Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine

Karsten Seeger; Sandro Lein; Gunter Reuter; Stefan Berger

doi:10.1021/bi047749x

Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine

Karsten Seeger, Sandro Lein, Gunter Reuter, Stefan Berger

Institut für Chemie und Metabolomics

Abstract

Saturation transfer difference NMR measurements were performed to investigate the interaction of S-adenosyl-l-methionine (AdoMet) with SU(VAR)3-9 from Drosophila melanogaster. SU(VAR)3-9 has a SET domain and plays an important role in methylation of lysine-9 of histone H3 which results in gene silencing. We determined the binding epitope of AdoMet and compared it with a crystal structure of another SET protein.

Originalsprache	Englisch
Titel	Biochemistry
Seitenumfang	6
Erscheinungsdatum	26.04.2005
Seiten	6208-6213
ISBN (Print)	0006-2960
DOIs	https://doi.org/10.1021/bi047749x
Publikationsstatus	Veröffentlicht - 26.04.2005

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Zugriff auf Dokument

10.1021/bi047749x

http://www.mendeley.com/research/saturation-transfer-difference-measurements-suvar39-sadenosyllmethionine

Zitieren

@inbook{9387d3b5aceb4e7cb2ceb3a9e84f33b7,

title = "Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine",

abstract = "Saturation transfer difference NMR measurements were performed to investigate the interaction of S-adenosyl-l-methionine (AdoMet) with SU(VAR)3-9 from Drosophila melanogaster. SU(VAR)3-9 has a SET domain and plays an important role in methylation of lysine-9 of histone H3 which results in gene silencing. We determined the binding epitope of AdoMet and compared it with a crystal structure of another SET protein.",

author = "Karsten Seeger and Sandro Lein and Gunter Reuter and Stefan Berger",

year = "2005",

month = apr,

day = "26",

doi = "10.1021/bi047749x",

language = "English",

isbn = "0006-2960",

series = "Biochemistry",

pages = "6208--6213",

booktitle = "Biochemistry",

}

TY - CHAP

T1 - Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine

AU - Seeger, Karsten

AU - Lein, Sandro

AU - Reuter, Gunter

AU - Berger, Stefan

PY - 2005/4/26

Y1 - 2005/4/26

N2 - Saturation transfer difference NMR measurements were performed to investigate the interaction of S-adenosyl-l-methionine (AdoMet) with SU(VAR)3-9 from Drosophila melanogaster. SU(VAR)3-9 has a SET domain and plays an important role in methylation of lysine-9 of histone H3 which results in gene silencing. We determined the binding epitope of AdoMet and compared it with a crystal structure of another SET protein.

AB - Saturation transfer difference NMR measurements were performed to investigate the interaction of S-adenosyl-l-methionine (AdoMet) with SU(VAR)3-9 from Drosophila melanogaster. SU(VAR)3-9 has a SET domain and plays an important role in methylation of lysine-9 of histone H3 which results in gene silencing. We determined the binding epitope of AdoMet and compared it with a crystal structure of another SET protein.

U2 - 10.1021/bi047749x

DO - 10.1021/bi047749x

M3 - Chapter

C2 - 15835908

SN - 0006-2960

T3 - Biochemistry

SP - 6208

EP - 6213

BT - Biochemistry

ER -

Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine

Abstract

UN SDGs

Zugriff auf Dokument

Fingerprint

Zitieren