Protein translocation: Common themes from bacteria to man

Berit Jungnickel; Tom A. Rapoport; Enno Hartmann

doi:10.1016/0014-5793(94)00367-X

Protein translocation: Common themes from bacteria to man

Berit Jungnickel, Tom A. Rapoport^*, Enno Hartmann

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Biologie

Max Delbrück Center for Molecular Medicine

60 Zitate (Scopus)

Abstract

Protein transport across the endoplasmic reticulum membrane in eukaryotes and across the cytoplasmic membrane in bacteria have turned out to be highly related. The core component of the translocation apparatus is the Sec61/SecYp complex; at least two of its subunits are conserved in evolution. The Sec61/SecYp complex is involved in both co- and post-translational transport pathways. The two modes require probably distinct additional components.

Originalsprache	Englisch
Zeitschrift	FEBS Letters
Jahrgang	346
Ausgabenummer	1
Seitenumfang	5
ISSN	0014-5793
DOIs	https://doi.org/10.1016/0014-5793(94)00367-X
Publikationsstatus	Veröffentlicht - 06.06.1994

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abstract = "Protein transport across the endoplasmic reticulum membrane in eukaryotes and across the cytoplasmic membrane in bacteria have turned out to be highly related. The core component of the translocation apparatus is the Sec61/SecYp complex; at least two of its subunits are conserved in evolution. The Sec61/SecYp complex is involved in both co- and post-translational transport pathways. The two modes require probably distinct additional components.",

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AB - Protein transport across the endoplasmic reticulum membrane in eukaryotes and across the cytoplasmic membrane in bacteria have turned out to be highly related. The core component of the translocation apparatus is the Sec61/SecYp complex; at least two of its subunits are conserved in evolution. The Sec61/SecYp complex is involved in both co- and post-translational transport pathways. The two modes require probably distinct additional components.

UR - https://www.scopus.com/pages/publications/0028337335

U2 - 10.1016/0014-5793(94)00367-X

DO - 10.1016/0014-5793(94)00367-X

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Protein translocation: Common themes from bacteria to man

Abstract

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