Prevalence and Risk Factors of Emotional Distress in Patients With Prostate Cancer Assigned to External-beam Radiotherapy With or Without High-dose Rate Brachytherapy

Ahmed Al-Salool, Tamer Soror, Nathan Y. Yu, Dirk Rades*

*Korrespondierende/r Autor/-in für diese Arbeit

Abstract

Background/Aim: Upcoming radiotherapy for prostate cancer may lead to emotional distress. This study aimed to identify the prevalence and risk factors in a retrospective cohort of 102 patients. Patients and Methods: Thirteen characteristics were evaluated for six emotional problems. To account for multiple comparisons, Bonferroni correction was used; p-values <0.0038 were significant (alpha level <0.05). Results: Prevalence of worry, fears, sadness, depression, nervousness, and loss of interest in usual activities was 25%, 27%, 11%, 11%, 18%, and 5%, respectively. A greater number of physical problems was significantly associated with worry (p=0.0037) and fears (p<0.0001) and showed trends regarding sadness (p=0.011) and depression (p=0.011). Trends were also found for associations between younger age and worry (p=0.021), advanced primary tumor stage and fears (p=0.025), patient’s history of another malignancy and nervousness (p=0.035), and between external-beam radiotherapy alone and fears (p=0.042) or nervousness (p=0.037). Conclusion: Although the prevalence of emotional distress was comparably low, patients with risk factors may benefit from early psychological support.

OriginalspracheEnglisch
ZeitschriftAnticancer Research
Jahrgang43
Ausgabenummer5
Seiten (von - bis)2103-2109
Seitenumfang7
ISSN0250-7005
DOIs
PublikationsstatusVeröffentlicht - 05.2023

Strategische Forschungsbereiche und Zentren

  • Profilbereich: Lübeck Integrated Oncology Network (LION)
  • Zentren: Universitäres Cancer Center Schleswig-Holstein (UCCSH)

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