Switching between Up and Down States in a conductance-based cortex model

Arne Weigenand; Hong-Viet V. Ngo; David Higgins; Thomas Martinetz; Jens Christian Claussen

Switching between Up and Down States in a conductance-based cortex model

Arne Weigenand, Hong-Viet V. Ngo, David Higgins, Thomas Martinetz, Jens Christian Claussen

Abstract

In a recent experiment [1] investigated the onand off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrateand- fire model having intrinsic inhibitory currents but lacking inhibitory connections [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of Up–states as obeserved in [1].

Originalsprache	Englisch
Seiten	1-4
Seitenumfang	4
Publikationsstatus	Veröffentlicht - 07.2010
Veranstaltung	PROCEEDINGS OF BIOSIGNAL 2010 - Berlin, Deutschland Dauer: 14.07.2010 → 16.07.2010

Tagung, Konferenz, Kongress

Tagung, Konferenz, Kongress	PROCEEDINGS OF BIOSIGNAL 2010
Land/Gebiet	Deutschland
Ort	Berlin
Zeitraum	14.07.10 → 16.07.10

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title = "Switching between Up and Down States in a conductance-based cortex model",

abstract = "In a recent experiment [1] investigated the onand off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrateand- fire model having intrinsic inhibitory currents but lacking inhibitory connections [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of Up–states as obeserved in [1].",

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AU - Weigenand, Arne

AU - Ngo, Hong-Viet V.

AU - Higgins, David

AU - Martinetz, Thomas

AU - Claussen, Jens Christian

PY - 2010/7

Y1 - 2010/7

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AB - In a recent experiment [1] investigated the onand off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrateand- fire model having intrinsic inhibitory currents but lacking inhibitory connections [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of Up–states as obeserved in [1].

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M3 - Conference Papers

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T2 - PROCEEDINGS OF BIOSIGNAL 2010

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Switching between Up and Down States in a conductance-based cortex model

Abstract

Tagung, Konferenz, Kongress

UN SDGs

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