TY - JOUR
T1 - Prevalence and Risk Factors of Emotional Distress in Patients With Prostate Cancer Assigned to External-beam Radiotherapy With or Without High-dose Rate Brachytherapy
AU - Al-Salool, Ahmed
AU - Soror, Tamer
AU - Yu, Nathan Y.
AU - Rades, Dirk
N1 - Publisher Copyright:
© 2023 International Institute of Anticancer Research. All rights reserved.
PY - 2023/5
Y1 - 2023/5
N2 - Background/Aim: Upcoming radiotherapy for prostate cancer may lead to emotional distress. This study aimed to identify the prevalence and risk factors in a retrospective cohort of 102 patients. Patients and Methods: Thirteen characteristics were evaluated for six emotional problems. To account for multiple comparisons, Bonferroni correction was used; p-values <0.0038 were significant (alpha level <0.05). Results: Prevalence of worry, fears, sadness, depression, nervousness, and loss of interest in usual activities was 25%, 27%, 11%, 11%, 18%, and 5%, respectively. A greater number of physical problems was significantly associated with worry (p=0.0037) and fears (p<0.0001) and showed trends regarding sadness (p=0.011) and depression (p=0.011). Trends were also found for associations between younger age and worry (p=0.021), advanced primary tumor stage and fears (p=0.025), patient’s history of another malignancy and nervousness (p=0.035), and between external-beam radiotherapy alone and fears (p=0.042) or nervousness (p=0.037). Conclusion: Although the prevalence of emotional distress was comparably low, patients with risk factors may benefit from early psychological support.
AB - Background/Aim: Upcoming radiotherapy for prostate cancer may lead to emotional distress. This study aimed to identify the prevalence and risk factors in a retrospective cohort of 102 patients. Patients and Methods: Thirteen characteristics were evaluated for six emotional problems. To account for multiple comparisons, Bonferroni correction was used; p-values <0.0038 were significant (alpha level <0.05). Results: Prevalence of worry, fears, sadness, depression, nervousness, and loss of interest in usual activities was 25%, 27%, 11%, 11%, 18%, and 5%, respectively. A greater number of physical problems was significantly associated with worry (p=0.0037) and fears (p<0.0001) and showed trends regarding sadness (p=0.011) and depression (p=0.011). Trends were also found for associations between younger age and worry (p=0.021), advanced primary tumor stage and fears (p=0.025), patient’s history of another malignancy and nervousness (p=0.035), and between external-beam radiotherapy alone and fears (p=0.042) or nervousness (p=0.037). Conclusion: Although the prevalence of emotional distress was comparably low, patients with risk factors may benefit from early psychological support.
UR - http://www.scopus.com/inward/record.url?scp=85153900670&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/ed44926c-7d50-3cbb-a199-7e80cfb5bf84/
U2 - 10.21873/anticanres.16371
DO - 10.21873/anticanres.16371
M3 - Journal articles
C2 - 37097699
AN - SCOPUS:85153900670
SN - 0250-7005
VL - 43
SP - 2103
EP - 2109
JO - Anticancer Research
JF - Anticancer Research
IS - 5
ER -