Sub-threshold panic attacks and agoraphobic avoidance increase comorbidity of mental disorders: Results from an adult general population sample

Christiane A. Pané-Farré*, Kristin Fenske, Jan P. Stender, Christian Meyer, Ulrich John, Hans Jürgen Rumpf, Ulfert Hapke, Alfons O. Hamm

*Korrespondierende/r Autor/-in für diese Arbeit
9 Zitate (Scopus)

Abstract

Full-blown panic attacks are frequently associated with other mental disorders. Most comorbidity analyses did not discriminate between isolated panic attacks vs. panic attacks that occurred in the context of a panic disorder and rarely evaluated the impact of comorbid agoraphobia. Moreover, there are no larger scale epidemiological studies regarding the influence of sub-threshold panic attacks. 4075 German-speaking respondents aged 18-64 were interviewed using the fully structured Munich Composite International Diagnostic Interview. Limited symptom attacks, isolated panic attacks, and panic disorder were associated with other lifetime DSM-IV disorders with monotonically increasing odds and increasing tendency for multiple comorbidities across the three groups. The presence of agoraphobia was associated with more frequent comorbidity in all panic subgroups and also in persons who never experienced panic attacks. The present study suggests that populations with isolated or limited symptom should be carefully attended to in clinical practice, especially if agoraphobia is present.

OriginalspracheEnglisch
ZeitschriftJournal of Anxiety Disorders
Jahrgang27
Ausgabenummer5
Seiten (von - bis)485-493
Seitenumfang9
ISSN0887-6185
DOIs
PublikationsstatusVeröffentlicht - 06.2013

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

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