesis of heterocyclic α-mercapto acids starting from (RS)-thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.

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U2 - 10.1002/jhet.5570400306

DO - 10.1002/jhet.5570400306

M3 - Journal articles

AN - SCOPUS:0037961038

SN - 0022-152X

VL - 40

SP - 435

EP - 442

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 3

ER -

Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent

Abstract

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