Preparation and characterization of dextran-covered Fe34 nanoparticles for magnetic particle imaging

Kerstin Lüdtke-Buzug*, Sven Biederer, Timo Sattel, Tobias Knopp, Thorsten M. Buzug

*Korrespondierende/r Autor/-in für diese Arbeit

Abstract

Magnetic particle imaging (MPI) is a recently proposed method for the visualization of the spatial distribution of iron-oxide nanoparticles. The principle is based on the superparamagnetic nature of Fe3O 4 particles (SPIOs). Iron-oxide particles covered with dextran and derivates are widely used as contrast agents in MRI imaging. However, besides the spatial bio-distribution the image quality of the magnetic-particle imaging concept is determined by the particle diameter as well. Moreover, it is the particle size distribution that affects the measured magnetization response within MPI. Therefore, the spectral analysis of the synthesized nanoparticles is an essential assay step for particle validation.

OriginalspracheEnglisch
Titel4th European Conference of the International Federation for Medical and Biological Engineering
Redakteure/-innenJos Vander Sloten, Pascal Verdonck, Marc Nyssen, Jens Haueisen
Seitenumfang4
Band22
Herausgeber (Verlag)Springer Berlin Heidelberg
Erscheinungsdatum2008
Seiten2343-2346
ISBN (Print)978-3-540-89207-6
ISBN (elektronisch)978-3-540-89208-3
DOIs
PublikationsstatusVeröffentlicht - 2008
Veranstaltung4th European Conference of the International Federation for Medical and Biological Engineering - Antwerp, Belgien
Dauer: 23.11.200827.11.2008
Konferenznummer: 81647

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Biomedizintechnik

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