Serum levels of anti-type VII collagen antibodies detected by enzyme-linked immunosorbent assay in patients with epidermolysis bullosa acquisita are correlated with the severity of skin lesions

J. H. Kim, Y. H. Kim, S. C. Kim, E. B. Noh, S. E. Kim, A. Vorobyev, E. Schmidt, D. Zillikens, S. C. Kim

    Abstract

    Epidermolysis bullosa acquisita (EBA) is a chronic autoimmune subepidermal bullous disease characterized by circulating autoantibodies against type VII collagen. Detecting these autoantibodies is crucial for the diagnosis of this disease, and is also useful for measuring disease activity. Enzyme-linked immunosorbent assay (ELISA), a quantitative method to measure anti-type VII collagen antibody levels, is currently available to diagnose EBA.
    OriginalspracheEnglisch
    ZeitschriftJournal of the European Academy of Dermatology and Venereology
    Jahrgang27
    Ausgabenummer2
    ISSN0926-9959
    DOIs
    PublikationsstatusVeröffentlicht - 02.2013

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