Semichronic, collocated deep brain stimulation and multisite recording in rats

T. Gritsun; M. Litza; A. Hiller; A. Moser; Ulrich G. Hofmann

doi:10.1109/MMB.2006.251497

Semichronic, collocated deep brain stimulation and multisite recording in rats

T. Gritsun
, M. Litza
, A. Hiller
, A. Moser
, Ulrich G. Hofmann

Abstract

Multisite microelectrode recording represents a suitable procedure to study microphysiology and network interactions in the central nervous system on a short time scale. This enables a deeper understanding of recent neurochemical studies to investigate changes in the neurotransmitter GABA caused by deep brain stimulation at the same position. We describe in the following a semichronic procedure to implant a miniature system bringing both stimulation and monitoring probes in close proximity in the caudate putamen of freely behaving rats. New multisite microelectrodes to replace existing microdialysis probes are built from spun wires, characterized and described. The design of a closed loop recording and stimulating system is discussed.

Originalsprache	Englisch
Titel	2006 International Conference on Microtechnologies in Medicine and Biology
Seitenumfang	4
Herausgeber (Verlag)	IEEE
Erscheinungsdatum	01.12.2006
Seiten	85-88
Aufsatznummer	4281315
ISBN (Print)	978-142440338-7
DOIs	https://doi.org/10.1109/MMB.2006.251497
Publikationsstatus	Veröffentlicht - 01.12.2006
Veranstaltung	2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan Dauer: 09.05.2006 → 12.05.2006 Konferenznummer: 69840

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title = "Semichronic, collocated deep brain stimulation and multisite recording in rats",

abstract = "Multisite microelectrode recording represents a suitable procedure to study microphysiology and network interactions in the central nervous system on a short time scale. This enables a deeper understanding of recent neurochemical studies to investigate changes in the neurotransmitter GABA caused by deep brain stimulation at the same position. We describe in the following a semichronic procedure to implant a miniature system bringing both stimulation and monitoring probes in close proximity in the caudate putamen of freely behaving rats. New multisite microelectrodes to replace existing microdialysis probes are built from spun wires, characterized and described. The design of a closed loop recording and stimulating system is discussed.",

author = "T. Gritsun and M. Litza and A. Hiller and A. Moser and Hofmann, \{Ulrich G.\}",

year = "2006",

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language = "English",

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Gritsun, T, Litza, M, Hiller, A, Moser, A & Hofmann, UG 2006, Semichronic, collocated deep brain stimulation and multisite recording in rats. in 2006 International Conference on Microtechnologies in Medicine and Biology., 4281315, IEEE Proceedings, IEEE, S. 85-88, 2006 International Conference on Microtechnologies in Medicine and Biology , Okinawa, Japan, 09.05.06. https://doi.org/10.1109/MMB.2006.251497

TY - GEN

T1 - Semichronic, collocated deep brain stimulation and multisite recording in rats

AU - Gritsun, T.

AU - Litza, M.

AU - Hiller, A.

AU - Moser, A.

AU - Hofmann, Ulrich G.

N1 - Conference code: 69840

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Multisite microelectrode recording represents a suitable procedure to study microphysiology and network interactions in the central nervous system on a short time scale. This enables a deeper understanding of recent neurochemical studies to investigate changes in the neurotransmitter GABA caused by deep brain stimulation at the same position. We describe in the following a semichronic procedure to implant a miniature system bringing both stimulation and monitoring probes in close proximity in the caudate putamen of freely behaving rats. New multisite microelectrodes to replace existing microdialysis probes are built from spun wires, characterized and described. The design of a closed loop recording and stimulating system is discussed.

AB - Multisite microelectrode recording represents a suitable procedure to study microphysiology and network interactions in the central nervous system on a short time scale. This enables a deeper understanding of recent neurochemical studies to investigate changes in the neurotransmitter GABA caused by deep brain stimulation at the same position. We describe in the following a semichronic procedure to implant a miniature system bringing both stimulation and monitoring probes in close proximity in the caudate putamen of freely behaving rats. New multisite microelectrodes to replace existing microdialysis probes are built from spun wires, characterized and described. The design of a closed loop recording and stimulating system is discussed.

UR - https://www.scopus.com/pages/publications/35548939130

U2 - 10.1109/MMB.2006.251497

DO - 10.1109/MMB.2006.251497

M3 - Conference contribution

SN - 978-142440338-7

T3 - IEEE Proceedings

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EP - 88

BT - 2006 International Conference on Microtechnologies in Medicine and Biology

PB - IEEE

T2 - 2006 International Conference on Microtechnologies in Medicine and Biology

Y2 - 9 May 2006 through 12 May 2006

ER -

Semichronic, collocated deep brain stimulation and multisite recording in rats

Abstract

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