TY - JOUR
T1 - Quantitative PCR analysis of different splice forms of NFAT5 revealed specific gene expression in fetal and adult brain
AU - Dalski, Andreas
AU - Wagner, Hans Joachim
AU - Schwinger, Eberhard
AU - Zühlke, Christine
N1 - Funding Information:
This work was supported by the Fritz Thyssen Stiftung [AZ1999 2060] (Köln). We would like to thank Nina Richter for excellent technical assistance.
PY - 2000/11/10
Y1 - 2000/11/10
N2 - To investigate sequences or mutations associated with neurodegenerative disorders, we performed analyses for the NFAT5 gene, which is located in the candidate region for the autosomal dominantly inherited spinocerebellar ataxia type 4 (SCA4). PCR based expression analyses detected NFAT5 transcripts with alternative splicing in 27 fetal and adult human tissues. Interestingly, by using quantitative methods on cDNA from fetal and adult human brain a significant difference at the expression level for one splice form could be shown. Copyright (C) 2000 Elsevier Science B.V.
AB - To investigate sequences or mutations associated with neurodegenerative disorders, we performed analyses for the NFAT5 gene, which is located in the candidate region for the autosomal dominantly inherited spinocerebellar ataxia type 4 (SCA4). PCR based expression analyses detected NFAT5 transcripts with alternative splicing in 27 fetal and adult human tissues. Interestingly, by using quantitative methods on cDNA from fetal and adult human brain a significant difference at the expression level for one splice form could be shown. Copyright (C) 2000 Elsevier Science B.V.
UR - http://www.scopus.com/inward/record.url?scp=0034634698&partnerID=8YFLogxK
U2 - 10.1016/S0169-328X(00)00202-3
DO - 10.1016/S0169-328X(00)00202-3
M3 - Journal articles
C2 - 11072102
AN - SCOPUS:0034634698
SN - 0169-328X
VL - 83
SP - 125
EP - 127
JO - Molecular Brain Research
JF - Molecular Brain Research
IS - 1-2
ER -