Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

Eduard Baquero; Juliette Fedry; Pierre Legrand; Thomas Krey; Felix A. Rey

doi:10.1016/j.str.2018.09.014

Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

Eduard Baquero, Juliette Fedry, Pierre Legrand, Thomas Krey, Felix A. Rey^*

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Biochemie

10 Zitate (Scopus)

Abstract

Baquero et al. report the structure of the HAP2 gamete fusion protein of the Chlamydomonas reinhardtii alga, describing key elements required to bridge two opposite-type gametes and drive their fusion. Mutagenesis of these elements confirmed their membrane-interaction function. Additional specific HAP2 protein-protein interaction sites are described as potential fusion controls.

Originalsprache	Englisch
Zeitschrift	Structure
Jahrgang	27
Ausgabenummer	1
Seiten (von - bis)	113-124.e4
ISSN	0969-2126
DOIs	https://doi.org/10.1016/j.str.2018.09.014
Publikationsstatus	Veröffentlicht - 02.01.2019

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10.1016/j.str.2018.09.014

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abstract = "Baquero et al. report the structure of the HAP2 gamete fusion protein of the Chlamydomonas reinhardtii alga, describing key elements required to bridge two opposite-type gametes and drive their fusion. Mutagenesis of these elements confirmed their membrane-interaction function. Additional specific HAP2 protein-protein interaction sites are described as potential fusion controls.",

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AB - Baquero et al. report the structure of the HAP2 gamete fusion protein of the Chlamydomonas reinhardtii alga, describing key elements required to bridge two opposite-type gametes and drive their fusion. Mutagenesis of these elements confirmed their membrane-interaction function. Additional specific HAP2 protein-protein interaction sites are described as potential fusion controls.

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Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

Abstract

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