Supraziliarer Mikrostent bei Offenwinkelglaukom: Klinische Ergebnisse einer prospektiven Multicenterstudie

S. Grisanti*, E. Margolina, H. Hoeh, M. Rau, C. Erb, I. Kersten-Gomez, H. B. Dick

*Korrespondierende/r Autor/-in für diese Arbeit
12 Zitate (Scopus)


Purpose: The suprachoroidal CyPass micro-stent is designed to be implanted into the supraciliary space to facilitate aqueous outflow along the uveoscleral pathway in patients with open-angle glaucoma (OAG). This study assessed the safety of micro-stent implantation in patients undergoing cataract surgery. Methods: In this multicenter study the CyPass microstent was implanted in patients with OAG undergoing cataract surgery. The implantation was performed using a minimally invasive, conjunctiva-sparing, ab interno intervention. Primary endpoints were safety aspects of the implant, secondary endpoints were the reduction of intraocular pressure (IOP) and topical medication. Results: There were no severe adverse events during or after surgery in any of the patients. In patients with controlled glaucoma (IOP < 21 mmHg) the average IOP remained constant throughout the 24 month follow-up period but mean medication use decreased from 2.0 at baseline to 1.1 postoperative. In patients with IOP of ≥ 21 mmHg the pressure was reduced by 37 % postoperatively and mean medication decreased from 2.2 at baseline to 1.0. Conclusions: The safety profile of combined cataract surgery and CyPass microstent implantation is acceptable and patients also showed a decrease in IOP and medication use.

Titel in ÜbersetzungSupraciliary microstent for open-angle glaucoma: Clinical results of a prospective multicenter study
Seiten (von - bis)548-552
PublikationsstatusVeröffentlicht - 06.2014


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