Site-directed mutagenesis of conserved charged residues in the helical region of the human C5a receptor: Arg206 determines high-affinity binding sites of C5a receptor

Medizin & Biologie

• Amino Acids 7%
• Anaphylatoxin C5a Receptor 80%
• Binding Sites 40%
• Competitive Binding 13%
• COS Cells 12%
• Epitopes 8%
• Fluorescent Antibody Technique 8%
• GTP-Binding Proteins 20%
• Guanosine Triphosphate 11%
• human C5AR1 protein 100%
• Ligands 29%
• Membranes 6%
• Mitochondrial Uncoupling Proteins 15%
• Oocytes 9%
• Phenotype 6%
• Population 4%
• seven-transmembrane G-protein-coupled receptor 16%
• Site-Directed Mutagenesis 56%
• Xenopus 11%