Semichronic, collocated deep brain stimulation and multisite recording in rats

T. Gritsun, M. Litza, A. Hiller, A. Moser, Ulrich G. Hofmann

Abstract

Multisite microelectrode recording represents a suitable procedure to study microphysiology and network interactions in the central nervous system on a short time scale. This enables a deeper understanding of recent neurochemical studies to investigate changes in the neurotransmitter GABA caused by deep brain stimulation at the same position. We describe in the following a semichronic procedure to implant a miniature system bringing both stimulation and monitoring probes in close proximity in the caudate putamen of freely behaving rats. New multisite microelectrodes to replace existing microdialysis probes are built from spun wires, characterized and described. The design of a closed loop recording and stimulating system is discussed.

OriginalspracheEnglisch
Titel2006 International Conference on Microtechnologies in Medicine and Biology
Seitenumfang4
Herausgeber (Verlag)IEEE
Erscheinungsdatum01.12.2006
Seiten85-88
Aufsatznummer4281315
ISBN (Print)978-142440338-7
DOIs
PublikationsstatusVeröffentlicht - 01.12.2006
Veranstaltung2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan
Dauer: 09.05.200612.05.2006
Konferenznummer: 69840

Fingerprint

Untersuchen Sie die Forschungsthemen von „Semichronic, collocated deep brain stimulation and multisite recording in rats“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren