Practical fluorescence resonance energy transfer or molecular nanobioscopy of living cells

After formulating this philosophic question in a poetic form, Leonardo the Scientist, provides us with a real experimental (optical) setup. As I propose to treat the nature of the moon, it is necessary that I first describe the perspective of mirrors, whether plane, concave, or convex, (B.M.94r - Arundel MS in British Museum). Next, in the pages of Codex Atlanticus (C.A.190r), Leonardo invites us to Construct the glasses to see the moon magnified and half a millennium later we are still following him for, as Bulgakov famously said, Manuscripts do not burn!