Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

B. Kuraszkiewicz; H. Goszczyńska; T. Podsiadły-Marczykowska; M. Piotrkiewicz; P. Andersen; M. Gromicho; J. Grosskreutz; M. Kuźma-Kozakiewicz; S. Petri; B. Stubbendorf; K. Szacka; H. Uysal; M. de Carvalho

doi:10.3389/fnins.2020.00428

Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

B. Kuraszkiewicz, H. Goszczyńska, T. Podsiadły-Marczykowska, M. Piotrkiewicz^*, P. Andersen, M. Gromicho, J. Grosskreutz, M. Kuźma-Kozakiewicz, S. Petri, B. Stubbendorf, K. Szacka, H. Uysal, M. de Carvalho

^*Korrespondierende/r Autor/-in für diese Arbeit

5 Zitate (Scopus)

Abstract

It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.

Originalsprache	Englisch
Aufsatznummer	428
Zeitschrift	Frontiers in Neuroscience
Jahrgang	14
ISSN	1662-4548
DOIs	https://doi.org/10.3389/fnins.2020.00428
Publikationsstatus	Veröffentlicht - 26.05.2020
Extern publiziert	Ja

Strategische Forschungsbereiche und Zentren

Zentren: Neuromuskuläres Zentrum Schleswig-Holstein

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Dokumente

10.3389/fnins.2020.00428

Weitere Links

Link to publication in Scopus

Zitieren

Kuraszkiewicz, B., Goszczyńska, H., Podsiadły-Marczykowska, T., Piotrkiewicz, M., Andersen, P., Gromicho, M., Grosskreutz, J., Kuźma-Kozakiewicz, M., Petri, S., Stubbendorf, B., Szacka, K., Uysal, H., & de Carvalho, M. (2020). Potential Preventive Strategies for Amyotrophic Lateral Sclerosis. Frontiers in Neuroscience, 14, Artikel 428. https://doi.org/10.3389/fnins.2020.00428

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abstract = "It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.",

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AU - Andersen, P.

AU - Gromicho, M.

AU - Grosskreutz, J.

AU - Kuźma-Kozakiewicz, M.

AU - Petri, S.

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AU - de Carvalho, M.

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N2 - It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.

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