Prognostic Value and Determinants of CMR-Derived Left Atrial Function Assessed in STEMI

Jakob Ledwoch, Thomas Stiermaier, Georg Fuernau, Suzanne de Waha, Charlotte Eitel, Janine Pöss, Steffen Desch, Gerhard Schuler, Holger Thiele, Ingo Eitel*

*Korrespondierende/r Autor/-in für diese Arbeit

Abstract

In recent years, assessment of left atrial (LA) volumes and function as prognostic markers after acute myocardial infarction (AMI) have gained increasing attention (1). Impairment of both systolic and diastolic left ventricular (LV) function is a frequent finding in patients after AMI and is mainly caused by the amount of infarcted tissue and scar formation (2). The diastolic dysfunction based increase in LA volumes and reduction of LA contractility have been found to be independent predictors for adverse clinical outcome after AMI (1). However, the direct influence of myocardial damage and reperfusion injury obtained by cardiac magnetic resonance (CMR) on LA function is unknown. The aim of the present study was therefore to evaluate the prognostic value of LA function in the setting of acute reperfused ST-segment elevation myocardial infarction (STEMI) and the relationship between LA performance and established CMR markers of myocardial damage. We hypothesized that impaired LA systolic function is associated with myocardial injury and an increased rate of future cardiovascular events.

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OriginalspracheEnglisch
ZeitschriftJACC: Cardiovascular Imaging
Jahrgang11
Ausgabenummer1
Seiten (von - bis)148-150
Seitenumfang3
ISSN1936-878X
DOIs
PublikationsstatusVeröffentlicht - 01.01.2018

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

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